2 results match your criteria: "Germany. Electronic address: remi.peyronnet@universitaets-herzzentrum.de.[Affiliation]"
Cardiac mechanics and electrics: It takes two to tango.
Prog Biophys Mol Biol
November 2017
Institute for Experimental Cardiovascular Medicine, University Heart Centre Freiburg-Bad Krozingen, Medical School of the University of Freiburg, Germany. Electronic address:
Load-dependent effects of apelin on murine cardiomyocytes.
Prog Biophys Mol Biol
November 2017
Institute for Experimental Cardiovascular Medicine, University Heart Centre Freiburg · Bad Krozingen, Medical School of the University of Freiburg, Germany; Imperial College London, NHLI, Heart Science Centre, UK.
The apelin peptide is described as one of the most potent inotropic agents, produced endogenously in a wide range of cells, including cardiomyocytes. Despite positive effects on cardiac contractility in multicellular preparations, as well as indications of cardio-protective actions in several diseases, its effects and mechanisms of action at the cellular level are incompletely understood. Here, we report apelin effects on dynamic mechanical characteristics of single ventricular cardiomyocytes, isolated from mouse models (control, apelin-deficient [Apelin-KO], apelin-receptor KO mouse [APJ-KO]), and rat.
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