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Georgetown University Hospital.[Affilia... Publications | LitMetric

5,871 results match your criteria: "Georgetown University Hospital.[Affiliation]"

High risk and low incidence diseases: Lisfranc injury.

Am J Emerg Med

November 2024

Department of Emergency Medicine, Brooke Army Medical Center, Fort Sam Houston, TX, USA. Electronic address:

Article Synopsis
  • Lisfranc injuries, while uncommon, are often misdiagnosed and can lead to serious long-term issues if not treated promptly.
  • These injuries can range from minor subluxations to severe fractures and may present with midfoot pain, swelling, or bruising, making immediate diagnosis crucial.
  • Advanced imaging like CT scans is essential when initial x-rays are inconclusive, and collaboration with orthopedic surgery is necessary for proper management.
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Background: Subarachnoid hemorrhage (SAH) following endovascular thrombectomy (EVT) is a poorly understood phenomenon, and whether it is associated with clinical detriment is unclear.

Methods: This was an explorative analysis of a national database of real-world hospitalizations in the United States. Patients who underwent EVT were included.

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Bilateral Proximal Humerus Lesser Tuberosity Avulsions in an Adolescent Patient: A Case Report.

JBJS Case Connect

July 2024

Department of Orthopaedic Surgery and Sports Medicine, Children's National Hospital, Washington, District of Columbia.

Case: Fourteen-year-old boy presented with bilateral proximal humerus lesser tuberosity avulsions after swinging between 2 desks. Injuries were not visualized on radiographs but identified on magnetic resonance imaging. He underwent bilateral open reduction and internal fixation of the bony avulsions.

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The incidence of jejunogastric intussusception (JGI) after gastric surgery is 0.1%. We report a case of JGI after pancreaticoduodenectomy in a patient with HIV.

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Progress in the Search for an Effective Resorbable Embolic Material for Uterine Fibroid Embolization.

Radiology

September 2024

From the Department of Radiology, Georgetown University School of Medicine, Medstar Georgetown University Hospital, 3800 Reservoir Rd NW, CG 201, Washington, DC 20007.

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Background: Robot-assisted techniques are increasingly integrated into the field of spine surgery, with the potential benefits of increased accuracy and reduced radiation exposure. The objective of this study was to describe the technique of minimally invasive robot-assisted direct pars repair with 2 case illustrations.

Observations: An 18-year-old male and a 42-year-old male, both with bilateral L5 spondylolysis, underwent successful minimally invasive L5 direct pars repairs with robotic assistance after conservative measures failed, and their cases are presented herein.

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Objective: To estimate the number needed to treat and cost per additional responder for atogepant and rimegepant versus placebo for the preventive treatment of episodic migraine (EM) in the United States.

Background: Migraine has an enormous impact on a person's daily activities and quality of life, and results in significant clinical and economic burden to both individuals and society. It is important to understand the comparative efficacy and economic value of oral calcitonin gene-related peptide receptor antagonists (gepants) for preventive treatment of EM.

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Article Synopsis
  • Rheumatologic disease-associated hemophagocytic lymphohistiocytosis (HLH) is a rare and serious condition that may arise from underlying autoimmune diseases; real-world data on the use of the monoclonal antibody emapalumab for treatment is limited.
  • A study called REAL-HLH reviewed medical records from 33 hospitals to evaluate the use and outcomes of emapalumab in patients with rheumatologic disease-associated HLH, finding that 14.3% of 105 patients studied had this subtype.
  • Results showed that emapalumab treatment led to improvements in key laboratory parameters, significantly reduced glucocorticoid use, and had a high survival rate, indicating its potential effectiveness in managing
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Article Synopsis
  • Purtscher's and Purtscher-like retinopathies are rare eye conditions characterized by specific visual symptoms and potentially severe outcomes, primarily linked to trauma or systemic diseases such as systemic lupus erythematosus.
  • A study analyzed 114 articles covering 168 cases, finding that trauma was the leading cause in nearly 40% of patients, and the average age of patients was around 34.6 years.
  • Most patients experienced bilateral vision problems, with symptoms like blurred vision, cotton-wool spots, and Purtscher flecken being common; overall, about 53% had a favorable visual prognosis.
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Transorbital Approach Clipping of Middle Cerebral Artery Aneurysm: A Virtual Reality Morphometric Anatomic Study.

World Neurosurg

November 2024

Department of Neurologic Surgery and Brain Repair, University of South Florida, Tampa, Florida, USA; Division of Neurosurgery, Fleming Neuroscience Institute, Lehigh Valley Network, Allentown, Pennsylvania, USA.

Background: The transorbital approach (TOA) has a unique advantage to the more common lateral approaches as it provides direct access to the anterior middle fossa and medial sylvian fissure (SF) without significant dissection or retraction. However, when to use the TOA for surgical treatment of middle cerebral artery (MCA) aneurysms remains unclear. This study details the feasibility of clipping unruptured MCA aneurysms via the TOA by highlighting the anatomic features that either facilitate or hinder the approach.

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Article Synopsis
  • This study analyzes the outcomes of two surgical techniques - peritoneal flap vaginoplasty (PFV) and intestinal segment vaginoplasty (ISV) - in transgender or non-binary patients who experienced failed penile inversion vaginoplasty (PIV).
  • Both methods aim to restore neovaginal depth and sexual function, with 21 patients undergoing PFV and 24 patients undergoing ISV reported between December 2018 and April 2023.
  • The results show that while PFV had a higher rate of long-term complications like vaginal stenosis, ISV exhibited lower complications overall, suggesting ISV may be a more favorable option for revising vaginal stenosis after failed PIV.
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Article Synopsis
  • A study was conducted to compare robotic minor liver resections (RMLR) with laparoscopic minor liver resections (LMLR) in patients undergoing surgery on the anterolateral liver segments.
  • The analysis included over 10,000 patients and employed propensity score matching to balance the groups for accuracy in comparisons.
  • Results indicated RMLR had benefits like less blood loss, lower major morbidity, and shorter hospital stays than LMLR, although the difference in 30-day readmission rates suggested RMLR may have some drawbacks.
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Article Synopsis
  • Medication-related osteonecrosis of the temporal bone is uncommon and linked to certain medications, specifically anti-resorptive and tyrosine-kinase inhibitors, with new cases being reported.* -
  • Three case studies highlight patients with osteonecrosis of the external auditory canal (EAC), with treatments ranging from conservative management to surgical reconstruction, showing varying success.* -
  • The findings suggest that these medications can disrupt bone remodeling, and when standard therapies fail, surgical intervention may be necessary for symptom relief.*
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Introduction: Although the ACGME and other accrediting organizations are increasingly emphasizing the importance of clinical learning environments that value diversity, equity, and inclusion, faculty development surrounding behavioral skills that promote inclusivity in the learning environment still needs cultivation. We designed a virtual longitudinal faculty development curriculum focused on direct observation, feedback, and practice of behavioral skills to acknowledge and address microaggressions in the learning environment.

Methods: We used Kern's six steps of curriculum development to create four voluntary virtual workshops offered twice throughout the academic year, with topics including: (1) recognizing and naming microaggressions, (2) apologizing when harm has been experienced, (3) setting expectations surrounding microaggressions, and (4) debriefing microaggressions.

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Background: HLA-DQ mismatch has been identified as a predictor of de novo donor-specific HLA antibody formation and antibody-mediated rejection. There are insufficient data to guide the incorporation of DQ mismatch into organ allocation decisions.

Methods: We used a retrospective longitudinal cohort of adult living donor kidney transplant recipients from 11 centers across the United States for whom high-resolution class II typing was available.

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Purpose: The current commonly used metrics for evaluating the quality of auto-segmented contours have limitations and do not always reflect the clinical usefulness of the contours. This work aims to develop a novel contour quality classification (CQC) method by combining multiple quantitative metrics for clinical usability-oriented contour quality evaluation for deep learning-based auto-segmentation (DLAS).

Methods And Materials: The CQC was designed to categorize contours on slices as acceptable, minor edit, or major edit based on the expected editing effort/time with supervised ensemble tree classification models using 7 quantitative metrics.

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Management of Cholesteatoma: Hearing Rehabilitation.

Otolaryngol Clin North Am

February 2025

Department of Otolaryngology-Head & Neck Surgery, Medstar Georgetown University Hospital, Washington, DC, USA.

Surgical treatment of cholesteatoma requires a highly individualized approach, balancing disease eradication with hearing preservation, and necessitates thorough patient counseling on expected auditory outcomes and options for rehabilitation. The choice between canal wall up and canal wall down mastoidectomy can influence hearing outcomes. Hearing rehabilitation options following cholesteatoma surgery include air- and bone-conduction devices and are individualized for the patient.

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From Echoes to Disruption: US from Diagnostic Imaging to Precision Therapeutic Modality.

Radiology

September 2024

From the Division of Interventional Radiology, Department of Radiology, MedStar Georgetown University Hospital, 3800 Reservoir Rd NW, CCC Bldg, Rm CG225, Washington, DC 20007 (N.N.); Georgetown University School of Medicine, Washington, DC (N.N.); Lombardi Comprehensive Cancer Center, Washington, DC (N.N.); and Division of Vascular and Interventional Radiology, Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins School of Medicine, Baltimore, Md (C.G.).

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Spontaneous pneumomediastinum: A comprehensive review of diagnosis and management.

Intractable Rare Dis Res

August 2024

Division of Pulmonary, Critical Care and Sleep Medicine, Northwell Health, New Hyde Park, NY, USA.

Pneumomediastinum is a rare condition defined by the presence of air in the mediastinum. In the absence of traumatic injury, iatrogenic injury, or clear etiology, it is called spontaneous pneumomediastinum (SPM). Spontaneous pneumomediastinum most commonly occurs in younger individuals and has a self-limiting course with a good outcome.

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Predicting Long-Term Clinical Outcomes of Patients With Recurrent Pericarditis.

J Am Coll Cardiol

September 2024

Center for the Diagnosis and Treatment of Pericardial Diseases, Section of Cardiovascular Imaging, Department of Cardiovascular Medicine, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA. Electronic address:

Article Synopsis
  • Recurrent pericarditis (RP) is a challenging condition with no established model for predicting patient outcomes, despite prior studies on clinical remission.
  • A risk stratification model was created using data from 365 patients to predict long-term outcomes, focusing on clinical remission defined as stopping all medications with symptoms resolved.
  • The model identified key factors, achieved a C-index of 0.800 for prediction accuracy, and effectively categorized patients into high, intermediate, and low-risk groups, improving individualized treatment decisions for RP.
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Objective: The objective is to comprehensively classify the types, topics and populations represented in the published lacrosse literature.

Design: Mapping review. Protocol registration at Open Science Framework (https://osf.

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Article Synopsis
  • T-cell large granular lymphocytic (T-LGL) leukaemia is often linked to autoimmune disorders, with about one-third of patients also having rheumatoid arthritis (RA).
  • A notable portion of RA patients display clonal T-cell patterns, indicating a possible connection between the two conditions.
  • This text discusses a specific case of a patient with RA who was evaluated for low white blood cell count and enlarged spleen, ultimately leading to a diagnosis of T-LGL leukaemia.
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