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Sildenafil reduces postoperative adhesion formation in a rat uterine horn model.
Eur J Obstet Gynecol Reprod Biol
December 2007
Erciyes University, School of Medicine, Department of Obstetrics and Gynecology, Gevher Neshibe Hospital, 38039 Kayseri, Turkey.
Objective: The purpose of this experimental study was to evaluate the effect of oral sildenafil on postoperative adhesion formation in rats.
Study Design: Thirty-two Wistar Albino rats were subjected to standardized lesion by cauterization of the uterine horn and abrasion of the adjacent parietal peritoneum. They were randomized to receive sildenafil at a daily dose of 15 mg/kg, 7.