Preferential localization of a single spot in reaction-diffusion systems on non-spherical surfaces.

The present work systematically examines the effect of breaking the rotational symmetry of a surface on the spot positioning in reaction-diffusion (RD) systems. In particular, we study analytically and numerically the steady-state positioning of a single spot in RD systems on a prolate and an oblate ellipsoid. We adapt perturbative techniques to perform a linear stability analysis of the RD system on both ellipsoids.

Spatiotemporal Rainfall Variability and Trend Analysis of Shimsha River Basin, India.

Karnataka state has the second highest rainfed agricultural land in India, where agricultural output relies heavily on rainfall. The Shimsha basin, a sub-basin of Cauvery in the state, comes under a semi-arid region and predominantly consists of rainfed agricultural land. Rainfall patterns have changed dramatically with time resulting in frequent floods and droughts.

Theoretical Insights into the Optical and Excited State Properties of Donor-Phenyl Bridge-Acceptor Containing Through-Space Charge Transfer Molecules.

A comparative new strategy to enhance thermally activated delayed fluorescence (TADF) of through-space charge transfer (CT) molecules in organic light-emitting diodes (OLEDs) is investigated. Generally, TADF molecules adopt a twisted donor and acceptor structure to get a sufficiently small Δ and a higher value of the spin-orbit coupling matrix element (SOCME). However, molecules containing donor-phenyl bridge-acceptor (D-p-A) units and featuring π-stacked architectures have intramolecular CT contribution through space and exhibit high TADF efficiency.

Brain tissue segmentation in neurosurgery: a systematic analysis for quantitative tractography approaches.

Diffusion magnetic resonance imaging (dMRI) is a cutting-edge imaging method that provides a macro-scale in vivo map of the white matter pathways in the brain. The measurement of brain microstructure and the enhancement of tractography rely heavily on dMRI tissue segmentation. Anatomical MRI technique (e.

Development of Rice Straw-derived Biochar-Bentonite Composite and its Application for in situ Sequestration of Ammonium and Phosphate Ions in the Degraded Mine Soil.

Nutrient pollution has a diverse impact on the environment and human health. The presence of nutrients, such as ammonium and phosphate, is ubiquitous in the environment due to their extensive use in agricultural land and leaching through non-point sources. In this context, biochar-based composites could play an essential role in improving the soil's nutrient retention capacity.

An efficient registration-based approach for retinal blood vessel segmentation using generalized Pareto and fatigue pdf.

Segmentation of Retinal Blood Vessel (RBV) extraction in the retina images and Registration of segmented RBV structure is implemented to identify changes in vessel structure by ophthalmologists in diagnosis of various illnesses like Glaucoma, Diabetes, and Hypertension's. The Retinal Blood Vessel provides blood to the inner retinal neurons, RBV are located mainly in internal retina but it may partly in the ganglion cell layer, following network failure haven't been identified with past methods. Classifications of accurate RBV and Registration of segmented blood vessels are challenging tasks in the low intensity background of Retinal Image.

Synthesis and Biological Activity Evaluation of Pyrazole-1,2,4-triazole Hybrids: A Computer-aided Docking Studies.

Background: In the present study, a new series of 1,2,4-triazole linked to pyrazole derivatives (8a-j) of 4-(((7-amino-7H-[1,2,4]triazolo[4,3-b][1,2,4]triazol-6-yl)methyl)amino)-1,5-dimethyl- 2-phenyl-1H-pyrazol-3(2H)-one were synthesized and assessed for their antibacterial and anticancer activity.

Objective: Encouraged by these results, these analogues 4-(((7-amino-7H-[1,2,4]triazolo[4,3- b][1,2,4]triazol-6-yl)methyl)amino)-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-ones 8 have been synthesized and their inhibitory potential activity against different bacterial microorganisms and cancer cell lines was discussed.

Methods: All the synthesized final scaffolds were characterized by H NMR, C NMR, IR, mass and elemental analysis.

Socio-economic impact assessment of large-scale recycling of treated municipal wastewater for indirect groundwater recharge.

Reusing treated wastewater is an emerging solution to address freshwater scarcity, and surface water contamination faced worldwide. A unique large-scale wastewater recycling project was implemented to replenish groundwater by filling secondary treated wastewater (STW) into existing irrigation tanks in severely drought-hit areas of the Kolar districts of Southern India. This study quantifies the socio-economic impacts of this large-scale indirect groundwater recharge scheme.

Recent Progress in the Multicomponent Synthesis of Pyran Derivatives by Sustainable Catalysts under Green Conditions.

Pyrans are one of the most significant skeletons of oxygen-containing heterocyclic molecules, which exhibit a broad spectrum of medicinal applications and are constituents of diverse natural product analogues. Various biological applications of these pyran analogues contributed to the growth advances in these oxygen-containing molecules. Green one-pot methodologies for synthesising these heterocyclic molecules have received significant attention.

Identification and analysis of proline-rich proteins and hybrid proline-rich proteins super family genes from and their expression patterns to abiotic stress and zinc stimuli.

Systematic genome-wide analysis of revealed the identification of a total of 48 homologous genes comprising 21 proline-rich proteins () and 27 hybrid proline-rich proteins (). Comprehensive scrutiny of these gene homologs was conducted for gene structure, phylogenetic investigations, chromosome mapping, and subcellular localization of proteins. Promoter analysis uncovered the regions rich with phosphorous- (BIHD), ammonium-, sulfur-responsive (SURE), and iron starvation-responsive (IRO2) along with biotic, abiotic, and development-specific -elements.

Groundwater characterization and non-carcinogenic and carcinogenic health risk assessment of nitrate exposure in the Mahanadi River Basin of India.

Agriculture is the mainstay of India's economy and chemical fertilizers have been extensively used to meet increasing demands. Anthropogenic interventions at the soil surface, especially the application of nitrogenous fertilizers in agricultural fields, provide essential nutrients but become major pollutant sources in terrestrial ecosystems and aquatic environments. Groundwater samples from phreatic aquifers of the Mahanadi River Basin, Chhattisgarh, India, showed that the Ca-Mg-HCO freshwater type dominates, followed by the Ca-Mg-Cl- and Na-HCO types.

Synthesis of Hollow Gold Nanoparticles - Impact of Variables on Process Optimization.

Hollow gold nanoparticles (HAuNPs) are gold nanostructures with hollow interior. These particles have attracted a lot of interest due their excellent physicochemical and optical properties and their potential applications in diagnostics, sensing, imaging and assisting in tumor tracing and evaluating the effect of chemotherapy on tumor size, drug delivery and photothermal therapy. Sacrificial galvanic replacement using cobalt core is the most commonly used method for synthesis of HAuNPs.

Structural, electrical, and magnetic properties of nano SrLaFeO (X = 0.2-0.8).

The current work is mainly devoted to the synthesis, structural, electrical, and magnetic characterization of SrLaFeO (X = 0.2-0.8) (SLFO) nanoparticles synthesized via the hydrothermal technique.

Influence of fuel injection timing and trade-off study on the RCCI engine characteristics of Jatropha oil-diesel blend under 1-pentanol dual-fuel strategies.

The current study deals with a reactivity-controlled compression ignition (RCCI) engine working with 1-pentanol as the LRF and JOBD as the HRF. The composition of the pilot fuel includes 20% Jatropha oil and 80% diesel, which nearly matches the heating value and cetane index of petroleum diesel. The research focuses on studying the impact of the pilot fuel injection angle on the engine characteristics at full load conditions, and the pilot fuel injection angle varies from 19, 21, 23, 25, to 27° bTDC at a constant injection pressure of 600 bar.

Electric Monopole Transition from the Superdeformed Band in ^{40}Ca.

The electric monopole (E0) transition strength ρ^{2} for the transition connecting the third 0^{+} level, a "superdeformed" band head, to the "spherical" 0^{+} ground state in doubly magic ^{40}Ca is determined via e^{+}e^{-} pair-conversion spectroscopy. The measured value ρ^{2}(E0;0_{3}^{+}→0_{1}^{+})=2.3(5)×10^{-3} is the smallest ρ^{2}(E0;0^{+}→0^{+}) found in A<50 nuclei.

Process engineering strategy for large scale outdoor cultivation of Tetradesmus obliquus CT02 coupled with pH guided CO feeding.

A novel CO tolerant microalga Tetradesmus obliquus CT02, was previously evaluated to be a suitable bio refinery platform for synthesis of bioactive molecules, biodiesel, and biofertilizer. In the present study, a process engineering strategy was developed targeting improved growth performance of the strain at large scale under fluctuating outdoor environmental conditions. The strategy relies on maintaining pH of the culture at its optimal value via cascade control with CO feeding.

Intercalation of Nanoscale Multiferroic Spacers between the Two-Dimensional Interlayers of MXene.

We report a facile synthesis of MXene/bismuth ferrite (TiCT @ BiFeO) nanocomposites using hydrazine hydrate induced with the hydrothermal method. Preparation of the composite with hydrazine hydrate prevents the formation of BiFeO inside the matrix. The 25 wt % loading of BiFeO acts as spacers for the multilayer restacking of MXene flakes by retaining the (002) plane.

The pioneering role of metal-organic framework-5 in ever-growing contemporary applications - a review.

MOF-5 with a Zn(ii) cluster and terephthalic acid is a distinctive porous material among the metal-organic frameworks (MOFs), with unique physical, chemical and mechanical properties. MOF-5 based composites possess ample applications in modern chemistry. Huge surface area, suitable pore dimensions and scope of tunability make MOF-5 noteworthy in advanced materials.

Efficient Route to Canagliflozin via Anhydroketopyranose.

The development of an efficient route for the synthesis of Canagliflozin is reported. The anhydroketopyranose intermediate was isolated as a novel intermediate, which was used to prepare Canagliflozin API in high purity.

Anti-inflammatory Activity of PLA Inhibitory Saccharumoside-B.

Background: Saccharumoside-B and its analogs were found to have anticancer potential in vitro. The present study reports acute toxicity, molecular docking, ADMET profile analysis, and in vitro and in vivo anti-inflammatory activity of saccharumoside-B for the first time.

Methods: The in vitro enzyme inhibitory activity of saccharumoside-B on PLA2, COX-1, COX-2, and 5-LOX enzymes was evaluated by the cell-free method, and its effect on TNF-α, IL1β, and IL- 6 secretion levels in LPS stimulated THP-1 human monocytes was determined by ELISA-based methods.

Competitive metal-binding stoichiometry between calcium and strontium by cell wall proteins of Neurospora crassa.

Cell wall proteins from Neurospora crassa were isolated and evaluated to demonstrate their metal ability to bind Ca /Sr by loading the solubilized protein fraction on to immobilized metal affinity chromatography (IMAC) column pre-equilibrated with Ca /Sr . The sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis IMAC eluent, revealed ∼18 proteins with a similarity in the proteome pattern of Ca /Sr fractions. Diethyl aminoethyl chromatography showed five proteins in common in binding to Ca and Sr , were subjected to N-terminal sequencing.

Omicron, a new SARS-CoV-2 variant: assessing the impact on severity and vaccines efficacy.

The reply letter has been put forth in response to the comment made by Karthyayani Priya Satish entitled "India and the COVID-19 Vaccine." The comment was made in context to our published work "Exploring the covid-19 vaccine candidates against SARS-CoV-2 and its variants: where do we stand and where do we go?" The reply letter is concerned with the newer variant of SARS-CoV-2, i.e.

Investigating the role of fuel injection pressure and piston bowl geometries to enhance performance and emission characteristics of hydrogen-enriched diesel/1-pentanol fueled in CRDI diesel engine.

This paper deals with the effects of piston bowl geometry (hemispherical bowl, troded bowl, and re-entrant bowl) and fuel injection pressure (200 bar, 220 bar, and 240 bar) with hydrogen-diesel/1-pentanol (B20 (80% diesel and 20% pentanol) + 12 lpm of hydrogen) on the emission, combustion, and performance characteristics of a common rail direct injection diesel engine. Re-entrant bowl outperforms hemispherical and troded bowl in terms of brake thermal efficiency (5.67%) and hydrocarbon (8% reduction) with an increase in the fuel injection pressure (240 bar) at part and full load.

Arylidenemalononitriles as Versatile Synthons in Heterocyclic Synthesis.

Background: Arylidenemalononitriles are valuable synthons for the construction of a variety of novel complex heterocyclic motifs, fused heterocycle derivatives, and spirocyclic compounds. They are versatile chemical intermediates and have increasing applications in industry, agriculture, medicine, and biological science.

Objective: The aim of this review is to highlight the preparation methods and reactions of arylidenemalononitriles in the synthesis of various heterocyclic compounds.