6 results match your criteria: "General University Hospital Valencia[Affiliation]"
Decoding the meaning of medical guidelines and their medicolegal implications.
Eur J Anaesthesiol
February 2024
From the University Hospital Würzburg, Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, Würzburg, Germany (PK, PM), Department of Paediatric and Obstetric Anaesthesia, Juliane Marie Centre, Rigshospitalet & Department of Clinical Medicine, Copenhagen University, Denmark (AA), Department of Anesthesiology, Division of Vital Functions, Universitair Medisch Centrum Utrecht, Utrecht, the Netherlands (WB), Ulsenheimer Friederich Rechtsanwälte PartGmbB, Munich, Germany (SW), General University Hospital Valencia, Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine (CR), and Research Methods Department, Universidad Europea de Valencia, Valencia, Spain (CR).
Medical practice guidelines (MPGs) are important in medicine to ensure well tolerated and effective healthcare. They provide evidence-based recommendations for healthcare professionals in daily clinical settings. MPGs help patients and practitioners make informed decisions, ensure quality of care, allocate healthcare resources effectively and reduce legal liability.
View Article and Find Full Text PDFAntibiotics for the treatment of COVID-19.
Emergencias
October 2023
Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, University Hospital Wuerzburg, Wuerzburg, Alemania.
Antibiotics for the treatment of COVID-19.
Cochrane Database Syst Rev
October 2021
Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, University Hospital Wuerzburg, Wuerzburg, Germany.
Background: The effect of antibiotics with potential antiviral and anti-inflammatory properties are being investigated in clinical trials as treatment for COVID-19. The use of antibiotics follows the intention-to-treat the viral disease and not primarily to treat bacterial co-infections of individuals with COVID-19. A thorough understanding of the current evidence regarding effectiveness and safety of antibiotics as anti-viral treatments for COVID-19 based on randomised controlled trials (RCTs) is required.
View Article and Find Full Text PDFPrognostic Impact of KRAS G12C Mutation in Patients With NSCLC: Results From the European Thoracic Oncology Platform Lungscape Project.
J Thorac Oncol
June 2021
European Thoracic Oncology Platform, Bern, Switzerland.
Introduction: KRAS mutations, the most frequent gain-of-function alterations in NSCLC, are currently emerging as potential predictive therapeutic targets. The role of KRAS-G12C (Kr_G12C) is of special interest after the recent discovery and preclinical analyses of two different Kr_G12C covalent inhibitors (AMG-510, MRTX849).
Methods: KRAS mutations were evaluated in formalin-fixed, paraffin-embedded tissue sections by a microfluidic-based multiplex polymerase chain reaction platform as a component of the previously published European Thoracic Oncology Platform Lungscape 003 Multiplex Mutation study, of clinically annotated, resected, stage I to III NSCLC.
Objective: To analyze the effectiveness and tolerability of perampanel across different seizure types in routine clinical care of patients with idiopathic generalized epilepsy (IGE).
Methods: This multicenter, retrospective, 1-year observational study collected data from patient records at 21 specialist epilepsy units in Spain. All patients who were aged ≥12 years, prescribed perampanel before December 2016, and had a confirmed diagnosis of IGE were included.
Influence of and genetic variability on personality dimensions in anorexia and bulimia nervosa.
Brain Behav
September 2017
Article Synopsis
- The study investigates the role of obesity-related genes in influencing feeding behavior and their potential link to eating disorders (ED) and psychological traits among participants.
- Researchers screened 425 individuals, including eating disorder patients and obese subjects, using genetic testing and psychometric evaluations to gather data on gene variants and mental health scores.
- Results showed a specific gene variant associated with an increased risk of bulimia nervosa and a notable difference in genetic profiles between controls and eating disorder patients, suggesting genetic factors may play a role in the risk of developing EDs.