3 results match your criteria: "General Hospital Karlsruhe.[Affiliation]"

No long-term impairment of cerebral autoregulation after preeclampsia.

Pregnancy Hypertens

July 2018

Department of Neurology, Medical Center, University of Freiburg, Germany; Department of Neurology and Clinical Neurophysiology, Medical Center Esslingen, Academic Teaching Hospital of the University of Tübingen, Germany.

Introduction: Preeclampsia is a pregnancy-related hypertensive disorder with strongly impaired cerebral autoregulation in the acute stage. A history of preeclampsia is an independent cardiovascular and cerebrovascular risk factor. It is unclear whether impaired cerebral autoregulation persists after preeclampsia and thus contributes to the known increased cerebrovascular morbidity.

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Therapy of cutaneous T cell lymphoma (CTCL) is complicated by a distinct resistance of the malignant T cells towards apoptosis that can be caused by NRAS mutations in late-stage patients. These mutations correlate with decreased overall survival, but sensitize the respective CTCL cells towards MEK-inhibition-induced apoptosis which represents a promising novel therapeutic target in CTCL. Here, we show that the multi-kinase inhibitor Sorafenib induces apoptosis in NRAS-mutated CTCL cells.

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Reconstruction of the lower lip: rationale to preserve the aesthetic units of the face.

Plast Reconstr Surg

October 2007

Regensburg, Bonn, Karlsruhe, and Kiel, Germany From the Departments of Oral and Maxillofacial Surgery, University of Regensburg and University of Bonn, Department of Oral and Maxillofacial Surgery, Institute of Medical Informatics and Statistics, University Schleswig-Holstein, Campus Kiel, and Department of Oral and Maxillofacial Surgery, General Hospital Karlsruhe.

Background: The boundaries of the aesthetic units of the face are often crossed after lower lip cancer surgery. The aim of this study was to compare the aesthetic and functional outcome after use of different operative techniques based on the concept of the aesthetic units of the face.

Materials: Sixty-three patients were evaluated after lower lip reconstruction.

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