2,459 results match your criteria: "General hospital of Athens[Affiliation]"

Bronchogenic cysts, first described in 1859, are rare congenital cystic malformations of the respiratory tract, with an incidence of one per 42,000-68,000 hospital admissions in one hospital series. They comprise 10-15% of mediastinal tumors and between 50% and 60% of mediastinal cystic lesions. Its clinical diagnosis is often challenging due to the absence of distinct imaging features.

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Invasive lobular carcinoma (ILC) represents a rare subtype of breast carcinoma, originating from the lobule. Unlike ductal carcinoma, ILC does not express E-cadherin and thus can metastasize to uncommon sites. We aimed to investigate the clinicopathological characteristics of the rare subgroup of ILC patients with gastrointestinal (GI) metastases.

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The Use of the Robotic Arm-Assisted System (MAKO) for Hip Revision Surgery.

Arch Bone Jt Surg

January 2024

Department of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, Athens, Greece.

The robotic arm-assisted system (MAKO) has pioneered a transformative approach to hip joint restoration, excelling in reinstating innate hip joint anatomy and biomechanics. This case represents the initial application of the system in revision surgery following a cut-out complication. A 69-year-old female, previously independent and mobile, presented with left hip pain.

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Objectives: To assess the perceptions of patients with rheumatic diseases about the doctor-patient relationship and the impact on their treatment and their quality of life.

Methods: A quantitative study collecting data from patients with rheumatic diseases using the following tools: (a) the Doctor-Patient Relationship Assessment Questionnaire-16 (DoPRAQ-16), assessed the quality of doctor-patient relationship, (b) the Short Form 36 (SF-36) assessed the quality of life of patients, and (c) the Health Assessment Questionnaire (HAQ), assessed the functional ability of patients. From the statistical analysis, it appears that there is no linear correlation between the DoPRAQ-16 scales and the dimensions of the SF-36 Health Survey, except for the scale of negative emotions and the dimension of Physical Functioning.

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Background: COVID-19 continues to pose a threat to immunocompromised individuals, even with vaccination. The monoclonal antibodies (mAbs) tixagevimab/cilgavimab (TXG/CIL) provide targeted prophylaxis against SARS-CoV-2 with the benefit of a prolonged half-life. Although approved for COVID-19 prevention, there is limited data on their effectiveness among heavily immunocompromised populations.

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Breast cancer (BC) is the most prominent tumor type among women, accounting for 32% of newly diagnosed cancer cases. BC risk factors include inherited germline pathogenic gene variants and family history of disease. However, the etiology of the disease remains occult in most cases.

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To assess the effect of hysteroscopic polypectomy on the in vitro fertilization (IVF) results in infertile women with at least one prior negative IVF outcome. This retrospective cohort study included women who had attended the "2nd Department of Obstetrics and Gynecology of the National and Kapodistrian University of Athens" and "Iaso" Maternity Hospital from October 2019 to January 2023 for infertility treatment. The medical records of 345 women aged 18-45 years old without abnormal findings in hysterosalpingography (HSG) and with at least one previous failed IVF procedure were analyzed.

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Tricuspid regurgitation (TR) is an intricate disorder that has a negative outlook, while surgical treatment is linked to increased mortality. Primary TR occurs due to a structural defect in the tricuspid valve (TV), while secondary TR is a more prevalent condition often associated with pulmonary hypertension, heart failure, and atrial fibrillation. The use of specific surgical procedures to improve TR is limited in everyday clinical practice due to the heightened surgical risk and delayed patient presentation.

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Background: Despite its high prevalence and impact on health, metabolic dysfunction-associated steatotic liver disease (MASLD) is inadequately addressed in European primary care (PC), with a large proportion of cases going undiagnosed or diagnosed too late. A multi-country European research consortium led a project to design and evaluate a patient-centered, integrated model for MASLD screening, diagnosis, and linkage to specialty care for European PC settings. Based on the lessons from this project, the latest research evidence, and existing guidelines for the management of MASLD, we sought to develop a set of practice recommendations for screening, referral, and management of MASLD in PC.

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The Impact of Cardiopulmonary Rehabilitation on Ventriculoarterial Coupling in Post-Coronavirus Disease-2019 Patients.

J Cardiopulm Rehabil Prev

September 2024

Author Affiliations: Department of Cardiology, "Sotiria" Chest Disease Hospital, National and Kapodistrian University of Athens, Medical School, Athens, Greece (Drs Gounaridi, Souvaliotis, Lampsas, Anastasiou, Goliopoulou, Tzima, Katsarou, Vavouranakis, Siasos, and Oikonomou); Rehabilitation Unit-1st Respiratory Medicine Department, "Sotiria" Chest Disease Hospital, National and Kapodistrian University of Athens, Greece (Dr Vontetsianos, Chynkiamis, Bakakos, and Koulouris); 1st Department of Cardiology, "Hippokration" General Hospital of Athens, National and Kapodistrian University of Athens, Medical School, Athens, Greece (Dr Theofilis).

Article Synopsis
  • - The study investigates how a 3-month cardiopulmonary rehabilitation program affects heart health and blood vessel stiffness in people recovering from COVID-19, comparing them to a non-COVID-19 group.
  • - Results show significant improvements in arterial stiffness (PWV) and left ventricular function in the COVID-19 group who participated in rehabilitation, while these measures remained poor in those who didn't.
  • - The findings suggest that rehabilitation effectively enhances recovery in heart-related metrics and overall physical fitness in post-COVID-19 patients, emphasizing the importance of such programs after the illness.
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Certain high-energy blunt forces may produce unstable cervical fractures with or without dislocation. In rare cases where the superior facets are dislocated, however showing a significant increase within the last decade, these types of injuries may include vertebral artery entrapment at the involvement level leading to artery dissection or occlusion. This phenomenon is usually seen at the C4-C5 and C5-C6 levels of injury.

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is a difficult-to-treat, multidrug-resistant human pathogen. Relebactam has been shown to inhibit β-lactamase (BLA) and increase the activity of imipenem and amoxicillin. We present two cases of lung infection due to , one caused by subsp and the other by subsp.

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An older woman developed dyspnea after instrumented lumbar spinal fusion surgery. During clinical work-up, a chest radiography revealed a U-shaped object within the cardiac silhouette. Further imaging confirmed that the object was entrapped in the tricuspid subvalvular apparatus.

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Patient-reported knee-related rating scores and scales are widely used in reporting the clinical outcomes of anterior cruciate ligament (ACL) surgery. Understanding the psychometric properties of such measures is vital to recognizing the limitations that such measures may confer. The aim of this study was to review the available evidence as to the psychometric properties of patient-reported outcome measures (PROMs) used in ACL surgery.

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Introduction: Despite the technological advancements in catheter ablation strategies, the recurrence of atrial fibrillation (AF) post-ablation remains a concern that requires further investigation. Glucagon-like peptide 1 (GLP-1) receptor agonists have shown a significant effect on weight reduction, which in turn is associated with freedom from AF recurrence in both patients who are obese and not obese undergoing ablation. Therefore, we aimed to summarize the available evidence on the efficacy of GLP-1 receptor agonists in maintaining sinus rhythm post-ablation.

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The impact of sex on the prognosis of patients with esophageal cancer remains unclear. Evidence supports that sex- based disparities in esophageal cancer survival could be attributed to sex- specific risk exposures, such as age at diagnosis, race, socioeconomic status, smoking, drinking, and histological type. The aim of our study is to investigate the role of sex disparities in survival of patients who underwent surgery for esophageal cancer.

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Article Synopsis
  • Scientists wanted to see how different storage solutions affect blood platelets that are treated to kill germs.
  • They tested platelets stored in plasma and Platelet Additive Solutions (PAS) from the same donors and checked their health on days 1, 3, and 5.
  • Results showed that PAS kept the platelets healthier than plasma, but both types had less ability to stop bleeding over time.
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Periprosthetic fractures involving total knee arthroplasty (TKA) components, particularly involving the patella, can present a significant challenge regarding orthopedic surgery. This technical note outlines an approach for the reconstruction of complicated periprosthetic transpatellar fractures, with poor bone stock, utilizing autogenous iliac graft. This kind of procedure requires careful preoperative evaluation of imaging, precise intraoperative planning, and strict postoperative management to achieve adequate postoperative results.

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Background: Thyroid hormone (TH) appears to have a reparative action on the postinfarcted myocardium. This novel action was recently tested in a pilot, randomized, double-blind, placebo-controlled trial (ThyRepair). The present study performed a analysis of data from the ThyRepair study to provide further insights into the novel actions of TH on the human postischemic myocardium.

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Article Synopsis
  • Severe traumatic brain injury (sTBI) is a significant health issue, leading to around 300,000 ICU admissions each year and having a 30% mortality rate, which highlights the need for improved management despite low treatment evidence.
  • The occurrence of pulmonary embolism (PE) in sTBI patients complicates treatment due to the risks associated with anticoagulating an already injured brain.
  • A literature review was conducted, analyzing recent studies on sTBI and PE, resulting in 38 relevant papers that discuss the prevalence, risk factors, diagnostic challenges, prophylaxis timing, and treatment options for PE in these patients.
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EJPC @ a glance: focus on congenital heart diseases and heart failure.

Eur J Prev Cardiol

August 2024

Department of Cardiology, Dupuytren University Hospital, 2, Martin Luther King avenue, 87025, 2, Rue Marcland Limoges, France.

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Background: Several anatomical variations of the ilioinguinal nerve branches have been recorded in older studies. Knowledge of these variations is useful for the improvement of peripheral nerve blocks and avoidance of iatrogenic nerve injuries during abdominal surgeries. The purpose of this study is to perform a systematic review of the literature about the anatomical topography and variations of the ilioinguinal nerve.

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Relapses and serious adverse events during rituximab maintenance therapy in ANCA-associated vasculitis: a multicentre retrospective study.

Rheumatology (Oxford)

August 2024

Joint Rheumatology Program, Clinical Immunology-Rheumatology Unit, 2nd Department of Medicine and Laboratory, National and Kapodistrian University of Athens, School of Medicine, General Hospital of Athens "Hippokration", Athens, Greece.

Objectives: There are limited real-life data regarding the efficacy and safety of rituximab (RTX) as a remission-maintenance agent in microscopic-polyangiitis (ΜPA) and granulomatosis-with-polyangiitis (GPA). We aimed to estimate the incidence and risk factors for relapses, as well serious-adverse-events (SAEs) in MPA/GPA patients during RTX-maintenance.

Methods: Retrospective cohort of newly-diagnosed/relapsing GPA/MPA patients who received RTX-maintenance (≥1 RTX-cycle, ≥6 months follow-up) following complete-remission (Birmingham-Vasculitis-Activity-Score-version-3 = 0 plus prednisolone ≤7.

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Article Synopsis
  • Patients with inflammatory bowel disease (IBD) are at a higher risk for hepatitis B virus (HBV) and should ideally be vaccinated; this study evaluated the effectiveness of HBV vaccination among these patients and factors influencing their immune response.
  • A total of 409 IBD patients were studied, with 66.7% responding to the initial vaccination; those with lower body mass index had better immune responses, while certain disease types and treatments negatively impacted response rates.
  • Among nonresponders receiving revaccination, 58.3% achieved protective antibody levels, indicating that enhanced revaccination could benefit about half of these patients despite overall lower responsiveness compared to the general population.
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