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Protection from Severe Influenza Virus Infections in Mice Carrying the Mx1 Influenza Virus Resistance Gene Strongly Depends on Genetic Background.

J Virol

October 2015

Department of Infection Genetics, Helmholtz Centre for Infection Research, Braunschweig, Germany University of Veterinary Medicine Hannover, Hannover, Germany University of Tennessee Health Science Center, Memphis, Tennessee, USA

Unlabelled: Influenza virus infections represent a serious threat to human health. Both extrinsic and intrinsic factors determine the severity of influenza. The MX dynamin-like GTPase 1 (Mx1) gene has been shown to confer strong resistance to influenza A virus infections in mice.

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