3,281 results match your criteria: "Glaucoma Malignant"
Ocul Oncol Pathol
December 2024
The Retinoblastoma Service, Birmingham Children's Hospital, Birmingham, UK.
Background: Retinoblastoma (Rb) is the most common intraocular malignancy of childhood. The prognosis in Rb directly relates to the spread of disease beyond the eye, particularly to the central nervous system. Therefore, until the recent past, surgically entering an eye with active or recently active Rb was absolutely contraindicated in most centres around the world due to the risk of iatrogenic extraocular spread.
View Article and Find Full Text PDFJ Korean Med Sci
November 2024
Department of Obstetrics and Gynecology, Korea University College of Medicine, Seoul, Korea.
Spec Care Dentist
December 2024
Department of Basic Dental and Medical Science, College of Dentistry, University of Hail, Hail, Saudi Arabia.
Int J Mol Sci
October 2024
The Vision Center, Children's Hospital Los Angeles, Los Angeles, CA 90027, USA.
Recent advancements in aqueous humor (AH) cell-free DNA (cfDNA) genomics have opened new avenues for ex vivo molecular profiling of retinoblastoma (RB), the most common pediatric intraocular malignancy, where biopsy is typically prohibited. While these insights offer a genetic blueprint of the tumor, they lack multi-omic molecular phenotyping, which is essential for understanding the functional state. Extracellular vesicles (EVs), naturally present in AH, are promising by offering time-resolved phenotypic information.
View Article and Find Full Text PDFIndian J Ophthalmol
November 2024
Cornea and External Disease, Cataract and Refractive, Ocular Oncology and Low Vision Services, All India Institute of Medical Sciences, New Delhi, India.
JAMA Ophthalmol
December 2024
Department of Ophthalmology, University of California, San Francisco.
Int J Radiat Oncol Biol Phys
October 2024
Department of Ophthalmology, Teikyo University School of Medicine, Tokyo, Japan; Nishikasai Inouye Eye Hospital, Tokyo, Japan.
Purpose: This study aimed to evaluate the long-term results of carbon ion radiation therapy (CIRT) for choroidal malignant melanoma (CMM), especially regarding the preservation of the eye and visual acuity (VA).
Methods And Materials: A total of 250 patients with intraocularly localized CMM treated with CIRT between January 2003 and September 2021 were included. The dose prescription included 60 to 85 Gy/4 to 5 fr, with only 68 Gy/4 fr used from 2018 onward.
Drugs Aging
November 2024
Division of Multiorgan Transplant and Hepatobiliary Surgery, Department of Surgery, The University of Texas Medical Branch, Galveston, TX, USA.
Semin Pediatr Neurol
October 2024
The University of Texas at Austin, Dell Medical School, Department of Neurology, 1601 Trinity St., Bldg. B, Stop Z0700 Austin, TX 78712, USA; Dell Children's Medical Center, 4910 Mueller Blvd Suite 300 Austin, TX 78723, USA. Electronic address:
BMC Vet Res
October 2024
Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
BMC Ophthalmol
October 2024
Aier Guangming Eye Hospital, Ningbo, 315000, Zhejiang, China.
Diagn Pathol
September 2024
Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan.
BMC Ophthalmol
September 2024
Recep Tayyip Erdogan University, Faculty of Medicine, Department of Ophthalmology, Rize, Turkey.
Purpose: The objective of this study was to evaluate anterior segment parameters across various phenotypes of polycystic ovary syndrome (PCOS), considering body mass index (BMI), serum estradiol and testosterone levels.
Materials And Methods: This prospective study included 116 women with PCOS, with each of the four distinct phenotype comprising 29 women. Additionally, 29 healthy women were included in the control group.
BMC Ophthalmol
September 2024
Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology & Visual Sciences Key Lab, Medical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information Technology, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, 1 Dong Jiao Min Lane,, Beijing, 100730, China.
J Craniofac Surg
September 2024
Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA.
Sarcomas are malignant tumors of connective tissue with a mesodermal origin that, in rare occasions, is presented in conjunctiva; undifferentiated pleomorphic sarcoma represents <1% of orbital tumors. It is characterized by not meeting the histologic, immunohistochemical, ultrastructural, or molecular criteria in the classification proposed by the World Health Organization. The authors present the case of an 82-year-old man, blind due to absolute glaucoma, who consulted for a conjunctival mass of a few months' evolution.
View Article and Find Full Text PDFBioorg Chem
December 2024
Natural and Medical Sciences Research Centre, University of Nizwa, P.O. Box 33, PC 616, Birkat Al Mauz, Nizwa, Sultanate of Oman. Electronic address:
Sci Rep
September 2024
Ophthalmology Department Affiliated Hospital of Guangdong Medical University, No. 57, South Renmin Avenue, Xiashan District, Zhanjiang, 524023, Guangdong Province, China.
Oncol Lett
November 2024
Eye Hospital, The First Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang 150001, P.R. China.
Ophthalmic Genet
December 2024
VST Center for Glaucoma Care, L V Prasad Eye Institute, Hyderabad, India.
Introduction: Mutations in gene have been linked to the development of refractory angle closure glaucoma (ACG). This study aims to delineate the clinical characteristics, genetic mutations, and disease progression in patients with autosomal recessive bestrophinopathy (ARB) and autosomal dominant Best vitelliform macular dystrophy (BVMD) who are presented with treatment-resistant ACG.
Methods: This retrospective analysis encompasses a comprehensive ophthalmic assessment, retinal imaging, and mutational profiling of six patients diagnosed with bestrophinopathy and concurrent ACG, with a particular emphasis on the risk of post-glaucoma filtration surgery malignant glaucoma (MG).
Ocul Oncol Pathol
September 2024
Sue Anschutz-Rodgers Eye Center, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Cureus
August 2024
Department of Ophthalmology, Universiti Kebangsaan Malaysia Medical Center, Kuala Lumpur, MYS.
Background: Eye removal surgeries, also called anophthalmic surgeries, are usually performed for a painful blinded eye due to various underlying causes. In this case review, we intended to study the indications, the types of anophthalmic surgeries, and post-operative complications related to eye removal surgeries.
Method: Five years of retrospective case review of surgical eye removals was conducted from 1st June 2018 to 31st May 2023 at Hospital Canselor Tuanku Muhriz (HCTM), University of Kebangsaan Malaysia (UKM).
BMJ Case Rep
August 2024
Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Delhi, Delhi, India
BMJ Open Ophthalmol
August 2024
Pharmacovigilance Department, Laboratorios Sophia SA de CV, Zapopan, Jalisco, Mexico.
BMC Geriatr
August 2024
Department of Cardiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, No. 1 DaHua Road, Dong Dan, Beijing, 100730, China.
Background: Chronic diseases, such as heart disease, cancer, and diabetes, are the leading causes of death and disability. Loneliness is linked to a greater risk of chronic disease. However, the lack of loneliness may change this relationship.
View Article and Find Full Text PDFOphthalmic Genet
December 2024
Department of Ophthalmology, University of Florida, Gainesville, Florida, USA.
Background: Prior research has shown a positive association of pseudoexfoliative glaucoma (PXG) in patients with non-melanoma skin cancer (NMSC), likely due to an increase in ultraviolet exposure associated with both. However, the role of NMSC as a genetic risk factor for PXG has not been examined. Thus, the goal of this study is to utilize Mendelian randomization with genome-wide association studies to evaluate for genetic causality while controlling for environmental confounders.
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