Snakebites, a neglected public health concern: an analysis of distribution, trends and incidence of snakebite cases reported to health facilities in the Volta Region of Ghana, 2018-2023.

Background: Snakebite affects 5.4 million people annually, causing up to 2.7 million envenoming cases and 137 880 deaths.

Branding locally produced chicken in Ghana: An application of discrete choice experiment.

Branding is gradually becoming an essential component of successful agribusinesses and a significant motivation to boost modern agriculture. The study aimed to investigate broiler farmers' choices and preferences for branding locally produced chicken in Ghana. Primary data was collected from 562 broiler producers using a multistage sampling technique.

Emerging Therapeutic Modalities and Pharmacotherapies in Neuropathic Pain Management: A Systematic Review and Meta-Analysis of Parallel Randomized Controlled Trials.

Neuropathic pain (NP) is a chronic condition caused by abnormal neuronal excitability in the nervous system. Current treatments for NP are often ineffective or poorly tolerated. Hence, we reviewed the efficacy and safety of novel drugs or devices that target neuronal excitability in NP patients compared with placebo, sham, or usual care interventions.

Nanogap-Assisted SERS/PCR Biosensor Coupled Machine Learning for the Direct Sensing of in Food.

() is the primary risk factor in food safety. Herein, a nanogap-assisted surface-enhanced Raman scattering/polymerase chain reaction (SERS/PCR) biosensor coupled with a machine-learning tool was developed for the direct and specific sensing of S. aureus in milk.

Addressing the emerging threat of Oropouche virus: implications and public health responses for healthcare systems.

Oropouche fever is an increasingly significant health concern in tropical and subtropical areas of South and Central America, and is primarily spread by midge vectors. The Oropouche virus (OROV) was first identified in 1955 and has been responsible for numerous outbreaks, particularly in urban environments. Despite its prevalence, the disease is often under-reported, making it difficult to fully understand its impact.

Provincial distribution of unintended pregnancy and its associated factors in Sierra Leone.

Background: Unintended pregnancy is a significant public health concern in Sierra Leone, with far-reaching consequences for both mothers and children. This issue impacts individual well-being, strains healthcare systems, and hinders socioeconomic development. This study examined the prevalence and factors associated with unintended pregnancy in Sierra Leone.

Prevalence and determinants of full vaccination coverage according to the national schedule among children aged 12-35 months in Ghana.

Universal immunization of children against common vaccine-preventable diseases is crucial in reducing infant and child morbidity and mortality. Assessing the vaccination coverage is a key step to improve utilization and coverage of vaccines for under-five children. Accordingly, vaccination coverage according to the national schedule assesses the vaccination coverage of children aged 12-35 months.

Factors associated with vaccine default in Southern Ghana based on data from the RTSS malaria vaccine trial in Cape Coast.

Malaria has been a severe global and public health concern for the last couple of decades. Ghana, like many other countries in sub-Saharan Africa, is most affected by the disease, with children facing dire consequences. The recent introduction of the RTS, S malaria vaccine holds great potential in reducing malaria fatalities in children.

Acquisition of Fc-afucosylation of PfEMP1-specific IgG is age-dependent and associated with clinical protection against malaria.

Protective immunity to malaria depends on acquisition of parasite-specific antibodies, with Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) being one of the most important target antigens. The effector functions of PfEMP1-specific IgG include inhibition of infected erythrocyte (IE) sequestration and opsonization of IEs for cell-mediated destruction. IgG glycosylation modulates antibody functionality, with increased affinity to FcγRIIIa for IgG lacking fucose in the Fc region (Fc-afucosylation).

Neonicotinoid pesticides in African agriculture: What do we know and what should be the focus for future research?

This review provides a comprehensive overview of the direct and indirect effects of neonicotinoid pesticides (NEO-P) within African agricultural ecosystems and identifies research gaps, particularly in the monitoring and regulation of pesticide use. We observed a decline in the numbers of NEO-P studies conducted in Africa since 2019 with 40.7% of the countries reporting at least one study to date.

Dietary diversity and opportunistic infections among adults living with human immunodeficiency virus on antiretroviral therapy in Kumasi metropolis; a facility-based cross-sectional study.

Background: Despite advances in antiretroviral therapy (ART), people living with human immunodeficiency virus (HIV)/ acquired immunodeficiency syndrome (AIDS) continue to face heightened susceptibility to opportunistic infections (OIs). Adequate nutrition remains an essential factor that positively influences disease progression and the occurrence of OIs. In Ghana, no study has evaluated the association between dietary diversity and OI occurrence among adults with HIV.

Examining the risk mitigation strategies of farm households in Ghana: The role of community water resources.

Agricultural water is indispensable for fostering resilient and sustainable agricultural practices. However, empirical evidence regarding the relationship between community water resources (CWR) and risk mitigation behaviours among farm households remains scant. Utilising nationally-representative household survey data and geospatial information on household locations, we investigate how access to CWR influences crop diversification and sharecropping.

Identification of bacterial communities associated with needle mushroom () and its production environment.

is an important edible and medicinal mushroom widely cultivated in East Asia, with its quality and health strongly influenced by associated microbial communities. However, limited data exist on the bacterial communities associated with cultivation in Chinese farms. This study investigated bacterial communities associated with and its production environment using high-throughput 16S rRNA gene amplicon sequencing and culture-dependent methods.

Magnetic Janus SiO nanoparticles immobilized protease mutant T70I as a novel clarification agent for juice processing.

The juice processing industry offers several benefits, including promoting health and wellness through the delivery of beverages rich in nutrients. Nonetheless, the industry encounters significant challenges regarding new technologies for processing and preservation given that they can be costly and labor-intensive. In this study, magnetic Janus silica (SiO) nanoparticle which offers multifunctionality and high stability was synthesized and subsequently immobilized with a protease mutant T70I (T70I@MSNs) to serve as a clarifying agent in juice.

Effectiveness of physiotherapist-led exercise interventions for burn rehabilitation: A systematic review and meta-analysis.

Background: Exercise is utilised by physiotherapists to prevent complications and improve overall function and quality of life post-burn. However, the effect of physiotherapist-led exercise has not been comprehensively reviewed. Consequently, this study aimed to investigate the effectiveness of physiotherapy exercises for persons' post-burn.

Barriers and facilitators to implementing six monthly multi-month dispensing of antiretroviral therapy in two urban HIV clinics during the COVID-19 Era in Malawi.

Following the COVID-19 pandemic, the Malawi Government released a policy that promoted the scale-up of six-monthly multi-month dispensing (6-MMD) of antiretroviral therapy (ART) to people living with HIV in order to decrease congestion at health facilities and transmission of COVID-19. We evaluated the barriers and facilitators to implementing the scale-up of 6-MMD.We conducted a cross-sectional study and collected quantitative and qualitative data from 13 January 2022 to 5 February 2022 at two high-volume primary health facilities in urban Blantyre, Malawi.

Integration and acceptability of cervical cancer screening as part of postnatal care among women attending postnatal clinics in the Accra Metropolis, Greater Accra Region, Ghana.

Cervical cancer is a recognized preventable disease yet the fourth most common cancer among women globally. This study assessed the integration and acceptability of cervical cancer screening as part of routine sixth-week postnatal care among women attending a postnatal clinic. This was a cross-sectional descriptive study among 347 postpartum women who were attending their 6th-week postnatal visit.

Comparative analysis of 2 approaches to monitor countries' progress towards full and equal access to sexual and reproductive health care, information, and education in 75 countries: An observational validation study.

Background: Sustainable Development Goal (SDG) Indicator 5.6.2 is the "Number of countries with laws and regulations that guarantee full and equal access to women and men aged 15 years and older to sexual and reproductive health care, information, and education.

Dimensions of well-being and social harmony of older persons in Ghana: A secondary analysis of longitudinal survey data of the 2014/15 Study on Global Ageing and Adult Health (SAGE Wave 2).

Objectives: A crucial factor in healthy ageing is age-friendly environments for older persons. The opportunities that come with getting older as well as the safety of older persons are influenced by their social surroundings and overall well-being, yet, there is a dearth of research focus on this subject. This study examined the association between dimensions of well-being and the social harmony of older persons in Ghana.

Sleep problems and chronic conditions in single parents in Ghana: Serial mediating roles of health-related quality of life and functional limitations.

Objectives: Data on the association between sleep problems and chronic conditions among single parents in low- and middle-income countries (LMICs) are limited, and no study has, to date, reported the serial mediation effects of functional limitations and poor health-related quality of life (HRQoL) in this association. This study examines the extent to which functional limitations and poor HRQoL serially explain the link between sleep problems and chronic conditions among single parents in Ghana.

Methods: Data on 627 single mothers and fathers were obtained through a multi-stage stratified sampling technique.

Evidence-based approaches to cranial cerebrospinal fluid leaks in low- and middle-income countries: a systematic review of the literature.

Cerebrospinal fluid (CSF) leaks commonly occur due to trauma or surgical procedures. Here we review CSF leak diagnosis and management in Low- and Middle-Income Countries (LMICs). A systematic review of the CSF leak management in LMICs was conducted using PubMed, Google Scholar, Embase and Web of Science databases according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.

Cesarean section: One procedure, varied techniques. Detailed observations of 1013 first cesarean sections in a tertiary hospital in Ghana.

Objective: Cesarean sections (CS) are among the most performed surgical procedures in the world. Small variations in surgical techniques could have a significant impact on a global scale, for example, in postoperative complications. In the present study we aimed to observe and audit every single step used during first time CS.