685 results match your criteria: "General Hospital of Athens "KAT"[Affiliation]"

Introduction: Isolated ruptures of the vastus lateralis (VL) tendon are exceptionally rare, with few reported cases in the orthopedic literature. This case report sheds light on non-surgical management for partial VL tendon ruptures, providing insight into an alternative treatment pathway that avoids surgical intervention.

Case Report: A 27-year-old Caucasian male experienced a partial, isolated rupture of the VL tendon after a minor fall.

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Patient-reported knee-related rating scores and scales are widely used in reporting the clinical outcomes of anterior cruciate ligament (ACL) surgery. Understanding the psychometric properties of such measures is vital to recognizing the limitations that such measures may confer. The aim of this study was to review the available evidence as to the psychometric properties of patient-reported outcome measures (PROMs) used in ACL surgery.

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Periprosthetic fractures involving total knee arthroplasty (TKA) components, particularly involving the patella, can present a significant challenge regarding orthopedic surgery. This technical note outlines an approach for the reconstruction of complicated periprosthetic transpatellar fractures, with poor bone stock, utilizing autogenous iliac graft. This kind of procedure requires careful preoperative evaluation of imaging, precise intraoperative planning, and strict postoperative management to achieve adequate postoperative results.

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Exploration of surgical precision in robotic procedures is extensive, yet lacks a unified framework for comparability. This study examines tissue handling precision by comparing the per-minute blood loss rate between robotic and open partial nephrectomy. A literature search from August 2022 to June 2024 identified 43 relevant studies providing data on estimated blood loss and procedure duration.

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Background: Several anatomical variations of the ilioinguinal nerve branches have been recorded in older studies. Knowledge of these variations is useful for the improvement of peripheral nerve blocks and avoidance of iatrogenic nerve injuries during abdominal surgeries. The purpose of this study is to perform a systematic review of the literature about the anatomical topography and variations of the ilioinguinal nerve.

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Nonalcoholic fatty liver disease (NAFLD) poses an emerging threat topublic health. Nonalcoholic steatohepatitis (NASH) is reported to be the most rapidly rising cause of hepatocellular carcinoma in the western world. Recently, a new term has been proposed: metabolic dysfunction-associated steatotic liver disease (MASLD).

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Introduction: Lipomas are the most common benign mesenchymal tumors found on the head, neck, shoulder, and back, but they are rarely encountered in the fingers, constituting <1% of such tumors.

Case Report: This case report presents an exceptional location of a giant lipoma on the proximal phalanx of a 60-year-old Caucasian male's rightindex finger, alongside a literature review that identified 20 similar cases. The patient, with no significant health issues, reported that the growthhad been asymptomatic for 2 years before seeking consultation due to aesthetic concerns and impaired finger extension.

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Article Synopsis
  • Ankylosing spondylitis (AS) is a serious condition that causes chronic inflammation and damage mainly to the spine, negatively affecting patients' quality of life.
  • Recent advances in treatment, particularly with TNF-α inhibitors, have significantly improved symptom relief and patient outcomes.
  • A review of 35 studies shows these inhibitors effectively reduce inflammation, prevent structural damage, and enhance well-being in AS patients, proving to be a key part of their treatment with a good safety record.
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Progression of multiple vertebral fractures after denosumab discontinuation under treatment with romosozumab. A case-report.

Joint Bone Spine

September 2024

Laboratory for Research of the Musculoskeletal System "Th. Garofalidis", Medical School, National and Kapodistrian University of Athens, KAT General Hospital, Kifissia, Athens, Greece. Electronic address:

Introduction: Denosumab (Dmab) is widely used for the treatment of post-menopausal osteoporosis. Its discontinuation is sometimes accompanied by multiple vertebral fractures. Romosozumab (Rmab) has not been tested for its ability to prevent the rebound phenomenon.

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Spinal cord compression is a formidable complication of advanced cancer, and clinicians of copious specialities often have to encounter significant complex challenges in terms of diagnosis, management, and prognosis. Metastatic lesions from cancer are a common cause of spinal cord compression, affecting a substantial portion of oncology patients, and only in the US has the percentage risen to 10%. Acute metastasis-correlated spinal cord compression poses a considerable clinical challenge, necessitating timely diagnosis and intervention to prevent neurological deficits.

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Unraveling the Link of Altered TGFβ Signaling with Scoliotic Vertebral Malformations in Osteogenesis Imperfecta: A Comprehensive Review.

J Clin Med

June 2024

Third Department of Orthopaedic Surgery, School of Medicine, National and Kapodistrian University of Athens, "KAT" General Hospital, Nikis 2, 14561 Athens, Greece.

Article Synopsis
  • * Scoliosis in OI patients is characterized by various vertebral deformities like wedged vertebrae and abnormalities at the craniocervical junction, and its progression is linked to reduced Bone Mineral Density and multiple contributing factors such as mechanical strain and bone metabolism anomalies.
  • * Investigating the molecular mechanisms, particularly the role of Transforming Growth Factor-β (TGFβ) signaling, offers potential insights for new therapeutic strategies targeting the bone and muscle challenges faced by OI patients.
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Background: Insulin exerts a crucial impact on glucose control, cellular growing, function, and metabolism. It is partially modulated by nutrients, especially as a response to the intake of foods, including carbohydrates. Moreover, insulin can exert an anorexigenic effect when inserted into the hypothalamus of the brain, in which a complex network of an appetite/hunger control system occurs.

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Introduction: Periprosthetic joint infections (PJIs) are a devastating complication of total hip (THA) and knee (TKA) arthroplasty. The use of novel techniques like multiplex cytokine analysis could contribute immensely to the identification of potential novel biomarkers.

Patients And Methods: This is a single-centre study of patients that were treated with revision TKA, THA or hemiarthroplasty.

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Article Synopsis
  • * These drugs can affect various tissues in the body, leading to lower glucocorticoid levels and altering androgen regulation, which may result in metabolic issues like liver disease and diabetes.
  • * The study aims to review existing research on how these medications influence metabolic health and to explore the mechanisms behind these potential side effects, highlighting the need for further clinical trials.
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Objective Real-life management of patients with hypertension and chronic kidney disease (CKD) among European Society of Hypertension Excellence Centres (ESH-ECs) is unclear : we aimed to investigate it. Methods A survey was conducted in 2023. The questionnaire contained 64 questions asking ESH-ECs representatives to estimate how patients with CKD are managed.

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Background Deep brain stimulation (DBS) is a well-recognised treatment for advanced Parkinson's disease (PD) patients. Structural brain alterations of the white matter can correlate with disease progression and act as a biomarker for DBS therapy outcomes. This study aims to develop a machine learning-driven predictive model for DBS patient selection using whole-brain white matter radiomics and common clinical variables.

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Fractures of the coronoid process typically occur as part of more complex injury patterns, such as terrible triads, trans-olecranon fracture-dislocations, posteromedial rotatory injuries or Monteggia-like lesions. Each pattern is associated with a specific type of coronoid fracture with regard to shape and size and specific soft-tissue lesions. O' Driscoll classification incorporates those associations identifying three major types of fractures: tip, anteromedial facet, and basal fractures.

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Prevalence, awareness, and control of hypertension in Greece before and after the COVID-19 pandemic: May Measurement Month survey 2019-2022.

Hellenic J Cardiol

May 2024

Hypertension Center STRIDE-7, National and Kapodistrian University of Athens, Third Department of Medicine, Sotiria Hospital, 152 Mesogion Avenue, Athens 11527, Greece. Electronic address:

Article Synopsis
  • The study aimed to assess the impact of the COVID-19 pandemic on hypertension awareness and treatment in Greece, analyzing data collected in 2019 and 2022 during the May Measurement Month (MMM) initiative.
  • Data from over 12,000 adults revealed consistent hypertension prevalence rates (around 41-43%) before and after the pandemic, but an increase in undiagnosed cases was observed, rising from 21.3% to 27.5%.
  • The findings suggest that while the overall prevalence of hypertension remained stable, there is a pressing need for improved national strategies to detect and manage hypertension effectively in Greece, especially post-pandemic.
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Article Synopsis
  • The study aimed to analyze the characteristics and risk factors of medication-related osteonecrosis of the jaw (MRONJ) across various European Oral and Maxillofacial Surgery centers, to enhance understanding of its epidemiology and treatment trends.
  • Data was collected from 537 patients, revealing significant links between metastatic bone disease, advanced MRONJ stages, male gender, and higher recurrence rates of MRONJ.
  • Findings suggest that patients with osteoporosis experienced a longer duration of antiresorptive medication before MRONJ onset, while those with metastatic bone cancer, especially prostate cancer or multiple myeloma, had a shorter duration, emphasizing the importance of surgical intervention in managing MRONJ.
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Surgical site infections (SSIs) following open reduction and internal fixation (ORIF) of ankle fractures can lead to significant disability. This case report emphasizes a unique instance of SSI caused by , following ORIF of a trimalleolar ankle fracture in a 55-year-old female patient. To our knowledge, this is the first reported case of infection after ORIF in the literature.

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Postoperative air leak (PAL) is a frequent and potentially serious complication following thoracic surgery, characterized by the persistent escape of air from the lung into the pleural space. It is associated with extended hospitalizations, increased morbidity, and elevated healthcare costs. Understanding the mechanisms, risk factors, and effective management strategies for PAL is crucial in improving surgical outcomes.

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Background: The global population, especially in the Western world, is constantly aging and the need for total hip arthroplasties has rocketed, hence there has been a notable increase in revision total hip arthroplasty cases. As time has passed, a considerable developments in science and medicine have been attained which have also resulted in the evolution of both surgical techniques and implants. Continuous improvements have allowed large bore bearings to be utilized which provide an increased range of motion, with ameliorated stability and a very low rate of wear.

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Purpose: The purpose of this study was to (a) record and evaluate the epidemiological data relevant to the fractures of the atrophic mandible in the Greek population (b) present our experience in the management of these difficult injuries and (c) compare our results to the outcomes of other similar studies and discuss the postoperative complications.

Methods: A prospective analysis of all the edentulous patients with fractures of the atrophic mandible treated at the Oral and Maxillofacial Surgery Department of K.A.

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Background: Perilunate dislocations and perilunate fracture dislocations (PLD/PLFDs) are rare injuries of the wrist, with surgical management leading to acceptable functional results.

Purpose: The purpose of this study was to assess the functional outcomes of the patients of our department who were treated with surgical management of PLDs/PLFDs through dorsal approach, as well as to report any complications on their follow-up.

Patients And Methods: In this retrospective study, 52 patients with PLD/PLFD, fulfilling the inclusion and exclusion criteria of the study, underwent surgical management of their injury.

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Objective: To present the characteristics of patients with potential difficult-to-treat (D2T) PsA.

Methods: We used data from the Greek multicentre registry of PsA patients. D2T PsA was defined as follows: patients with at least 6 months' disease duration, who have failed to at least one conventional synthetic DMARD and at least two biologic DMARDs/targeted synthetic DMARDs with a different mechanism of action and have either at least moderate disease activity (MODA) defined as DAPSA (Disease Activity index in PSoriatic Arthritis) >14, and/or are not at minimal disease activity (MDA).

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