1,898 results match your criteria: "General Hospital "PAPAGEORGIOU"[Affiliation]"

Type IV collagen-related nephropathy as a diagnosis in nephrotic syndrome.

Pediatr Nephrol

March 2025

First Department of Pediatrics, Aristotle University of Thessaloniki, Hippokration General Hospital of Thessaloniki, 49th Konstantinoupoleos Street, Thessaloniki, Greece.

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Adenotonsillectomy Versus Watchful Waiting for Children with Obstructive Sleep Apnea Syndrome: A Systematic Review with Meta-Analysis.

Indian J Otolaryngol Head Neck Surg

October 2024

1st Department of Otorhinolaryngology-Head and Neck Surgery, AHEPA University General Hospital, Aristotle University of Thessaloniki, Kiriakidi 1, Thessaloniki, 546 21 Greece.

Article Synopsis
  • This study investigates the effectiveness of adenotonsillectomy (ATE) versus watchful waiting in children with Obstructive Sleep Apnea Syndrome (OSAS), examining their clinical outcomes through a meta-analysis of various trials.
  • The results show ATE leads to significant improvements in the apnea-hypopnea index (AHI) and quality of life (measured by OSA-18 scores), but no noticeable difference was found in oxygen saturation levels (SpO2) between the two treatment options.
  • Subgroup analysis also indicated ATE is particularly beneficial for mild OSAS cases, showcasing significant improvements compared to watchful waiting.
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Introduction: Current literature is inconclusive as to whether transversus abdominis (TrA) training can provide an additional benefit to pelvic floor muscle (PFM) training in female stress urinary incontinence (SUI). We designed a study to investigate the effect of PFM and TrA training on incontinence parameters.

Material And Methods: 60 females with SUI were randomised to PFM training alone or PFM plus TrA training.

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Antimicrobial resistance poses a major threat to human health worldwide and the implementation of antimicrobial stewardship programs (ASPs), including antimicrobial de-escalation (ADE), is a multifaceted tool for minimizing unnecessary or inappropriate antibiotic exposure. This was a prospective observational study of 142 non-Intensive Care Unit (ICU) patients with microbiologically documented infection who were initially administered empirical antimicrobial therapy and admitted to the medical wards of 6 tertiary-care hospitals in Greece from January 2017 to December 2018. Patients were divided into two groups, the ADE and non-ADE group, based on whether ADE was applied or not, respectively.

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Background: Attendance to neonatal follow-up programs presents a significant factor associated with positive long-term outcomes of high-risk infants. Strategies to maximize participation benefit not only future interventions' effectiveness but also healthcare systems and society. While a number of studies have focused on attrition or loss to follow-up, no studies have focused on the contributive risk factors to abstaining from neonatal follow-up programs specifically during the COVID-19 pandemic.

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Effect of adequacy of empirical antibiotic therapy for hospital-acquired bloodstream infections on intensive care unit patient prognosis: a causal inference approach using data from the Eurobact2 study.

Clin Microbiol Infect

December 2024

OUTCOMEREA Research Group, Drancy, France; Institut National de la Santé et de la Recherche Medicale, Infection Antimicrobial Modelisation Evolution, U1137, Team Decision Science in Infectious Diseases, Paris, France; Assistance Publique Hôpitaux de Paris, Bichat hospital, Medical and infectious diseases ICU, F75018, Paris France. Electronic address:

Article Synopsis
  • Hospital-acquired bloodstream infections (HA-BSI) in ICU patients can be life-threatening, and this study aimed to see how early adequate antibiotic treatment affects 28-day mortality rates for patients who survive at least one day after infection onset.
  • Using data from a multicenter study with 2,418 patients, researchers found that those who received adequate treatment within 24 hours had a lower 28-day mortality rate (32.8%) compared to those who were inadequately treated (40%).
  • The study concluded that inadequate antibiotic therapy within 24 hours contributes significantly to 28-day mortality, indicating that quicker treatment could greatly improve patient outcomes in cases of HA-BSI.
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Background: Mid-Vastus and Medial Parapatellar techniques are used for total knee arthroplasty. Their short-term effects within the first month after surgery are yet unexplored. The purpose of this study was to compare Mid-Vastus and Medial Parapatellar effects on knee strength and balance control, at 5 days, 2 weeks and one month after surgery.

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Epidermal Tumors Arising on Donor Sites From Autologous Skin Grafts: A Systematic Review.

Cutis

August 2024

Dr. Chaitidis is from the Department of Dermatology and Venereology, 424 General Military Training Hospital, Thessaloniki, Greece. Dr. Papadopoulou is from the 3rd Department of Pediatrics, Hippokration General Hospital, Aristotle University of Thessaloniki. Dr. Paraschou is from the 2nd Department of Pulmonology, University General Hospital Attikon, National and Kapodistrian University of Athens, Haidari, Greece, and Hellenic Police Medical Center, Thessaloniki. Dr. Panagiotidis is from the 1st Department of Surgery, Papageorgiou General Hospital, Thessaloniki.

Common complications of skin grafting used to cover cutaneous defects include bleeding, infection, pain, and graft failure. Epidermal tumor development on graft donor sites in the postoperative period has been reported. We performed a systematic search of the literature for cases of epidermal tumors arising on skin graft donor sites in patients undergoing autologous skin graft surgery.

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Effectiveness and safety of methotrexate in the treatment of mycosis fungoides: Real-world data from a multicentre study.

J Eur Acad Dermatol Venereol

September 2024

2nd Department of Dermatology, "Attikon" General Hospital, National & Kapodistrian University of Athens, Medical School, Athens, Greece.

Article Synopsis
  • - The study analyzed the effectiveness and safety of methotrexate (MTX) in treating mycosis fungoides (MF) across different stages, involving 211 patients from five Greek centers, with a median age of 68.3 years.
  • - Results showed an overall response rate of 55.5%, with better outcomes in patients receiving MTX as a first-line treatment and those with erythrodermic disease compared to tumor stage disease.
  • - The study concludes that MTX is a viable first-line treatment option for MF, demonstrating varying progression-free survival rates depending on the disease stage and acceptable safety profiles.
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Inflammatory bowel disease (IBD) is an inflammatory clinical entity with many extraintestinal symptoms, including urinary tract manifestations. However, the bilateral ureteral obstruction is extremely rare. We report a case of bilateral ureteral obstruction in a 12-year-old male patient with ulcerative colitis (UC).

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The impact of the COVID-19 Pandemic on hypertension phenotypes (ESH ABPM COVID-19 study).

Eur J Intern Med

January 2025

Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Clinical Pharmacology and Toxicology, Berlin, Germany.

Article Synopsis
  • * It compared two groups of patients with treated hypertension: one group monitored during the pandemic and another monitored before it, looking at changes in hypertension phenotypes like sustained uncontrolled hypertension (SUCH) and sustained controlled hypertension (SCH).
  • * Results showed no significant changes in the pandemic group’s hypertension phenotypes, while the pre-pandemic group saw an increase in SCH and a decrease in SUCH, suggesting the pandemic negatively impacted blood pressure management.
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[Long-term oncological outcomes after radical prostatectomy in a non-university teaching hospital].

Aktuelle Urol

September 2024

Klinik und Poliklinik für Urologie und Kinderurologie, Klinikum Fulda gAG, Fulda, Germany.

Background: The evaluation of oncological outcomes after radical prostatectomy (RP) is a major component of quality control in prostate cancer (PCa) centres.

Objectives: To evaluate the oncological outcomes after RP in a non-university teaching hospital and compare them with other high-volume PCa centres.

Material Und Methods: This study included 1,161 patients after RP who were divided into two risk groups.

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Article Synopsis
  • The study investigated how the COVID-19 pandemic affected blood pressure control in patients with hypertension using ambulatory blood pressure monitoring (ABPM).
  • Data were compared between two groups: patients measured before the pandemic and those measured during it, with a total of 704 pandemic patients and 916 prepandemic patients included in the analysis.
  • Results showed that during the pandemic, patients had higher blood pressure readings and a greater prevalence of uncontrolled hypertension, highlighting the need for strategies to manage blood pressure during such crises.
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Unlabelled: The first Fragility Hip Fracture Registry has been established in Greece. The in-hospital length of stay was 10.8 days and was significantly influenced by the delayed surgical fixation.

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Piriformis preserving posterior approach STAR for primary and primary complex total hip arthroplasty: Excellent safety and efficacy in a single blinded prospective single surgeon cohort of 522 patients with a mean follow-up of 2 years.

SICOT J

September 2024

Academic Orthopaedic Department, Aristotle University Medical School, General Hospital Papageorgiou, Ring Road Efkarpia, Thessaloniki 56403, Greece - Centre of Orthopaedic and Regenerative Medicine (CORE), Center for Interdisciplinary Research and Innovation (CIRI)-Aristotle University of Thessaloniki (AUTH), Balkan Center, Buildings A & B, 10th km Thessaloniki-Thermi Rd, P.O. Box 8318, Thessaloniki 57001, Greece - Tsiridis Orthopaedic Institute - ICAROS Clinic, Thessaloniki 55535, Greece.

Introduction: STAR (Superior Transverse Anatomic Reconstruction), a piriformis-preserving posterior approach, has not been extensively studied. Our study aimed to assess the STAR approach's safety and efficacy by recording postoperative complication rates and measuring implantation accuracy in a single surgeon prospective cohort with a mean follow-up of two years.

Methods: The study involved 522 patients with elective primary or complex primary total hip arthroplasty (THA) performed by a senior surgeon using the STAR approach between 2019 and 2023.

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Fertility-sparing treatment and follow-up in patients with cervical cancer, ovarian cancer, and borderline ovarian tumours: guidelines from ESGO, ESHRE, and ESGE.

Lancet Oncol

November 2024

Université Paris Saclay, Paris, France; Department of Reproductive Medicine and Fertility Preservation, Hopital Antoine Béclère, Clamart, France; Department of Reproductive Medicine and Fertility Preservation, Hopital Jean Verdier, Bondy, France.

Article Synopsis
  • - The European Society of Gynaecological Oncology, alongside other societies, created evidence-based guidelines for fertility-sparing strategies in patients with cervical and ovarian cancers, as well as borderline ovarian tumors.
  • - These guidelines were developed through a thorough literature review and involved a diverse group of 25 experts in multiple medical fields, ensuring a comprehensive approach.
  • - Prior to release, the guidelines were vetted by 121 independent cancer care professionals and patient representatives, addressing key aspects of initial management, fertility optimization, and future pregnancy desires.
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Article Synopsis
  • Trachoma is the leading infectious cause of blindness globally, primarily caused by serovars A-C of the bacterium Chlamydia trachomatis (Ct).
  • The disease spreads through direct or indirect contact with infected ocular and nasal secretions, often in areas with poor hygiene and crowded living conditions.
  • Chronic inflammation from repeated infections in early childhood can lead to severe complications like conjunctival scarring, trichiasis, corneal opacity, and ultimately, visual impairment.
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Background/objectives: Failure to thrive (FTT) is mostly caused by insufficient consumption of nutrient-rich food, recurrent infections like diarrhea and intestinal worms, substandard caregiving practices, and limited availability of health and other vital services. Furthermore, there was a correlation between the educational level of mothers and the occurrence of FTT in children aged 6-12 months. Thus, the objective of the current research is twofold: (i) to investigate other factors related to FTT and (ii) to evaluate the impact of them on FTT in Sub-Saharan African countries and their urban areas.

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It is established that diabetes mellitus (DM) is characterized by increased cardiovascular risk associated with subclinical atherosclerosis as well as microvascular alterations. Laser speckle contrast analysis (LASCA) is an innovative, non-invasive method for assessing skin microvascular function. We sought to assess skin microvascular function in patients with type 2 DM and matched controls.

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The Impact of Laparoscopic Surgery on Fertility Outcomes in Patients with Minimal/Mild Endometriosis.

J Clin Med

August 2024

1st University Department in Obstetrics and Gynecology, Papageorgiou General Hospital, School of Medicine, Aristotle University of Thessaloniki, 56429 Thessaloniki, Greece.

Minimal/mild endometriosis (MME) is independently associated with reduced fecundity rates. In this review article, we discuss the role of laparoscopic surgery in enhancing the fertility outcomes of patients with MME. Laparoscopic management of MME enhances fecundity and increases the chances of spontaneous conception in appropriately selected cases.

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Mesh-augmented hernia repair is the gold standard in abdominal wall and hiatal/diaphragmatic hernia management and ranks among the most common procedures performed by general surgeons. However, it is associated with a series of drawbacks, including recurrence, mesh infection, and adhesion formation. To address these weaknesses, numerous biomaterials have been investigated for mesh coating.

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Background: The use of sentinel lymph node biopsy (SLNB) for high-risk cutaneous squamous cell carcinoma (CSCC) is not yet clearly documented, especially for the head and neck area, due to its rich and cross-branching lymphatic system. We present the first prospective randomized study on the use of SLNB in high-risk CSCCs of the head and neck.

Methods: Seventy-six patients with high-risk CSCCs of the head and neck were randomly divided into two groups: A (n = 38) and B (n = 38).

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Introduction Primary knee osteoarthritis (OA) is a multifactorial degenerative joint disorder characterized by articular cartilage degradation. Matrix metalloproteinases (MMPs) have been reported to play a vital role in OA pathogenesis, significantly contributing to extracellular matrix (ECM) catabolism. The purpose of this study is to investigate the association of MMP-2 -1575G/A (rs243866), MMP-9 836A/G (rs17576), and MMP-13 -77A/G (rs2252070) gene polymorphisms with knee OA in the Greek population.

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