Tear Fluid Biomarkers and Quality of Life in People with Type 2 Diabetes and Dry Eye Disease.

Dry eye disease (DED) can be extremely distressing and is common in type 2 diabetes (T2D). To investigate potential biomarkers of DED in T2D, panels of proteins in tears, alongside clinical signs and symptoms of DED, were assessed. Patients were classified into four groups: T2D + DED ( = 47), T2D-only ( = 41), DED-only ( = 17) and healthy controls ( = 17).

The HEADS: UP Development Study: Working with Key Stakeholders to Adapt a Mindfulness-Based Stress Reduction Course for People with Anxiety and Depression after Stroke.

Background: Following stroke, rates of mood disorder are and remain high at five years (anxiety 34.4%; depression 23%). Structured mindfulness-based stress reduction (MBSR) courses are effective in a range of health conditions, but stroke survivors find adherence challenging.

Stroke Secondary Prevention: Everyone's Business.

Editorial [...

Family composition and age at menarche: Findings from the international Health Behaviour in School-aged Children study.

Background: Early menarche has been associated with father absence, stepfather presence and adverse health consequences in later life. This article assesses the association of different family compositions with the age at menarche. Pathways are explored which may explain any association between family characteristics and pubertal timing.

The influence of age, refractive error, visual demand and lighting conditions on accommodative ability in Malay children and adults.

Purpose: Near work, accommodative inaccuracy and ambient lighting conditions have all been implicated in the development of myopia. However, differences in accommodative responses with age and refractive error under different visual conditions remain unclear. This study explores differences in accommodative ability and refractive error with exposure to differing ambient illumination and visual demands in Malay schoolchildren and adults.

Patient-reported severity of dry eye and quality of life in diabetes.

Purpose: The purpose of the study was to assess the relationship between patient-reported severity of dry eye disease (DED), quality of life (QoL), presence of diabetic retinopathy (DR) and length of disease duration in people with type 1 diabetes mellitus (DM1) and type 2 diabetes mellitus (DM2).

Patients And Methods: A survey of 152 people (110 with and 42 without diabetes). All participants completed the Ocular Surface Disease Index (OSDI) and Dry Eye-related Quality of Life Score (DEQS) questionnaires.

The lived experiences of flemish midwifery students undertaking an internship in Suriname: A phenomenological study.

Objective: The aim of this study is to explore the lived experience of Flemish midwifery students undertaking an internship in Suriname.

Design: Hermeneutic phenomenological method as described by van Manen.

Methods: Seven midwifery students from one University College were selected purposefully for an in-depth interview during their internship abroad within the period October-November 2014.

Tear fluid biomarkers in ocular and systemic disease: potential use for predictive, preventive and personalised medicine.

In the field of predictive, preventive and personalised medicine, researchers are keen to identify novel and reliable ways to predict and diagnose disease, as well as to monitor patient response to therapeutic agents. In the last decade alone, the sensitivity of profiling technologies has undergone huge improvements in detection sensitivity, thus allowing quantification of minute samples, for example body fluids that were previously difficult to assay. As a consequence, there has been a huge increase in tear fluid investigation, predominantly in the field of ocular surface disease.

Repeatability of Pentacam peripheral corneal thickness measurements.

Purpose: To assess the repeatability of corneal thickness (CT) measurements, along the horizontal meridian up to 5mm from centre, in healthy eyes with the Pentacam instrument.

Methods: CT was measured in 82 right eyes (82 healthy subjects) at 11 corneal locations nominally 1mm apart along the horizontal meridian with Scheimpflug topography Pentacam. Two consecutive scans were performed in quick succession.