Correction: Scalable synthesis and structural characterization of reversible KLK6 inhibitors.

[This corrects the article DOI: 10.1039/D2RA04670A.].

Scalable synthesis and structural characterization of reversible KLK6 inhibitors.

Scalable asymmetric syntheses of two kallikrein-related protease 6 (KLK6) inhibitors are reported. The inhibitors are assembled by linking enantiomerically enriched fragments amide bond formation, followed by conversion of a cyano group to an amidine. One fragment, an amine, was prepared using the Ellman auxiliary, and a lack of clarity in the literature regarding the stereochemical outcome of this reaction was solved X-ray crystallographic analysis of two derivatives.