21 results match your criteria: "Goiter Lithium-Induced"
Thyroid Res
November 2021
Department of Otorhinolaryngology-Head and Neck Surgery, Nowon Eulji Medical Center, Eulji University School of Medicine, 68 Hangeulbiseok-Ro, Nowon-gu, Seoul, 01830, Republic of Korea.
Hosp Pract (1995)
August 2013
Division of Endocrinology, Diabetes, and Metabolism.
Goiters and hypothyroidism are well-known patient complications of the use of lithium for treatment of bipolar disease. However, the occurrence of lithium-induced hyperthyroidism is a more rare event. Many times, the condition can be confused with a flare of mania.
View Article and Find Full Text PDFThyroid Res
February 2013
Department of Medicine, Uganda Martyrs Hospital Lubaga, Kampala, Uganda.
Background: Lithium is an integral drug used in the management of acute mania, unipolar and bipolar depression and prophylaxis of bipolar disorders. Thyroid abnormalities associated with treatment with lithium have been widely reported in medical literature to date. These include goitre, hypothyroidism, hyperthyroidism and autoimmune thyroiditis.
View Article and Find Full Text PDFAnn Pharmacother
November 2002
Unité Fonctionnelle, Centre de pharmacovigilance, CHU de Grenoble, Grenoble, France.
J Affect Disord
June 2002
Medizinische Poliklinik, Klinikum Innenstadt der Ludwig-Maximilians-Universität München, Pettenkoferstr. 8a, 80336 München, Germany.
J Affect Disord
July 1998
Division of Psychological Medicine, Heath Park, Cardiff, UK.
Background: Little is known about the rate of thyroid disorders prior to lithium treatment, and which patients have a higher risk for developing such disorders during such treatment.
Method: Assessment of the thyroid histories and laboratory results of 209 lithium-treated patients with affective disorders from one catchment area.
Results: Six female patients had thyrotoxicosis before starting lithium, a rate of 4.
Acta Psychiatr Scand
July 1996
Department of Neurosciences B.B. Brodie, University of Cagliari, Italy.
A cohort of patients at various stages of lithium treatment was followed up for 6 years in order to evaluate the course of thyroid abnormalities. Ultrasonography confirmed that lithium can increase thyroid size, especially in cigarette smokers, and that it can affect the texture of the gland. However, the incidence of clinical hypothyroidism or specific thyroid autoimmunity does not exceed that found in the general population.
View Article and Find Full Text PDFA 26 year old woman with lithium induced thyrotoxicosis is reported. The thyrotoxicosis was associated with a non-tender diffuse goitre and a low radioiodine uptake by the gland. The thyrotoxicosis was reversible and remitted on withdrawal of the drug.
View Article and Find Full Text PDFFortschr Neurol Psychiatr
April 1995
Neurologische Klinik und Rehabilitationsklinik für Rückenmarkverletzte Hohe Warte, Bayreuth.
Controlled studies in 1990-1992 with Danish, Sardinian, and Hongkong-Chinese patients consistently revealed a prevalence of goiter of about 50% in lithium treated patients. This is far beyond the frequency generally assumed for Germany, the whole country still known to be an endemic goiter area. Hypothyroidism as a side effect of lithium occurs in a clearly different group of patients and is much less frequent, the overall incidence being not substantially different from the incidence in the general population.
View Article and Find Full Text PDFJ Endocrinol
November 1994
Department of Laboratory Medicine, Osaka University Medical School, Japan.
Endocrinology
August 1991
Endocrine Research Laboratory, West Los Angeles Veterans Administration Medical Center, California 90073.
Lithium has been reported to alter thyroid function and cause goiter in some patients. To explain the mechanism of lithium action in the thyroid gland, we studied the effect of lithium on thyroid function and cell growth in FRTL-5 rat thyroid cells and on de novo thyroid hormone formation in primary cultures of porcine thyroid follicles. TSH-induced iodide uptake was suppressed at 2 mM lithium in both FRTL-5 cells and porcine follicles.
View Article and Find Full Text PDFPsychiatry Res
October 1990
Istituto di Endocrinologia, University of Pisa, Italy.
J Clin Psychiatry
January 1988
Douglas Hospital Centre, Verdun, Quebec, Canada.
Seventy-six patients (6 males and 70 females) with diffuse toxic goiter, stages I-II, received lithium carbonate as a thyrostatic drug. The drug dose ranged from 900 to 1500 g depending on the degree of the disease clinical symptoms. The treatment with lithium lasted 45 days.
View Article and Find Full Text PDFActa Pharmacol Toxicol (Copenh)
July 1978
J Clin Endocrinol Metab
September 1976