103 results match your criteria: "General Hospital "G. Hatzikosta" of Ioannina[Affiliation]"

Purpose: The metabolic management of ischemic heart disease represents a promising new therapeutic approach for acute coronary syndromes. Trimetazidine has been suggested to exert anti-ischemic properties on myocardium without affecting myocardial oxygen consumption or supply. The aim of this study was to investigate whether the administration of trimetazidine, as an adjunct to conventional treatment, decreases QT dispersion in patients with acute myocardial infarction (AMI).

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Article Synopsis
  • The study examined the impact of oxygen-derived free radicals on stomach damage caused by haemorrhagic shock and the protective effects of scavengers like allopurinol and ranitidine.
  • Forty-five rabbits were subjected to a 30-minute haemorrhagic shock followed by blood reinfusion, and their gastric health was evaluated post-treatment.
  • Results showed that while all control animals had gastric lesions, those pre-treated with scavengers had significantly smaller lesions, highlighting the protective role of oxygen radical antagonists.
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