621 results match your criteria: "Glaucoma Secondary Congenital"

Introduction And Importance: Sturge Weber Syndrome (SWS) is a congenital neurocutaneous disorder that affects several organs. Abnormal ocular findings are typically on the same side as the SWS. These changes can affect various parts of the eye, including the eyelid, front chamber, cornea, choroid, and retina.

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Purpose: The potential risks and benefits of cataract surgery, in context of congenital aniridia (CA), are not widely understood, yet. Our purpose was to investigate the effect of lens properties on visual acuity (VA), aniridia-associated keratopathy (AAK) stage and presence of glaucoma at the Homburg Aniridia Center.

Methods: CA subjects, examined at the Department of Ophthalmology of Saarland University between June 2003 and January 2022, were included.

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Purpose: In PAX6 syndrome, it is still not clear, whether prenatally, parallel to the iris tissue developmental anomaly, there is neural ectodermal, neural crest, or mesodermal cell deposition at the corneal endothelium, affecting endothelial structure and function. In addition, because of the postnatal corneal inflammation and commonly appearing secondary glaucoma, progressive endothelial changes are expected. Our purpose was to study the corneal endothelium in subjects with PAX6 aniridia, using in vivo confocal laser scanning microscopy.

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Aim: The main indications for Ahmed glaucoma valve (AGV) include neovascular glaucoma, congenital glaucoma, primary open angle glaucoma and patients with failed previous trabeculectomy. This article aims to investigate the complications of AGV in Jordanian glaucoma patients and to justify the main risk factors.

Methods: Retrospectively, we report 87 eyes of 83 patients who underwent AGV implantation for different indications.

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Glaucoma drainage devices (GDD) are used for patients with secondary glaucoma, such as uveitic or neovascular glaucoma, which is uncontrolled under local therapy. They are also used in patients with conjunctival scarring, for example after a previous vitrectomy or after unsuccessful previous glaucoma surgery, such as trabeculectomy. They are also a treatment option for congenital glaucoma, aphakic glaucoma or for the treatment of iridocorneoendothelial syndromes.

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Treatment Patterns of Childhood Glaucoma in the United States: Analysis of IRIS Registry (Intelligent Research in Sight).

Am J Ophthalmol

November 2024

From the Department of Ophthalmology (A.F., D.M.V., K.A., I.Y.C., D.S.F., A.L., A.C.L., J.W.M., P.P., K.S., T.E., N.Z., J.W.M., A.L.), Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, USA. Electronic address:

Article Synopsis
  • The study aimed to analyze treatment patterns for childhood glaucoma in the U.S. by examining patient records from 2013 to 2020.
  • It included 3069 patients, revealing that only 16.1% underwent surgery while 93.6% were treated with medications, with specific procedures varying based on the type of glaucoma.
  • Key factors influencing the need for surgeries included having primary congenital glaucoma, higher intraocular pressure, and being younger than one year at diagnosis.
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Human brain development is a complex process that requires intricate coordination of multiple cellular and developmental events. Dysfunction of lipid metabolism can lead to neurodevelopmental disorders. Lowe syndrome (LS) is a recessive X-linked disorder associated with proximal tubular renal disease, congenital cataracts and glaucoma, and central nervous system developmental delays.

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Triple treatment therapy for congenital stromal iris cyst.

Indian J Ophthalmol

November 2024

Cornea and External Disease, Cataract and Refractive, Ocular Oncology and Low Vision Services, All India Institute of Medical Sciences, New Delhi, India.

Article Synopsis
  • Iris cysts can cause a range of serious eye issues, so their complete removal is crucial to prevent recurrence and improve patient outcomes.
  • A new three-step technique was developed for managing iris cysts, which includes aspiration, wall removal, and cauterization while minimizing tissue damage.
  • This minimally invasive approach led to fewer complications, no reported recurrences in six months, and overall better visual outcomes compared to more aggressive treatments.
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Genetic analysis using next-generation sequencing and multiplex ligation probe amplification in Chinese aniridia patients.

Orphanet J Rare Dis

October 2024

Department of Ophthalmology and Visual Science, Eye and ENT Hospital, Shanghai Medical College, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.

Article Synopsis
  • Congenital aniridia is a rare eye condition leading to iris absence, which often results in serious complications like blindness and glaucoma.
  • A study of 60 patients in China identified genetic mutations, mostly in the PAX6 gene, using advanced genetic analysis methods that revealed a 98.3% mutation detection rate.
  • The findings highlight the genetic diversity of aniridia within families and emphasize the importance of understanding these mutations for potential therapeutic approaches.
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Background: Early therapeutic penetrating keratoplasty (TKP) for Acanthamoeba keratitis (AK) is thought to have a worse visual prognosis than the delayed optical penetrating keratoplasty (OKP) after successful conservative treatment of AK. This has led to a tendency to prolong conservative therapy and delay penetrating keratoplasty in patients with AK. This retrospective series presents the results of patients with AK that underwent early penetrating keratoplasty after reducing the corneal amoeba load through intensive conservative therapy, so-called "" (LLKP).

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Purpose: To investigate long-term visual outcomes and factors associated with low vision in patients with childhood glaucoma.

Materials And Methods: A retrospective review was conducted on the medical records of pediatric glaucoma patients at the Ondokuz Mayıs University Ophthalmology Clinic from 2005 to 2023. The patients were categorized into three groups: primary congenital glaucoma (PCG), secondary childhood glaucoma, and glaucoma following cataract surgery (GFCS).

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Article Synopsis
  • This study compared the effectiveness of two surgical methods - Bent Ab-Interno Needle Goniectomy (BANG) and traditional goniotomy - in treating primary congenital glaucoma (PCG) in infants aged 1 month to 1 year.
  • Both surgeries were performed on the same day, with outcomes like intraocular pressure control and need for antiglaucoma medications measured over a year.
  • Results showed no significant difference in IOP control or medication requirements between the two methods, but both improved corneal clarity; however, BANG required slightly more medications.
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Article Synopsis
  • Treatment with glucocorticoids after cataract surgery in children is important to avoid inflammation but can increase the risk of secondary glaucoma.
  • This study compared outcomes of high-dose versus low-dose glucocorticoid treatment in Danish children after cataract surgery, analyzing data from over 267 cases.
  • Results indicated that low-dose treatment was linked to a lower risk of glaucoma for children with larger axial lengths (≥18 mm), while high-dose glucocorticoids may need to be restricted in these patients.
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Objective: To compare the incidence of secondary glaucoma after cataract surgery performed in infancy in children with congenital rubella syndrome (CRS) and children with nonrubella cataracts and to identify associated risk factors.

Design: Retrospective case control study.

Participants: Children with CRS who had undergone cataract surgery in infancy and age-matched infants who had undergone cataract surgery for infantile cataracts were included.

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Ventriculoperitoneal shunt patients and glaucoma: a cohort analysis of the NPH registry.

Fluids Barriers CNS

July 2024

Neurosurgery of NeuroCenter, Unit of Neurosurgery, Institute of Clinical Medicine, Kuopio University Hospital, University of Eastern Finland, Kuopio, Finland.

Background: Idiopathic Normal Pressure Hydrocephalus (iNPH) is a chronic condition affecting the elderly. It is characterized by a triad of symptoms and radiological findings. Glaucoma is the leading cause of irreversible blindness worldwide.

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Purpose: Our study aimed to evaluate the indications and outcomes of intraocular lens (IOL) explantation surgeries in a tertiary eyecare center in Hungary.

Materials And Methods: This retrospective study included all IOL explantation surgeries performed between 2006 and 2020 at the Department of Ophthalmology of Semmelweis University, Budapest, Hungary. There were no exclusion criteria for this study.

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