190 results match your criteria: "Giant Condylomata Acuminata of Buschke and Lowenstein"
Surgical treatment of perineal giant condylomata acuminata (Buschke Lowenstein tumor): Case series from a developing country.
Int J Surg Case Rep
August 2024
Department of Surgery, University College Hospital Ibadan, Nigeria; Department of Surgery College of Medicine University of Ibadan, University College Hospital Ibadan, Nigeria.
Article Synopsis
- Giant condylomata acuminatum (GCA), also known as Buschke-Lowenstein tumor (BLT), is a rare, slow-growing tumor linked to low-risk HPV types 6 and 11, with low chances of becoming invasive cancer.
- The study involved three patients (one woman and two men) who underwent surgical excision for their BLT, with two also receiving surgical reconstruction and achieving positive outcomes.
- The authors emphasize the need for early symptom recognition, effective treatment options, awareness of recurrence risks, and preventive strategies against HPV.
[Pedunculated Giant Condyloma Acuminatum of the Scrotum].
Hinyokika Kiyo
May 2024
The Department of Urology, Kohka Public Hospital.
Article Synopsis
- A 71-year-old male presented with a mass in his scrotum that had been growing slowly and was not painful.
- A physical exam showed a soft, brown tumor measuring 4.5×3.5×3.0 cm, with lab tests indicating elevated blood sugar and a squamous carcinoma marker.
- The tumor was removed surgically, and no cancer was found; it was diagnosed as giant condyloma acuminatum, which often occurs in people with weakened immune systems.
Fine scalpel surgery: preserving the dartos muscle in a patient with scrotal and perigenital giant Buschke-Löwenstein tumors.
Wien Med Wochenschr
November 2024
Onkoderma-Clinic for Dermatology, Venereology and Dermatologic Surgery, General Skobelev 26, 1606, Sofia, Bulgaria.
Giant condyloma acuminatum (GCA), alternatively referred to as a Buschke-Löwenstein tumor (BLT), is an uncommon, benign, but locally aggressive form of verrucous carcinoma. The condition usually affects the male population under the age of 50 years; however, there have been rare reports of pediatric cases. Various risk factors such as smoking, diabetes, promiscuous behavior, poor hygiene, immunosuppression, and others are linked to the development of this condition.
View Article and Find Full Text PDFGiant inflamed fibroepithelial scrotal polyp mimicking an anogenital wart.
Int J STD AIDS
June 2024
North Manchester Sexual Health Clinic, The Northern Integrated Contraception, Sexual Health and HIV Service, Manchester Foundation Trust, Manchester, UK.
Article Synopsis
- * Examination revealed a large pink mass on the scrotum, resembling giant condyloma of Buschke and Lowenstein, along with smaller satellite lesions.
- * After unsuccessful treatments, a surgical excision was performed, and pathology revealed it to be an inflamed fibroepithelial polyp, marking it as the first reported case of this condition with warty features in an adult.
Successful application of aminolevulinic acid/photodynamic therapy in the treatment of giant condyloma acuminatum in an 87-year-old patient.
Photodiagnosis Photodyn Ther
February 2024
The First Affiliated Hospital of Zhengzhou University in China, No.1 East Road, Zhengzhou, Henan, China.
Article Synopsis
- Condyloma acuminatum is a common sexually transmitted infection caused by the human papillomavirus, leading to warts in the genital and perianal areas.
- Traditional treatments for this condition include methods like laser therapy and freezing, but they often come with downsides such as pain and high chances of recurrence.
- A recent case demonstrated successful treatment of an 87-year-old patient with ALA-PDT (Aminolevulinic acid/photodynamic therapy), achieving effective results without recurrence over six months, suggesting ALA-PDT should be more widely used.
Case report: Buschke-Lowenstein tumor, a giant anal condyloma acuminata.
Cir Cir
December 2023
Departamento de Cirugía General, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México.
Article Synopsis
- A 24-year-old man, who is HIV positive, presented with a large, painful anal condyloma that showed signs of infection.
- Pathology results indicated the presence of in situ squamous cell carcinoma within the condyloma.
- The findings revealed that the lesion was a Buschke-Lowenstein tumor, a type of giant condyloma associated with HPV.
A case of Kaposi sarcoma arising from giant condyloma acuminatum.
Asian J Surg
March 2024
Department of Colorectal Surgery, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China. Electronic address:
Giant condyloma acuminatum (Buschke-Lowenstein tumour) of the vagina during pregnancy.
BMJ Case Rep
October 2023
Department of Gynaecological Oncology, The Royal Hospital for Women, Randwick, New South Wales, Australia.
Article Synopsis
- A pregnant woman in her 30s discovered a large vaginal mass at 31 weeks, raising concerns about cancer.
- MRI and histopathology identified the mass as a giant condyloma acuminatum, a rare anogenital disease.
- The mass was surgically removed at 34 weeks, allowing the woman to have a successful vaginal birth.
"Free-Floating Anus": A Flap-Free Approach for Definitive Excision of Circumferential Giant Condyloma Acuminata.
Am Surg
December 2023
Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Giant condyloma acuminata (GCA), or Buschke-Löwenstein tumor, is a rare exophytic cauliflower-like growth in the anogenital region. The spectrum of treatment options is wide, ranging from the application of topical ointments to the performance of an abdominoperineal resection. Currently, wide local excision is the most common approach and may entail the creation of a protective loop ileostomy or implementation of flaps or grafts that facilitate closure.
View Article and Find Full Text PDFSquamous Cell Carcinoma of perineal area developed from the Buschke-Löwenstein tumor.
Folia Med Cracov
April 2023
Department of General and Oncological Surgery, Medical University of Lodz, Lodz, Poland.
Article Synopsis
- The Buschke-Löwenstein tumor is a rare growth linked to HPV infection, primarily found in the perineal region.
- Although usually non-cancerous, there's a risk of the tumor becoming malignant.
- Early diagnosis and histopathological analysis are crucial for effective management of this condition.
Giant condyloma of Buschke-Löwenstein in a Netherton syndrome patient, successfully treated with cryotherapy and intravenous immunoglobulin.
J Dermatol
September 2023
Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Verrucous Carcinoma Arising in an Extended Giant Condyloma Acuminatum.
Skinmed
March 2023
Dermatology Department, Research Unit "Genodermatoses and cancers" LR12SP03, Habib Thameur Hospital, Tunis, Tunisia.
Article Synopsis
- A 43-year-old Tunisian man with a history of chronic hepatitis B presented with a large, foul-smelling genital mass that had been growing for over 10 years, severely affecting his quality of life.
- Physical examination indicated a cauliflower-like tumor surrounding his penis and linked to swollen lymph nodes in the groin area.
- Biopsy results showed signs of condyloma acuminatum along with atypical keratinocytes, indicating potential squamous cell carcinoma; he was referred for treatment including radiation and surgery.
Cutaneous Verrucous Carcinomas: A Review.
J Cutan Med Surg
April 2023
117972 Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Article Synopsis
- Verrucous carcinoma (VC) is a rare, slow-growing type of squamous cell carcinoma that is mainly found in mucosal areas and has low potential for spreading to other parts of the body, although it can also occur on the skin, particularly the feet.
- The diagnosis of cutaneous verrucous carcinoma (CVC) can be complicated, as it may resemble benign conditions or more aggressive cancers, which can lead to incorrect treatment approaches.
- This review covers the characteristics of CVC, including its causes and clinicopathologic features, and provides recommendations for diagnosis and treatment, emphasizing the importance of regular follow-up examinations after treatment.
Modified photodynamic therapy of vulvar giant condyloma acuminatum complicated by systemic lupus erythematosus: A case report.
Photodiagnosis Photodyn Ther
December 2022
Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University School of Medicine, 1278 Baode Road, Shanghai 200443, PR China. Electronic address:
Article Synopsis
- * Surgical removal is the typical treatment, but in the case of a patient with GCA, systemic lupus erythematosus, and low platelet counts, modified photodynamic therapy (M-PDT) was used instead.
- * After multiple M-PDT treatments, symptoms like pain and odor improved, but the wart size did not significantly change, and the patient ultimately passed away due to complications from lupus; however, M-PDT could still be considered for similar cases in the future.
The Pathogenesis of Giant Condyloma Acuminatum (Buschke-Lowenstein Tumor): An Overview.
Int J Mol Sci
April 2022
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR-1163, Necker Hospital for Sick Children, 75015 Paris, France.
Article Synopsis
- - Giant condyloma acuminatum (BLT) is a rare, aggressive tumor in the anogenital area, often linked to infection with low-risk HPVs like HPV-6 and -11, and known for its potential to recur.
- - The tumor is more common in individuals with immune deficiencies, whether primary (like DOCK8 or SPINK5 deficiency) or secondary (such as AIDS or after organ transplants), highlighting the importance of assessing immunity in affected patients.
- - Understanding the genetic and immunological factors involved in BLT can help improve treatment methods and management, indicating a need for further research into its underlying causes.
Buske-Lowenstein Tumor: A Rare Cause of Genital Warts.
Cureus
March 2022
Emergency Medicine, Envision Physician Services, Plantation, USA.
Article Synopsis
- The Buschke-Löwenstein tumor (BLT), also known as giant condylomata acuminata (GCA), is a rare tumor linked to human papillomavirus (HPV) that typically appears in the perianal region.
- A case is presented about a man who experienced instability and ringing in his ears, leading to an emergency assessment where symptoms of both condyloma acuminata and BLT were observed.
- While surgical excision and adjuvant treatments can effectively remove BLT, further research is necessary to fully understand the disease and its implications.
Giant anogenital tumor of Buschke-Löwenstein in a patient living with human immunodeficiency virus/acquired immunodeficiency syndrome: a case report.
J Med Case Rep
March 2022
Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon.
Article Synopsis
- Buschke-Löwenstein tumor is a rare but aggressive infection linked to HPV, often found in patients with HIV, characterized by large, ulcerated growths in the genital area.
- A case study highlighted a 21-year-old male with a significant tumor, multiple lesions, and co-infections of HIV and hepatitis B, which was diagnosed through biopsy.
- Treatment involved surgical intervention and antiviral therapy, but sadly, the patient's condition worsened due to an opportunistic infection, emphasizing the importance of regular screenings for other STIs in similar cases.
Clinical Conundrum: A Case of Cervical Giant Condyloma Acuminatum.
J Obstet Gynaecol Can
March 2022
Allan Blair Cancer Centre, Regina, SK.
Article Synopsis
- Giant condyloma acuminatum (GCA) is a benign growth linked to the human papilloma virus (HPV) that can appear like cancerous lesions but is rare on the cervix.
- A 35-year-old woman experienced abnormal uterine bleeding and had a cervical biopsy that initially indicated high-grade dysplasia, raising cancer concerns.
- A surgical procedure confirmed the diagnosis of GCA, emphasizing the need for quick biopsies when a cervical mass looks suspicious for cancer.
A rare case of self-healing giant condyloma acuminatum.
Dermatol Ther
January 2022
Department of Physiotherapy, Hospital of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.
Article Synopsis
- Giant condyloma acuminatum (GCA), also known as Buschke-Lowenstein tumor, is a rare tumor found in the anorectal area and external genitalia, linked to low-risk HPV types 6 or 11.
- GCA has a high recurrence rate of 66% and a significant risk of malignant transformation (56%) into conditions like squamous cell carcinoma.
- Treatment for GCA is challenging and self-healing is considered rare; however, a case of a 19-year-old female experiencing self-healing of GCA is reported.
Umbilical giant condyloma acuminatum.
Sex Transm Infect
September 2022
Unit of Dermatology, Livorno Hospital, and Melanoma & Skin Cancer Unit AVNO, Livorno, Italy.
Squamous Cell Carcinoma Arising from Perianal Buschke-Lowenstein Tumor (Giant Condyloma Acuminatum): Comprehensive Literature Review.
J Gastrointest Cancer
December 2022
Department of Surger, Faculty of Medicine, Inonu University, 44280, Malatya, Turkey.
Article Synopsis
- This study reviews existing literature on carcinoma associated with giant perianal condyloma acuminatum, emphasizing the need for increased awareness of its malignant potential.
- The research includes a new case study alongside a systematic literature review, identifying 55 articles involving 97 patients with various types of cancer arising from this condition.
- Findings reveal that while giant condyloma acuminatum is typically benign, it can lead to serious malignancies, stressing the importance of monitoring and management for patients with this tumor.
Buschke-Löwenstein tumour: a rare and challenging entity.
BMJ Case Rep
September 2021
General Surgery, Hospital da Luz, Vila Nova de Gaia, Portugal.
Article Synopsis
- Buschke-Löwenstein tumour (BLT) is a rare, locally aggressive skin tumor that can potentially become malignant, making its treatment challenging.
- A case study of a 57-year-old man revealed a giant perianal BLT that required surgical intervention, eventually leading to abdominoperineal resection after initial surgery failed due to sphincter involvement.
- The recommended treatment approach involves surgery as the first step, possibly combined with chemoradiation for better outcomes, accompanied by careful long-term monitoring.
Radical surgical management of perianal giant condyloma acuminatum of Buschke and Löwenstein: long-term results of 11 cases.
Ann Coloproctol
June 2023
Department of Surgery/Proctology, Memorial Ankara Hospital, Ankara, Turkey.
Article Synopsis
- The study focuses on the challenges of treating perianal Buschke-Löwenstein tumor (BLT), which presents as a large cauliflower-like growth that can infiltrate surrounding tissues and has a high chance of coming back after treatment.
- A total of 11 patients underwent wide local excision and V-Y flap reconstruction without using any additional treatment methods, with an average follow-up of over 50 months.
- Results showed that while some patients experienced minor issues like wound dehiscence, there were no serious complications, indicating that this surgical approach is effective for BLT.
[Giant condyloma acuminatum in pregnancy].
Gynecol Obstet Fertil Senol
February 2022
Service d'anatomie et cytologie pathologique, département de gynécologie-obstétrique et médecine de la reproduction, CHU Grenoble Alpes, 38700 La Tronche, France.
Article Synopsis
- - Buschke Lownestein's tumour is a rare, aggressive growth associated with HPV, known for its potential to recur even after treatment and its potential to invade surrounding tissues.
- - Treatment options remain debated, with surgical intervention often considered the best approach, especially complicated in pregnant patients due to the need to consider both maternal and fetal health.
- - Prevention strategies like HPV vaccination, sex education, and early treatment of lesions can enhance prognosis and reduce the recurrence of this condition.