3 results match your criteria: "Geroscience and Rejuvenation Research Center - RESTORE[Affiliation]"
Comments on "Morphological, histological and biomechanical comparison of bone marrow aspirate concentrate, micro-fragmented adipose tissue and platelet-rich plasma in prevention of tendon adhesion".
J Plast Reconstr Aesthet Surg
March 2024
Geroscience and Rejuvenation Research Center - RESTORE, 4bis Av. Hubert Curien Bâtiment INCERE, 31100 Toulouse, France.
Synergistic Effects of Licorice Root and Walnut Leaf Extracts on Gastrointestinal Candidiasis, Inflammation and Gut Microbiota Composition in Mice.
Microbiol Spectr
April 2022
Geroscience and Rejuvenation Research Center (RESTORE), UMR 1301-Inserm 5070-CNRS EFS, Université P. Sabatier, Toulouse, France.
Candida albicans is an opportunistic pathogen that causes gastrointestinal (GI) candidiasis closely associated with intestinal inflammation and dysbiosis. Drug resistance, side effects of available antifungal agents, and the high recurrence of candidiasis highlight the need for new treatments. We investigated the effects of hydroethanolic extracts of licorice root (LRE) and walnut leaf (WLE) on GI colonization by C.
View Article and Find Full Text PDFToll-like receptor 4 selective inhibition in medullar microenvironment alters multiple myeloma cell growth.
Blood Adv
January 2022
Geroscience and Rejuvenation Research Center (RESTORE), Flames Team, INSERM 1301, UMR CNRS 5070, Univ. P. Sabatier, Toulouse, France.
Article Synopsis
- Bone marrow mesenchymal stromal cells (MSCs) in multiple myeloma (MM) are abnormal and promote tumor growth and drug resistance through higher expression of Toll-like receptor 4 (TLR4).
- Activation of TLR4 in MM MSCs enhances factors like CD54 and interleukin-6 (IL-6), which facilitate communication between MSCs and MM cells, impacting disease progression.
- Targeting TLR4 with antagonists shows promise in reducing MM cell growth support from MSCs and delaying disease progression in mouse models, suggesting a potential therapeutic strategy.