6 results match your criteria: "General Hospital of Goumenissa[Affiliation]"
Epigenetic editing and tumor-dependent immunosuppressive signaling in head and neck malignancies.
Oncol Lett
June 2022
Pulmonary Department, General Hospital of Thessaloniki 'G. Papanikolaou', Aristotle University of Thessaloniki, Thessaloniki GR-57010, Greece.
Head and neck cancer (HNC) comprises a heterogeneous variety of malignant tumors, characterized by a relatively high tumor mutation burden. Previous data have revealed that immune system dysfunction appears to serve a key role in the development and progression of HNC and established immunosuppression is vital for evading the host immune response. Despite progress in chemotherapy and radiotherapy, the survival rate of patients with HNC is still low.
View Article and Find Full Text PDFAssociation between lipoprotein(a) concentrations and atherosclerotic cardiovascular disease risk in patients with familial hypercholesterolemia: an analysis from the HELLAS-FH.
Endocrine
May 2022
Department of Endocrinology, Police Medical Centre of Thessaloniki, Thessaloniki, Greece.
Article Synopsis
- The study investigates the link between lipoprotein(a) [Lp(a)] levels and the prevalence of atherosclerotic cardiovascular disease (ASCVD) in adults with familial hypercholesterolemia (FH).
- In a sample of 541 patients, those with higher Lp(a) concentrations showed a notable increase in ASCVD prevalence, with rates rising from 9.4% in the lowest tertile to 20.6% in the highest.
- The findings suggest that elevated Lp(a) levels are an important risk factor for ASCVD in individuals with FH, emphasizing the need for monitoring and addressing Lp(a) in this population.
Prophylactic antibiotic treatment in severe acute ischemic stroke: the Antimicrobial chemopRrophylaxis for Ischemic STrokE In MaceDonIa-Thrace Study (ARISTEIDIS).
Intern Emerg Med
October 2016
First Propedeutic Department of Internal Medicine, AHEPA Hospital, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Infections represent a leading cause of mortality in patients with acute ischemic stroke, but it is unclear whether prophylactic antibiotic treatment improves the outcome. We aimed to evaluate the effects of this treatment on infection incidence and short-term mortality. This was a pragmatic, prospective multicenter real-world analysis of previously independent consecutive patients with acute ischemic stroke who were >18 years, and who had at admission National Institutes of Health Stroke Scale (NIHSS) >11.
View Article and Find Full Text PDFThe Role of Mean Platelet Volume in Chronic Obstructive Pulmonary Disease Exacerbation.
Respir Care
January 2016
Department of Internal Medicine, General Hospital of Goumenissa, Goumenissa, Greece.
Background: Studies have supported the correlation between mean platelet volume and COPD. However, there are limited data on the relationship between COPD exacerbation and mean platelet volume. We aimed to evaluate the mean platelet volume trend in patients with COPD exacerbation.
View Article and Find Full Text PDFA Case of Fenofibrate-Induced Immune Thrombocytopenia: First Report.
P R Health Sci J
September 2015
General Hospital of Hippokratio, Thessaloniki, Greece.
Fenofibrate is widely prescribed as a hypolipidemic drug and is well tolerated by most patients. We present the case of a 40-year-old woman who developed severe immune thrombocytopenia while on fenofibrate treatment. Clinical features included spontaneous bruising on the feet and hands, a purpuric rash, and menorrhagia.
View Article and Find Full Text PDFPurple Urine Bag Syndrome: a case report of an alarming phenomenon.
Hippokratia
January 2014
Department of Internal Medicine, General Hospital of Goumenissa, Kilkis, Greece.
Background: Purple urine bag syndrome is an uncommon phenomenon where the plastic urinary catheter bag and tubing turn purple. It occurs in some elderly constipated chronic urinary catheterization patients. The phenomenon is attributed to the presence of metabolites of tryptophan in the presence of urinary tract infection.
View Article and Find Full Text PDF