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Germany; Center for Systems Biology Dre... Publications | LitMetric

1,538,859 results match your criteria: "Germany; Center for Systems Biology Dresden CSBD[Affiliation]"

The Eger Rift subsurface is characterized by frequent seismic activity and consistently high CO concentrations, making it a unique deep biosphere ecosystem and a suitable site to study the interactions between volcanism, tectonics, and microbiological activity. Pulses of geogenic H during earthquakes may provide substrates for methanogenic and chemolithoautotrophic processes, but very little is currently known about the role of subsurface microorganisms and their cellular processes in this type of environment. To assess the impact of geologic activity on microbial life, we analyzed the geological, geochemical, and microbiological composition of rock and sediment samples from a 238 m deep drill core, running across six lithostratigraphic zones.

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Evaluation of factors associated with immunoglobulin, protein, fat and lactose concentrations in colostrum of dairy cows from Austria.

Acta Vet Scand

December 2024

Clinical Department for Farm Animals and Food System Science, Clinical Center for Ruminant and Camelid Medicine, University of Veterinary Medicine Vienna, Veterinaerplatz 1, Vienna, 1210, Austria.

Background: Calves rely on the passive transfer with immunoglobulins derived from colostrum. Currently, there is a lack of knowledge on colostrum management practices and colostrum quality on small scale family-owned dairy farms in Austria. The objectives of this study were to describe factors that are associated with immunoglobulin, protein, fat and lactose concentrations in dairy cow colostrum from the federal state of Salzburg.

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Life cycle and morphogenetic differentiation in heteromorphic cell types of a cosmopolitan marine microalga.

New Phytol

December 2024

Department of Ecology, Evolution and Behaviour, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, 9190401, Israel.

Gephyrocapsa huxleyi is a prevalent, bloom-forming phytoplankton species in the oceans. It exhibits a complex haplodiplontic life cycle, featuring a diploid-calcified phase, a haploid phase and a third 'decoupled' phase produced during viral infection. Decoupled cells display a haploid-like phenotype, but are diploid.

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A pipeline for validation of Serendipita indica effector-like sRNA suggests cross-kingdom communication in the symbiosis with Arabidopsis.

J Exp Bot

December 2024

Institute of Phytopathology, Research Centre for BioSystems, Land Use and Nutrition, Justus-Liebig-University Giessen, Heinrich-Buff-Ring 26, 35392 Giessen, Germany.

Bidirectional communication between pathogenic microbes and their plant hosts via small (s)RNA-mediated cross-kingdom RNA interference (ckRNAi) is a key element for successful host colonisation. Whether mutualistic fungi of the Serendipitaceae family, known for their extremely broad host range, use sRNAs to colonize plant roots is still under debate. To address this question, we developed a pipeline to validate the accumulation, translocation, and activity of fungal sRNAs in post-transcriptional silencing of Arabidopsis thaliana genes.

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Romantic Relationships Matter More to Men than to Women.

Behav Brain Sci

December 2024

Department of Experimental and Applied Psychology, VU Amsterdam, Amsterdam, Netherlands, and University of Cologne, Germany; www.paulvanlange.com.

Women are often viewed as more romantic than men, and romantic relationships are assumed to be more central to the lives of women than to those of men. Despite the prevalence of these beliefs, some recent research paints a different picture. Using principles and insights based on the interdisciplinary literature on mixed-gender relationships, we advance a set of four propositions relevant to differences between men and women and their romantic relationships.

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Nonlinear electron transport induced by polarized terahertz radiation is studied in two-dimensional tellurene at room temperature. A direct current, quadratic in the radiation's electric field, is observed. Contributions sensitive to radiation helicity and polarization orientation as well as polarization independent current are found.

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Background: Employment and relationship are crucial for social integration. However, individuals with major psychiatric disorders often face challenges in these domains.

Aims: We investigated employment and relationship status changes among patients across the affective and psychotic spectrum - in comparison with healthy controls, examining whether diagnostic groups or functional levels influence these transitions.

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Although ecosystem management and restoration are known to enhance carbon storage, limited knowledge of ecosystem-specific soil organic carbon (SOC) stocks and processes hinders the development of climate-ready, biodiversity-focused policies. Baseline SOC stocks data for specific ecosystems is essential. This paper aims to: (i) examine SOC stock variability across major grassy ecosystems in Brazil and (ii) discuss data limitations and applications.

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Objective: The care of patients with dysphonia will change due to the growing shortage of specialists, demographic change, and digitalization. To counteract the associated problems in patient care, the LAOLA app demonstrator is to be developed. In the future, patients will receive exercise videos for their training from their treating speech and language pathologist (SLP) via LAOLA.

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Oncological Benefits of Extended Pelvic Lymph Node Dissection: More Fog or Clarity to the Debate?

Eur Urol

December 2024

Martini-Klinik Prostate Cancer Center, University Hospital Hamburg Eppendorf, Hamburg, Germany; Department of Urology, University Hospital Hamburg-Eppendorf, Hamburg, Germany; Department of Urology, Koc University Hospital, Istanbul, Turkey. Electronic address:

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A scoping review of participatory approaches in child maltreatment research across Europe.

Child Abuse Negl

December 2024

National Competence Center Barnafrid, Linköping University, Linköping, Sweden; Department of Child and Adolescent Psychiatry and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.

Background: Participatory approaches in child maltreatment (CM) research increasingly focus on involving children, youth, and adults as co-researchers. However, little is known about their use in Europe.

Objective: To review the European literature on participatory approaches in CM research.

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Background: The Paediatric Rheumatology International Trials Organisation (PRINTO) recently undertook an effort to better harmonize the pediatric and adult arthritis criteria. These provisional criteria are being refined for optimal performance. We aimed to investigate differences between patients who did and did not fulfill these PRINTO criteria amongst youth diagnosed with juvenile spondyloarthritis (SpA) that met axial juvenile SpA (axJSpA) classification criteria.

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Background: There is a current fashion for the use of methacrylate-containing nail cosmetics that can induce allergic contact dermatitis. European Union (EU) legislation was introduced in 2021 that had the aim of preventing its development.

Objectives: To assess prevalence and exposures causing contact allergy to 2-hydroxyethyl methacrylate (HEMA) prior to and following implementation of the legislation.

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Epidemic infections and spreading antibiotic resistance require diagnostic tests that can be rapidly adopted. To reduce the usually time-consuming adaptation of molecular diagnostic tests to changing targets, we propose the novel approach of a repurposable sensing electrode functionalization with a universal, target-independent oligonucleotide probe. In the liquid phase covering the electrode, the target sequence is amplified by MD LAMP (mediator-displacement loop-mediated isothermal amplification) releasing a generic methylene blue-labeled mediator, which specifically hybridizes to the solid-phase probe.

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E3 ubiquitin ligases have been linked to developmental diseases including autism, Angelman syndrome (UBE3A), and Johanson-Blizzard syndrome (JBS) (UBR1). Here, we report variants in the E3 ligase UBR5 in 29 individuals presenting with a neurodevelopmental syndrome that includes developmental delay, autism, intellectual disability, epilepsy, movement disorders, and/or genital anomalies. Their phenotype is distinct from JBS due to the absence of exocrine pancreatic insufficiency and the presence of autism, epilepsy, and, in some probands, a movement disorder.

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Molecular architectures of centrosomes in C. elegans embryos visualized by cryo-electron tomography.

Dev Cell

December 2024

Structural and Computational Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany; Cell Biology and Biophysics Unit, EMBL, 69117 Heidelberg, Germany. Electronic address:

Centrosomes organize microtubules that are essential for mitotic divisions in animal cells. They consist of centrioles surrounded by pericentriolar material (PCM). Questions related to mechanisms of centriole assembly, PCM organization, and spindle microtubule formation remain unanswered, partly due to limited availability of molecular-resolution structural data inside cells.

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Retraction notice "to Loss of mitochondrial adaptation associates with deterioration of mitochondrial turnover and structure in metabolic dysfunction-associated steatotic liver disease" [Metabolism 151 (2024) 155762].

Metabolism

December 2024

Department of Endocrinology and Diabetology, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University, Düsseldorf, Germany; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research at Heinrich-Heine-University, Düsseldorf, Germany; German Center for Diabetes Research, Partner Düsseldorf, Neuherberg, Germany.

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Reproduction traits are important factors determining the efficiency of any sheep production system. This study evaluates the age at first lambing (AFL), lambing interval (LI), litter weight at birth (LBWT), litter weight at weaning (LWWT), birth weight of ewe (EBWT) and weaning weight of ewes (EWWT) in a crossbreeding program between the Red Maasai (RRRR) and Dorper sheep and their crosses, 75% Dorper and 50% Dorper (DDRR) breeds. All the traits significantly (P < 0.

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With the beginning of the COVID-19 pandemic, wastewater-based epidemiology (WBE), which according to Larsen et al. (2021), describes the science of linking pathogens and chemicals found in wastewater to population-level health, received an enormous boost worldwide. The basic procedure in WBE is to analyse pathogen concentrations and to relate these measurements to cases from clinical data.

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Old but not ancient: Rock-leached organic carbon drives groundwater microbiomes.

Sci Total Environ

December 2024

Aquatic Geomicrobiology, Institute of Biodiversity, Friedrich Schiller University, Jena, Germany; Cluster of Excellence Balance of the Microverse, Friedrich Schiller University Jena, Jena, Germany; German Center for Integrative Biodiversity Research (iDiv) Halle-Jena_Leipzig, Germany. Electronic address:

More than 90% of earth's microbial biomass resides in the continental subsurface, where sedimentary rocks provide the largest source of organic carbon (C). While many studies indicate microbial utilization of fossil C sources, the extent to which rock-organic C is driving microbial activities in aquifers remains largely unknown. Here we incubated oxic and anoxic groundwater with crushed carbonate rocks from the host aquifer and an outcrop rock of the unsaturated zone characterized by higher organic C content, and compared the natural abundance of radiocarbon (C) of available C pools and microbial biomarkers.

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Introduction: The positive impact of prunes on body measurements and blood pressure has been suggested in previous research.

Purpose: The purpose of this extensive meta-analysis and systematic review was to examine the effects of adult consumption of prunes on anthropometric parameters and blood pressure.

Methods: To identify relevant randomized controlled trials (RCTs) (till August 9th, 2024), databases from ISI Web of Science, Scopus, and PubMed/Medline were searched.

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Injection artifacts in odorant analysis by gas chromatography.

J Chromatogr A

December 2024

Technical University of Munich, TUM School of Natural Sciences, Department of Chemistry, Lichtenbergstraße 4, 85748 Garching, Germany; Leibniz Institute for Food Systems Biology at the Technical University of Munich (Leibniz-LSB@TUM), Lise-Meitner-Straße 34, 85354 Freising, Germany. Electronic address:

Odor-active compounds are major quality parameters in food and other consumer products. In the analysis of odorants, gas chromatography (GC) plays a dominant role and is particularly indispensable for odorant screening by GC-olfactometry (GC-O). Whereas artifact formation during workup before GC analysis has been widely discussed, artifact formation during GC injection has not been adequately addressed so far.

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An international expert survey on the worldwide digitalization in psychiatry: Global findings from the WPA survey.

Asian J Psychiatr

December 2024

WHO Collaborating Centre DEU-131, LVR-Klinikum Düsseldorf, Department of Psychiatry, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.

Background: The World Psychiatric Association (WPA) Working Group on Digital Psychiatry aims to digitally supplement, support and improve mental health and care literacy, acceptance and accessibility across WPA member countries and National Psychiatric Associations (NPAs). To help with this goal, the present study was set to explore first the global status of digital mental health and care across NPAs METHODS: An international expert survey on the digitalization level across all 145 WPA NPAs was electronically distributed through Qualtrics. Descriptive statistics were carried out on the global dataset.

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Stone selection by wild chimpanzees shares patterns with Oldowan hominins.

J Hum Evol

December 2024

Department of Pedagogy, Chubu Gakuin University, Gifu, 504-0837, Japan; College of Life Science, Northwest University, Xi'an, 710069, China.

The use of broad tool repertoires to increase dietary flexibility through extractive foraging behaviors is shared by humans and their closest living relatives (chimpanzees, Pan troglodytes). However, comparisons between tool use in ancient human ancestors (hominins) and chimpanzees are limited by differences in their toolkits. One feature shared by primate and hominin toolkits is rock selection based on physical properties of the stones and the targets of foraging behaviors.

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