Research on recognition of slippery road surface and collision warning system based on deep learning.

Aiming at the problems of slow detection speed, large prediction error and weak environmental adaptability of current vehicle collision warning system, this paper proposes a recognition method of slippery road surface and collision warning system based on deep learning. Firstly, this paper uses the on-board camera to monitor the environment and road conditions in front of the vehicle in real time, and a residual network model FS-ResNet50 is proposed, which integrated SE attention mechanism and multi-level feature information based on the traditional ResNet50 model. The FS-ResNet50 model is used to identify the slippery states of the current road, such as wet and snowy.

Good vibes for the brain - Placebo versus real vibration in patients with chronic neck pain: A randomized cross-over study.

Background: Neck muscle vibration decreases pain and improves sensorimotor impairments in patients with chronic neck pain. However, the impact of placebo on these effects are still unclear.

Objective: The aim was to evaluate the effect of neck muscle vibration compared to placebo neck muscle vibration in patients with chronic neck pain.

Impact of statistical poly(propylene co-ethylene) on the thermo-mechanical properties of high-density polyethylene.

A series of high-density polyethylene and a statistical copolymer of poly(propylene-co-ethylene) blends in a wide range, namely (0, 10, 20, 30, 40, 50, 60,70, 80, 90, 100) abbreviated as HDPE/VM were systematically investigated by using a rheometer, differential scanning calorimetry (DSC) measurements, polarized optical microscopy (POM) and tensile tests. Rheometer results show that adding VM decreases dynamic viscosity, storage, and loss modulus. Han plot shows that HDPE and VM are compatible and miscible in the range from 20 to 60 VM % in the molten state.

Trust and distrust in public governance settings: Conceptualising and testing the link in regulatory relations.

The relationship between trust and distrust in public governance is still an open question. In the literature, three different perspectives on how trust and distrust are related are intensively debated: (1) trust and distrust as two ends of the same conceptual continuum; (2) trust and distrust as opposites, but with neutral ground in between; and (3) trust and distrust as related, yet distinct concepts. Employing a new measure for distrust and by using perceptual data on trust and distrust in regulatory agencies from multiple types of stakeholders in nine countries and three sectors, this article shows that high trust and high distrust can co-exist at the same time, and that trust and distrust are negatively correlated only to a limited extent.

Leukemic B cells expression of CD200 and Leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1, CD305) in Chronic Lymphocytic Leukemia patients in relation to Treg frequency.

Background: Chronic lymphocytic leukemia (CLL) is characterized by a wide range of tumor-induced immune alterations. Regulatory T cells (Treg) play a central role in these immune responses. CD200 and Leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1, CD305) are inhibitory markers said to be involved in Treg immune response.

N-[4-(Benzyloxy)-3-methoxybenzyl)]adamantane-1-amine (DZH2), a dual CCR5 and CXCR4 inhibitor as a potential agent against triple negative breast cancer.

DZH2, a dual inhibitor of the chemokine receptors CCR5 and CXCR4, was discovered from virtual screening for CCR5 antagonists. In specific Ca chemokine signaling assays, DZH2 displayed low micromolar IC values at both chemokine receptors. Its binding to intracellular allosteric binding sites of CCR5 and CXCR4 was confirmed by MD simulations and binding free-energy calculations.

Frequency selective metasurface based radio frequency glucose sensor with a periodic array of meta cells.

Nowadays, the operating principle of most of the experimental electromagnetic glucose sensors is based on the effect of an anomalous dispersion caused by a direct contact between an object under test and a two-dimensional metasurface. Due to the repeated uses, the metasurface will be subjected to a chemical attack over time. To avoid this problem, this work proposes a novel glucose sensor that is equipped with an interfacial dielectric layer of 0.

Key genes and pathways in the molecular landscape of pancreatic ductal adenocarcinoma: A bioinformatics and machine learning study.

Pancreatic ductal adenocarcinoma (PDAC) is recognized for its aggressive nature, dismal prognosis, and a notably low five-year survival rate, underscoring the critical need for early detection methods and more effective therapeutic approaches. This research rigorously investigates the molecular mechanisms underlying PDAC, with a focus on the identification of pivotal genes and pathways that may hold therapeutic relevance and prognostic value. Through the construction of a protein-protein interaction (PPI) network and the examination of differentially expressed genes (DEGs), the study uncovers key hub genes such as CDK1, KIF11, and BUB1, demonstrating their substantial role in the pathogenesis of PDAC.

Effects of functional groups on ESIPT and antioxidant activity of apigenin: A non-existent enol* state fluorescein.

The development and enhancement of antioxidant drugs, which are aimed at mitigating DNA damage, mutations, and cancer, are of paramount significance in the biomedical sphere. In recent years, antioxidant drug molecules with photoluminescence have sprung up like mushrooms. Apigenin (AP), characterized by its distinctive property of excited state intramolecular proton transfer (ESIPT), plays a pivotal role in mediating antioxidant and anticancer activities.

Effects of the Amyotrophic Lateral Sclerosis-related Q108P Mutation on the Structural Ensemble Characteristics of CHCHD10.

Introduction: The Q108P pathological variant of the mitochondrial Coiled-Coil-Helix-- Coiled-Coil-Helix Domain-Containing Protein 10 (CHCHD10) has been implicated in amyotrophic lateral sclerosis (ALS). Both the wild-type and CHCHD10Q108P proteins exhibit intrinsically disordered regions, posing challenges for structural studies with conventional experimental tools.

Method: This study presents the foundational characterization of the structural features of CHCHD10Q108P and compares them with those of the wild-type counterpart.

LncPepAtlas: a comprehensive resource for exploring the translational landscape of long non-coding RNAs.

Long non-coding RNAs were commonly viewed as non-coding elements. However, they are increasingly recognized for their ability to be translated into proteins, thereby playing a significant role in various cellular processes and diseases. With developments in biotechnology and computational algorithms, a range of novel approaches are being applied to investigate the translation of long non-coding RNA (lncRNAs).

Advancements in current one-size-fits-all therapies compared to future treatment innovations for better improved chemotherapeutic outcomes: a step-toward personalized medicine.

The development of therapies followed a generalized approach for a long time, assuming that a single treatment could effectively address various patient populations. However, recent breakthroughs have revealed the limitations of this one-size-fits-all paradigm. More recently, the field of therapeutics has witnessed a shift toward other modules, including cell therapies, high molecular weight remedies, personalized medicines, and gene therapies.

Modular soft pneumatic actuator mimics elephant trunk locomotion.

Robots support and facilitate tasks in all life fields. Soft robots specifically have the advantages of inherent compliance, safe interaction and flexible deformability. Soft pneumatic network (Pneu-Net) is a soft pneumatic actuator (SPA) composed of network of chambers that is actuated by pneumatic power.

Reconstructing suspended sediment concentrations in the Mekong River Basin via semi-supervised-based deep neural networks.

The Mekong River Basin (MRB) is crucial for the livelihoods of over 60 million people across six Southeast Asian countries. Understanding long-term sediment changes is crucial for management and contingency plans, but the sediment concentration data in the MRB are extremely sporadic, making analysis challenging. This study focuses on reconstructing long-term suspended sediment concentration (SSC) data using a novel semi-supervised machine learning (ML) model.

OncomiR-181a promotes carcinogenesis by repressing the extracellular matrix proteoglycan decorin in hepatocellular carcinoma.

Background: Proteoglycans are important tumor microenvironment extracellular matrix components. The regulation of key proteoglycans, such as decorin (DCN), by miRNAs has drawn attention since they have surfaced as novel therapeutic targets in cancer. Accordingly, this study aimed at identifying the impact of miR-181a in liver cancer and its regulatory role on the extracellular matrix proteoglycan, DCN, and hence on downstream oncogenes and tumor suppressor genes.

Evaluation of Treatment Protocols in Surgically Assisted Rapid Maxillary Expansion by Finite Element Analysis.

: Transverse maxillary deficiency is an important maxillary anomaly that is very common in society and remains current in orthodontics. The maxillary expansion has been used in treatment for a long time. While maxillary expansion can be performed with rapid maxillary expansion in young adults, it is performed with surgically assisted rapid maxillary expansion (SARME) in individuals who have reached skeletal maturity.