154 results match your criteria: "George Mason University. Fairfax[Affiliation]"

Objective: The November through January holiday period is often thought to produce weight gain, coined "holiday weight gain." While this trend has been documented among early to midlife adults, it is less certain whether college students experience similar levels of weight gain during this period, as they undergo lifestyle changes (e.g.

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This work aims to identify a mechanism of interaction between soil moisture (SM) state and the incidence of weakly forced synoptic scale MCS events during boreal summer by performing a sensitivity study using the Weather Research and Forecasting (WRF) model over the US Great Plains. A uniformly dry SM patch at a 5° × 5° scale is centered at the point of a documented MCS initiation to observe spatiotemporal changes of the simulated MCS events, totaling 97 cases between 2004 and 2017. A storm-centered composite analysis of SM at the location of simulated MCS events depicted SM heterogeneity [O(100) km] structured as significantly drier soils to the southwest (SW) transitioning to wetter soils northeast (NE) of the mean simulated initiation.

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This paper proposes algorithms for estimating parameters in Earth System Models (ESMs), specifically focusing on simulations that have not yet achieved statistical equilibrium and display climate drift. The basic idea is to treat ESM time series as outputs of an autoregressive process, with parameters that depend on those of the ESM. The maximum likelihood estimate of the parameters and the associated uncertainties are derived.

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Identifying sources of air pollution exposure is crucial for addressing their health impacts and associated inequities. Researchers have developed modeling approaches to resolve source-specific exposure for application in exposure assessments, epidemiology, risk assessments, and environmental justice. We explore six source-specific air pollution exposure assessment approaches: Photochemical Grid Models (PGMs), Data-Driven Statistical Models, Dispersion Models, Reduced Complexity chemical transport Models (RCMs), Receptor Models, and Proximity Exposure Estimation Models.

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To achieve long term success of orthopedic implants, it is critical to have a successful integration of bone and implant material. To accomplish this, various surface modifications have been investigated in research. Even though titania nanotubes and copper have individually demonstrated successful stem cell adhesion, proliferation and differentiation, these modifications have not yet been investigated together.

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US public health surveillance, reimagined.

Learn Health Syst

October 2024

Department of Health Administration and Policy College of Public Health, George Mason University Fairfax VA USA.

Introduction: This study presents two novel concepts for standardizing electronic health records (EHR)-based public health surveillance through utilization of existing informatics methods and data platforms.

Methods: Drawing from the collective experience in applied epidemiology, health services research and health informatics, the author presents a vision for an alternative path to public health surveillance by repurposing existing tools and resources, such as (1) computable phenotypes which have already been created and validated for a variety of chronic diseases of interest to public health and (2) large data platforms/collaboratives, such as All of Us Research Program and National COVID Cohort Collaborative. Opportunities and challenges are discussed regarding EHR-based chronic disease surveillance, as well as the concept of phenotype definitions and large data platforms reuse for public health needs.

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Current and near future climate policy will fundamentally influence the integrity of ecological systems. The Neotropics is a region where biodiversity is notably high and precipitation regimes largely determine the ecology of most organisms. We modeled possible changes in the severity of seasonal aridity by 2100 throughout the Neotropics and used birds to illustrate the implications of contrasting climate scenarios for the region's biodiversity.

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Article Synopsis
  • A new tool has been developed to effectively smooth and model irregular point clouds, which can come from various sources, with a focus on solid modeling.
  • The technique utilizes multivariate splines over triangulation to improve the quality of the data by reducing noise and blur, while also enabling a multi-resolution reconstruction.
  • The methodology has been theoretically verified, showcasing optimal convergence rates and includes a bootstrapping approach to measure estimator uncertainty, outperforming traditional smoothing methods in real-world applications.
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  • The study examines how different interrogation methods (like accusatorial vs. information-gathering) influence the rates of true and false confessions from mock criminal suspects, aiming to find an optimal approach that encourages honest confessions while reducing false ones.
  • Researchers conducted a systematic review, updating previous work by assessing data from 27 articles and 81 effect sizes, primarily involving college students in the U.S., to analyze the impact of interrogation techniques.
  • They employed rigorous methods for data selection and analysis, including network meta-analysis, and found that authors generally followed good research practices, such as double-blind procedures and transparent reporting.
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  • A small working group was formed to modernize the Methodological Expectations for Campbell Collaboration Intervention Reviews (MECCIR) based on feedback indicating that the previous version was too lengthy and challenging to use.
  • The goal was to create a more concise and relevant checklist that includes guidance for both conducting and reporting reviews, applicable to various types including quantitative non-intervention reviews.
  • The development process included multiple meetings to discuss and refine the checklist, aligning it with existing standards, and incorporated feedback from Campbell members to ensure it was comprehensive yet user-friendly.
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In () and (), the methylerythritol phosphate (MEP) pathway is responsible for isoprene synthesis. This pathway and its products are vital to bacterial/parasitic metabolism and survival, and represent an attractive set of drug targets due to their essentiality in these pathogens but absence in humans. The second step in the MEP pathway is the conversion of 1-deoxy-d-xylulose-5-phosphate (DXP) to MEP and is catalyzed by 1-deoxy-d-xylulose-5-phosphate reductoisomerase (DXR).

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The tree-like morphology of neurons and glia is a key cellular determinant of circuit connectivity and metabolic function in the nervous system of essentially all animals. To elucidate the contribution of specific cell types to both physiological and pathological brain states, it is important to access detailed neuroanatomy data for quantitative analysis and computational modeling. NeuroMorpho.

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Objective: Pregnant people receiving treatment for opioid use disorders (OUD) are at significant risk of return to use during the postpartum period. Recently, practice groups and other national organizations have called for the co-location of addiction medicine and obstetric care to reduce the burden on pregnant and postpartum people with OUD associated with engaging in treatment. This paper examines the effectiveness of co-locating services in retaining pregnant people with OUD in care following childbirth.

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Article Synopsis
  • This text is about a study that will look at how well different strategies work to reduce violence in communities.
  • The study will find out which methods have been carefully tested, which ones work well, and which ones don’t seem to help.
  • The results will be organized into different groups, like people-focused, place-focused, and behavior-focused approaches, and suggestions will be made for how to use this information in real life.
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Polymeric biomaterials are a widely used class of materials due to their versatile properties. However, as with all other types of materials used for biomaterials, polymers also have to interact with blood. When blood comes into contact with any foreign body, it initiates a cascade which leads to platelet activation and blood coagulation.

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In 2023 human populations experienced multiple record-breaking climate events, with widespread impacts on human health and well-being. These events include extreme heat domes, drought, severe storms, flooding, and wildfires. Due to inherent lags in the climate system, we can expect such extremes to continue for multiple decades after reaching net zero carbon emissions.

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An introduction to the themed collection on multicomponent plasmonic hybrid nanoarchitectures with precisely tailored properties for emerging applications, featuring burgeoning research on a variety of multifunctional plasmonic nanoparticles with synergistically reinforced properties.

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Article Synopsis
  • A study compared distal transradial access (dTRA) and forearm transradial access (fTRA) for coronary angiography, focusing on how each affects the healing of the radial artery after the procedure.
  • 64 patients were randomly assigned to either dTRA or fTRA and were monitored using high-resolution vascular ultrasound for changes in forearm radial artery thickness and other outcomes after 90 days.
  • Results showed no significant differences in radial artery healing, hand pain, or function between the two access methods, suggesting both are equally effective, but further research is needed for better understanding.
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Mineral licks are key ecological components of the Amazon rainforest, providing critical dietary functions for herbivorous and frugivorous mammals and birds, which help maintain the structure and function of the forest itself through seed and nutrient dispersal. One of the most frequent visitors of interior forest mineral licks in the Amazon is the red brocket deer (), a large-bodied ruminant frugivore and seed predator. While several hypotheses for the drivers of geophagy exist, including mineral supplementation, toxin adsorption, and habitat selection, robust data on geophagy for the red brocket deer for large numbers of mineral licks is nonexistent.

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This work was devoted to the investigation of the optical properties, structural characterization, and photothermal conversion performance of Ag@CuO nanostructures. The selection of anisotropic silver core, specifically Ag nanocubes, was driven by the possibility to tune LSPR across a broader range of the electromagnetic spectrum. The thickness of the CuO shell was intentionally changed through the variation in the Cu salt to the metal core nanoparticles ratios.

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The Crested-tailed deer mouse, , is one of seven arboreal species within the genus . Species of this genus are monotypic, relatively rare, and occur in low densities. Their geographical distribution is highly fragmented due to being restricted to montane cloud forest in Mesoamerica and they are of conservation concern.

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Regional populations of geographically widespread species may respond to different environmental factors across the species' range, generating divergent effects of climate change on life-history phenology. Using thousands of citizen science observations extracted from iNaturalist and associated with corresponding temperature, precipitation, elevation, and daylength information, we examined the drivers of adult mating and of nymphal phenology, development, and group size for populations of the large milkweed bug, , in different ecoregions. Research-grade iNaturalist images were correctly identified 98.

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The Pliocene offers insights into future climate, with near-modern atmospheric pCO and global mean surface temperature estimated to be 3-4°C above pre-industrial. However, the hydrological response differs between future global warming and early Pliocene climate model simulations. This discrepancy results from the use of reduced meridional and zonal sea surface temperature (SST) gradients, based on foraminiferal Mg/Ca and Alkenone proxy evidence, to force the early Pliocene simulation.

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Background: Most national counter-radicalization strategies identify the media, and particularly the Internet as key sources of risk for radicalization. However, the magnitude of the relationships between different types of media usage and radicalization remains unknown. Additionally, whether Internet-related risk factors do indeed have greater impacts than other forms of media remain another unknown.

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This is the protocol for a Campbell systematic review. The objective is to assess the effects of interrogation approach on confession outcomes for criminal (mock) suspects.

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