Association of polymorphisms with imatinib treatment outcome in Azerbaijani chronic myeloid leukaemia patients.

Background & Objectives: Imatinib mesylate (IM) is a reliable first line treatment for chronic myeloid leukaemia (CML). Nevertheless, despite promising results, a considerable proportion of patients develop resistance to the drug. Cytochrome P450 (CYP) enzymes play a crucial role in IM metabolism.

CYP2B6 SINGLE NUCLEOTIDE POLYMORPHISMS IN AN AZERBAIJANI POPULATION.

Despite being one of the less-characterized human isoforms, cytochrome P450 2B6 is already known for its participation in the metabolism of many drugs and several environmental carcinogens. It has been studied in different populations, but ethnicity is a crucial variable to account for interindividual variability. ; This study aimed to investigate the genotype and allelic frequencies of CYP2B6 c.

Isolation and Sequencing of Chromosome Arm 7RS of Rye, .

Rye () is a climate-resilient cereal grown extensively as grain or forage crop in Northern and Eastern Europe. In addition to being an important crop, it has been used to improve wheat through introgression of genomic regions for improved yield and disease resistance. Understanding the genomic diversity of rye will assist both the improvement of this crop and facilitate the introgression of more valuable traits into wheat.