2,176 results match your criteria: "Glaucoma Unilateral"
BMJ Case Rep
December 2024
Ophthalmology, Wellington Regional Hospital, Wellington South, New Zealand
Technologies that describe the biomechanics of the eye are of emerging importance in glaucoma and keratoconus. A defect in the wall of the eye would be expected to affect biomechanics, resulting in the dispersion of mechanical energy and more viscous rather than elastic behaviour. Here, a mildly myopic man in his 50s was noted to have a deep conduit beside the right optic disc which appeared to pass posteriorly to the optic nerve sheath or orbit.
View Article and Find Full Text PDFNeural Regen Res
November 2024
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, Guangdong Province, China.
Synaptic plasticity is essential for maintaining neuronal function in the central nervous system and serves as a critical indicator of the effects of neurodegenerative disease. Glaucoma directly impairs retinal ganglion cells and their axons, leading to axonal transport dysfuntion, subsequently causing secondary damage to anterior or posterior ends of the visual system. Accordingly, recent evidence indicates that glaucoma is a degenerative disease of the central nervous system that causes damage throughout the visual pathway.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
November 2024
Glaucoma Center of Excellence, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
J Fr Ophtalmol
November 2024
Department of Ophthalmology, Centre for Sight Africa, Nkpor, Anambra State, Nigeria; Department of Ophtalmology, Gomabai Netralaya and Research Centre, Neemuch, Madhya Pradesh, India. Electronic address:
Br J Ophthalmol
November 2024
Kim's Eye Hospital, Seoul, Korea (the Republic of)
Background/aims: To identify whether an intact retinal nerve fibre layer (RNFL) thickness profile could determine the location of the earliest RNFL defect in glaucoma.
Methods: Retrospective longitudinal cohort study of patients with initial unilateral glaucoma who eventually developed new glaucoma in the fellow eye. Guided progression analysis (GPA) of serial optical coherence tomography (OCT) examinations was used to identify the angular locations of the earliest RNFL defect, peak and temporal edge of the baseline RNFL profile and major vessels based on the peripapillary OCT scan circle.
BMJ Case Rep
November 2024
Ophthalmology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
We report a case of unilateral serous choroidal effusion in a patient without prior glaucoma surgeries that developed within 1 week of starting topical dorzolamide. A Caucasian female in her 60s with a history of severe primary open-angle glaucoma in the left eye without prior glaucoma surgeries developed irritation and subsequently blurry vision in her left eye within 1 week of starting topical dorzolamide 2% in the left eye only. Funduscopic exam and B-scan ultrasound demonstrated a serous choroidal effusion in the nasal and temporal periphery.
View Article and Find Full Text PDFJ Clin Med
November 2024
Department of Ophthalmology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
J Clin Med
October 2024
Department of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.
: This study aims to explore the potential relationship between unilateral or asymmetric glaucoma and ipsilateral hearing impairment. : In this retrospective study, visual and hearing functions were assessed in patients with unilateral or asymmetric glaucoma. Correlations between retinal nerve fiber layer (RNFL) thickness, visual field mean deviation (MD) values, and pure tone audiometry (PTA) measurements across various frequencies were analyzed to explore potential associations between visual and ipsilateral hearing functions.
View Article and Find Full Text PDFInt Ophthalmol
November 2024
Faculty, Cornea and Anterior Segment Services, Shantilal Shanghvi Cornea Institute, L V Prasad Eye Institute, Hyderabad, Telangana, 500034, India.
Purpose: To describe the demographics, clinical characteristics, and management of corneal hydrops in patients presenting to a multi-tier ophthalmology hospital network in India.
Design: Cross-sectional hospital-based study.
Methods: Of the total of 3,140,941 new patients presenting between October 2010 and March 2022, patients with a clinical diagnosis of corneal hydrops in at least one eye were included in the study.
Exp Eye Res
December 2024
Department of Pharmaceutical Sciences, North Texas Eye Research Institute, University of North Texas Health Science Center, 3500 Camp Bowie Blvd., Fort Worth, TX, 76107, USA. Electronic address:
Ophthalmic Genet
October 2024
Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Saudi J Ophthalmol
October 2023
King Abdulaziz University Hospital, King Saud University Medical City, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Purpose: This study aimed to evaluate the long-term outcomes of primary pediatric cataract surgery and to identify determinants of success and recommendations to improve the care of patients with pediatric cataracts.
Methods: A cohort, retrospective study of cases who were operated as primary pediatric cataract surgery at King Khaled Eye Specialist Hospital. Patients who are 4 years old or younger and underwent primary cataract surgery with at least 3-year follow-up were enrolled in this study.
Rom J Ophthalmol
October 2024
Department of Ophthalmology, JIPMER, Puducherry, India.
Clin Ophthalmol
October 2024
Department of Ophthalmology, Stein Eye Institute, University of California Los Angeles, Los Angeles, CA, USA.
Semin Pediatr Neurol
October 2024
The University of Texas at Austin, Dell Medical School, Department of Neurology, 1601 Trinity St., Bldg. B, Stop Z0700 Austin, TX 78712, USA; Dell Children's Medical Center, 4910 Mueller Blvd Suite 300 Austin, TX 78723, USA. Electronic address:
BMC Ophthalmol
September 2024
Department of Ophthalmology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
J AAPOS
October 2024
Division of Ophthalmology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois; Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Electronic address:
Ophthalmol Retina
September 2024
Retina Department, Anand Eye Institute, Habsiguda, Hyderabad, Telangana, India.
Int Ophthalmol
September 2024
Haydarpaşa Numune Education and Research Hospital, Sadik Eratik Eye Institute, Division of Glaucoma, University of Health Sciences, Istanbul, Turkey.
Importance: If preperimetric glaucoma reduces patient-reported vision-related quality of life (VRQoL), clinicians might consider earlier and more aggressive treatment of some patients with ocular hypertension and early glaucoma.
Objective: To determine the impact of preperimetric glaucoma and early glaucomatous visual field (VF) loss on participants' VRQoL compared with participants who did not develop glaucoma in the Ocular Hypertension Treatment Study (OHTS).
Design, Setting, And Participants: This cross-sectional study used data from participants enrolled in the OHTS from 1994 to 1996 who completed 20-year examination follow-up and VRQoL surveys from January 7, 2016, to November 19, 2019.
Cornea
August 2024
FI Proctor Foundation, University of California, San Francisco, San Francisco, CA.
Purpose: The Steroids and Cross-linking for Ulcer Treatment Trial is an NIH-funded international, randomized, double-masked, sham and placebo-controlled clinical trial to determine the benefit of adjunctive corneal cross-linking with riboflavin and/or topical difluprednate in addition to topical antibiotic drops for treatment of smear-positive bacterial ulcers. The purpose of this study was to explore the baseline characteristics for infection of patients enrolled, and the ocular comorbidities of patients screened for inclusion.
Methods: Of the 2005 patients with smear-positive bacterial ulcers screened, 280 patients were enrolled.
Med Hypothesis Discov Innov Ophthalmol
August 2024
Department of Ophthalmology, 251 Hellenic Airforce General Hospital, Athens, Greece.
Background: Pseudoexfoliation syndrome (PES) is an age-related systemic condition that predominantly affects ocular structures and is characterized by the deposition of material on the lens, ciliary body, zonules, corneal endothelium, iris, and pupillary margin. We compared the corneal endothelial morphology, anterior segment parameters, corneal densitometry, and corneal topographic characteristics between the clinically affected and apparently normal fellow eyes of patients with clinically unilateral PES.
Methods: This was a comparative, cross-sectional study of 34 patients with clinically unilateral PES.
Exp Eye Res
October 2024
Storm Eye Institute, Medical University of South Carolina, Department of Ophthalmology, 167 Ashley Ave, Charleston, SC, 29425, USA. Electronic address:
Ceramides with varying acyl-chain lengths can have unique biological actions and hence, cellular responses to ceramides may depend not on their overall concentration but on that of individual ceramide species. The purpose of this study was to determine individual ceramide species impacting retinal ganglion cell (RGC) loss under the ocular hypertensive condition. Induced pluripotent stem cell (iPSC)-derived RGCs and primary cultures of human astrocytes were used to determine the effect of individual ceramide species on both RGC viability and astrocyte secretion of inflammatory cytokines in vitro.
View Article and Find Full Text PDFVision Res
October 2024
Department of Ophthalmology and Visual Sciences, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA; Department of Neurobiology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA. Electronic address:
Am J Ophthalmol Case Rep
December 2024
Department of Ophthalmology & Visual Sciences, Washington University School of Medicine, St. Louis, MO, 63110, USA.