2 results match your criteria: "Germany. Electronic address: katja.odening@universitaets-herzzentrum.de.[Affiliation]"
Electro-mechanical (dys-)function in long QT syndrome type 1.
Int J Cardiol
January 2019
Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Freiburg, Germany; Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address:
Background: Prolonged repolarization is the hallmark of long QT syndrome (LQTS), which is associated with subclinical mechanical dysfunction. We aimed at elucidating mechanical cardiac function in LQTS type 1 (loss of I) and its modification upon further prolongation of the action potential (AP) by I-blockade (E-4031).
Methods: Transgenic LQT1 and wild type (WT) rabbits (n = 12/10) were subjected to tissue phase mapping MRI, ECG, and epicardial AP recording.
Another step towards a mechanism-based, subtype-specific therapy in long QT syndrome.
Int J Cardiol
July 2018
Department of Cardiology and Angiology I, Heart Center, University of Freiburg, Freiburg, Germany; Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address: