476 results match your criteria: "Geelong Hospital[Affiliation]"

Stroke in critically ill patients with respiratory failure due to COVID-19: Disparities between low-middle and high-income countries.

Heart Lung

October 2024

Division of Neuroscience Critical Care, Departments of Neurology, Neurosurgery, and Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Article Synopsis
  • A study was conducted to compare stroke incidences and mortality rates in critically ill COVID-19 patients from low-and middle-income countries (LMICs) and high-income countries (HICs).
  • The results showed that stroke incidence was significantly higher in LMICs (35.7 per 1000 admitted-days) compared to HICs (17.6 per 1000 admitted-days), with patients from LMICs also facing higher mortality rates (43.6% vs. 29.2%).
  • The findings highlight the need for better stroke diagnosis and healthcare resource allocation in LMICs, as both higher income status and the presence of stroke are associated with increased risk of death
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Prevalence and outcomes of patients with SMuRF-less acute coronary syndrome undergoing percutaneous coronary intervention.

Open Heart

June 2024

Centre of Cardiovascular Research and Education in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.

Article Synopsis
  • - The study examined patients with acute coronary syndrome (ACS) lacking standard modifiable risk factors (SMuRFs) like diabetes and smoking to assess their prevalence and health outcomes compared to those with SMuRFs.
  • - Out of nearly 19,000 patients, 14.4% were classified as SMuRF-less, experiencing more severe initial cardiac events but showing similar 30-day mortality rates as patients with SMuRFs.
  • - Over a median follow-up of 7 years, SMuRF-less patients had a 13% lower long-term mortality risk, indicating they might have better outcomes over time despite their acute presentations.
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Use of point-of-care ultrasound during cardiac arrest in the intensive care unit: A cross-sectional survey.

Aust Crit Care

January 2025

Intensive Care Unit, Austin Hospital, Heidelberg, VIC, Australia; Department of Surgery and Department of Intensive Care, University of Melbourne, Parkville, VIC, Australia; Department of Epidemiology and Preventive Medicine, Monash University, VIC, Australia.

Background: There is growing interest in the use of point-of-care ultrasound during cardiac arrest, but few studies document its use in the intensive care unit.

Objective: We hypothesised this may reflect a low prevalence of use of point-of-care ultrasound during cardiac arrest or negative attitudes towards its use. We aimed to determine the self-reported prevalence, attitudes towards, and barriers to use of point-of-care ultrasound during cardiac arrest in the intensive care unit.

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Background: Patient outcomes following low-trauma hip fracture are suboptimal resulting in increased healthcare costs and poor functional outcomes at 1 year. Providing early and intensive in-hospital physiotherapy could help improve patient outcomes and reduce costs following hip fracture surgery. The HIP fracture Supplemental Therapy to Enhance Recovery (HIPSTER) trial will compare usual care physiotherapy to intensive in-hospital physiotherapy for patients following hip fracture surgery.

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Objective: To determine (i) the prevalence of overweight and obesity among children presenting to all EDs in a large regional Australian city and (ii) whether age, sex, socioeconomic status (SES) or hospital setting (public vs private) were associated with overweight and obesity.

Methods: This prospective observational study included children aged ≥2 and <18 years who presented to any of three EDs over an 18 month period who had their height and weight measured. Age, sex and residential postcode were collected.

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Introduction: Hip fractures result in substantial health impacts for patients and costs to health systems. Many patients require prolonged hospital stays and up to 60% do not regain their prefracture level of mobility within 1 year. Physical rehabilitation plays a key role in regaining physical function and independence; however, there are no recommendations regarding the optimal intensity.

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Ketamine is commonly used for procedural sedation anaesthesia in paediatric patients undergoing painful procedures in the ED. Ketamine's safety profile is excellent, but ketamine-associated vomiting (KAV) is common. Routine ondansetron prophylaxis could reduce KAV incidence.

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Background: The prognostic significance of non-disabling relapses in people with relapsing-remitting multiple sclerosis (RRMS) is unclear.

Objective: To determine whether early non-disabling relapses predict disability accumulation in RRMS.

Methods: We redefined mild relapses in MSBase as 'non-disabling', and moderate or severe relapses as 'disabling'.

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Comparative effectiveness in multiple sclerosis: A methodological comparison.

Mult Scler

March 2023

CORe, Department of Medicine, University of Melbourne, Melbourne, VIC, Australia/Neuroimmunology Centre, Department of Neurology, Royal Melbourne Hospital, Melbourne, VIC, Australia.

Background: In the absence of evidence from randomised controlled trials, observational data can be used to emulate clinical trials and guide clinical decisions. Observational studies are, however, susceptible to confounding and bias. Among the used techniques to reduce indication bias are propensity score matching and marginal structural models.

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Objectives: Investigate the characteristics of wrist, hand and finger (WHF) injuries in Australian footballers presenting to EDs and determine if injury profiles differed between females and males, and between children and adults.

Methods: In this prospective observational study that took place during an entire football season, patients attended 1 of 10 EDs in Victoria, Australia with a WHF injury sustained while playing Australian football. Data were extracted from patient medical records by trained researchers.

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Trends in Intra-Aortic Balloon Pump Use in Cardiogenic Shock After the SHOCK-II Trial.

Am J Cardiol

March 2023

Centre of Cardiovascular Research and Education in Therapeutics (CCRET), School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia; Baker Heart and Diabetes Institute, Melbourne, Australia.

Myocardial infarction complicated by cardiogenic shock (MI-CS) has a poor prognosis, even with early revascularization. Previously, intra-aortic balloon pump (IABP) use was thought to improve outcomes, but the IABP-SHOCK-II (Intra-aortic Balloon Pump in Cardiogenic Shock-II study) trial found no survival benefit. We aimed to determine the trends in IABP use in patients who underwent percutaneous intervention over time.

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Objective: Investigate the economic consequences of injuries to female Australian footballers from a health sector and societal perspective.

Methods: This prospective observational study invited 242 females to complete an online questionnaire 3-6 months following an Australian football injury which involved presentation to an ED in Victoria, Australia. The questionnaire inquired regarding healthcare use, time off work, return to playing football and extent of recovery following injury.

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Assault is the leading preventable cause of death, traumatic brain injury (TBI), and associated mental health problems. The COVID-19 pandemic has had a profound impact on patterns of interpersonal violence across the world. In this retrospective cross-sectional study, we analysed medical records of 1232 assault victims (domestic violence: 111, random assault: 900, prison assault: 221) with head injuries who presented to the emergency department (ED) at St Vincent's Hospital in Melbourne, Australia, a city with one of the longest and most severe COVID-19 restrictions worldwide.

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Acute burn care and outcomes at the Hospital Nacional Guido Valadares (HNGV), Timor-Leste: A 7-year retrospective study.

Medicine (Baltimore)

December 2022

Department of Clinical Sciences in Lund, Pediatric Surgery, Skåne University Hospital in Lund, Faculty of Medicine, Lund University, Lund, Sweden.

The purpose of this study was to describe the epidemiology of patients presenting with acute burns and undergoing admission at Hospital Nacional Guido Valadares (HNGV) in Dili, Timor-Leste in the period 2013 to 2019. HNGV is the only tertiary referral hospital in Timor-Leste. This was a retrospective study involving all acute burn patients admitted to the surgical wards of HNGV from 2013 to 2019.

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Introduction: Correctly identifying people with suspected stroke is essential for ensuring rapid treatment. Our aims were to determine the sensitivity of emergency dispatcher and paramedic identification of patients with stroke, the factors associated with correct identification, and whether there were any implications for hospital arrival times.

Methods: Observational study using patient-level data from the Australian Stroke Clinical Registry (2015-2017) linked with ambulance and emergency department records for the state of Victoria.

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Cryotherapy versus Laser Does Not Influence Anatomic Success after Vitrectomy for Primary Rhegmatogenous Retinal Detachment Repair: Registry Analysis of 2413 Patients.

Ophthalmol Retina

November 2022

Westmead and Central Clinical Schools, Specialty of Ophthalmology and Eye Health, The University of Sydney, Sydney, New South Wales, Australia; Department of Ophthalmology, Faculty of Medicine, Health and Human Sciences, Macquarie University Hospital, Sydney, New South Wales, Australia; Department of Ophthalmology, Westmead Hospital, Westmead, Australia. Electronic address:

Purpose: To determine whether a difference exists between cryotherapy and endolaser photocoagulation retinopexy in terms of the rates of anatomic success after primary rhegmatogenous retinal detachment (RRD) repair with pars plana vitrectomy (PPV).

Design: Registry-based, nonrandomized, observational cohort study.

Subjects: Eyes with primary RRD in a binational retinal surgery registry that underwent repair with PPV and had a minimum of 3 months of follow-up.

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Article Synopsis
  • This study looks at how to predict long-term disability in people with multiple sclerosis (MS) after they show signs of worsening over six months.
  • Researchers checked data from thousands of patients to figure out who is more likely to have lasting problems.
  • They found that things like age, sex, and how MS affects the person can help tell if someone will continue to get worse, which can help doctors in future treatments.
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Association of Latitude and Exposure to Ultraviolet B Radiation With Severity of Multiple Sclerosis: An International Registry Study.

Neurology

June 2022

From the CORe (M.V., I.D., C.M., P.D.M.P., T.K.), Department of Medicine, University of Melbourne, Australia; Melbourne MS Centre (M.V.), Department of Neurology, Faculty of Medicine, P.J. Safarik University, Kosice, Slovakia; Melbourne MS Centre (P.D.M.P., T.K.), Department of Neurology, Royal Melbourne Hospital, Australia; Department of Neurology and Center of Clinical Neuroscience (D.H., E.K.H.), First Faculty of Medicine, Charles University in Prague and General University Hospital, Czech Republic; Department of Medical and Surgical Sciences and Advanced Technologies (F.P.), GF Ingrassia; Multiple Sclerosis Center (F.P.), University of Catania, Italy; Dokuz Eylul University (S.O.), Konak/Izmir, Turkey; Hospital Universitario Virgen Macarena (G. Izquierdo, S.E.), Sevilla, Spain; Isfahan Neurosciences Research Center (INRC) (V.S.), Isfahan University of Medical Sciences (IUMS), Iran; Department of Neuroscience, Imaging, and Clinical Sciences (M.O.), University G. D'Annunzio, Chieti; IRCCS Istituto Delle Scienze Neurologiche di Bologna (A.L.); Dipartimento di Scienze Biomediche e Neuromotorie (A.L.), Universita di Bologna, Italy; Division of Neurology (R. Alroughani), Department of Medicine, Amiri Hospital, Sharq, Kuwait; CHUM MS Center and Universite de Montreal (A.P., C.L., M.G., P.D.), Quebec, Canada; Medical Faculty (M.T.), Ondokuz Mayis University, Samsun; KTU Medical Faculty Farabi Hospital (C. Boz), Trabzon, Turkey; Neuro Rive-Sud (F.G.), Longueuil, Quebec, Canada; Azienda Ospedaliera Universitaria di Modena (P.S.); Department of Biomedical (D.F.), Metabolic and Neurosciences, University of Modena and Reggio Emilia, Italy; CISSS Chaudière-Appalache (P.G.), Levis, Quebec, Canada; Central Clinical School (H.B.), Monash University; Department of Neurology (H.B., O.S.), The Alfred Hospital; Department of Neurology (K.B., O.S.), Box Hill Hospital, Eastern Health; Monash University (K.B., O.S.), Melbourne, Australia; Nehme and Therese Tohme Multiple Sclerosis Center (B.I.Y.), American University of Beirut Medical Center, Lebanon; Hacettepe University (R.K.), Ankara, Turkey; Zuyderland Medical Centre (O. Gerlach), Department of Neurologie, Dr. H. van der Hoffplein 1, Sittard-Geleen, the Netherlands; School of Medicine and Public Health (J.L.-S.), University Newcastle; Department of Neurology (J.L.-S.), John Hunter Hospital, Hunter New England Health, Newcastle, Australia; MS Center (D.M.), Neurology Unit, Garibaldi Hospital, Catania; IRCCS Mondino Foundation (R.B.), Pavia, Italy; Cliniques Universitaires Saint-Luc (V.V.P.), Brussels; Université Catholique de Louvain (V.V.P.), Belgium; Ospedali Riuniti di Salerno (G. Iuliano); UOC Neurologia (E. Cartechini), Azienda Sanitaria Unica Regionale Marche-AV3, Macerata, Italy; Hospital de Sao Joao (M.J.S.), Universidade Fernando Pessoa, Porto, Portugal; Nemocnice Jihlava (R. Ampapa), Jihlava, Czech Republic; Brain and Mind Centre (M.B.), Sydney, Australia; Royal Victoria Hospital (S.E.H.), Belfast, UK; Hospital Germans Trias I Pujol (C.M.R.-T.), Badalona, Spain; Liverpool Hospital (S.H.), Sydney, Australia; Liverpool Hospital and Ingham Institute (S.H.), Australia; Azienda Ospedaliera di Rilievo Nazionale San Giuseppe Moscati Avellino (D.L.A.S.), Italy; Kommunehospitalet (T.P.), Aarhus, Denmark; Monash Medical Centre (E.G.B.), Melbourne; Flinders University (M.S.), Adelaide, Australia; University College Dublin and St. Vincent's University Hospital (C. McGuigan), Ireland; University of Queensland (P.A.M.); Royal Brisbane and Women's Hospital (P.A.M.), Australia; Department of Medicine and Surgery (F.G.), University of Parma; Department of Emergency and General Medicine (F.G.), Parma University Hospital, Italy; Hospital Italiano (E. Cristiano), Buenos Aires, Argentina; CSSS Saint-Jérôme (J.P.), Saint-Jerome, Quebec, Canada; Royal Hobart Hospital (B.V.T.), Australia; Hospital de Galdakao-Usansolo (J.L.S.Ã.-M.), Galdakao, Spain; Department of Neurology (G.L.), Ghent University Hospital, Corneel Heymanslaan 10; University Hospital Ghent (L.V.H.), Ghent, Belgium; Westmead Hospital (S.V.), Sydney; Austin Health (R.A.M.), Melbourne, Australia; South East Trust (O. Gray), Belfast, UK; Instituto de Investigación Sanitaria Biodonostia (J.O.), Hospital Universitario Donostia, San Sebastián, Spain; Hospital Fernandez (N.D.), Capital Federal, Argentina; Universidade Metropolitana de Santos (Y.D.F.), Santos, Brazil; and Geelong Hospital (C.S.), Geelong, Australia.

Article Synopsis
  • The study aimed to explore how the latitude of residence and UVB radiation exposure affects the severity of multiple sclerosis (MS) among patients, using data from the MSBase registry.
  • Results indicated that patients living at higher latitudes (above 40°) experienced more severe MS symptoms, while this trend was not observed in those living below this latitude.
  • Additionally, lower UVB exposure during childhood (ages 6 and 18) was linked to faster progression of disability in MS, suggesting the importance of environmental factors in disease severity.
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We describe the management of a colo-atmospheric fistula following extensive debridement for abdominal wall necrotising fasciitis. This was a novel technique performed with VAC dressing and a plastic syringe to isolate the fistula from the surround tissue.

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Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase II randomised placebo-controlled double-blind multicentre trial.

Stroke Vasc Neurol

April 2022

Department of Medicine and Neurology, Melbourne Brain Centre at The Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria, Australia.

Rationale: Haematoma growth is common early after intracerebral haemorrhage (ICH), and is a key determinant of outcome. Tranexamic acid, a widely available antifibrinolytic agent with an excellent safety profile, may reduce haematoma growth.

Methods And Design: Stopping intracerebral haemorrhage with tranexamic acid for hyperacute onset presentation including mobile stroke units (STOP-MSU) is a phase II double-blind, randomised, placebo-controlled, multicentre, international investigator-led clinical trial, conducted within the estimand statistical framework.

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Article Synopsis
  • Transanal total mesorectal excision (taTME) is a new surgical technique for rectal dissection, but the learning curve for this procedure is not clearly defined, raising concerns about complications and safety.
  • A systematic review of studies from 2010-2020 revealed that after mastering the technique, clinical outcomes improved significantly, with fewer adverse events and better surgical quality in the advanced learning curve group compared to the early learning curve group.
  • The findings suggest that taTME should be performed by well-trained surgical teams on carefully selected patients to ensure optimal results and ongoing improvement.
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Rapidly recurrent prostatic obstruction due to granulomatosis with polyangiitis.

Urol Case Rep

November 2021

Anatpath, 120 Gardenvale Road, Gardenvale, VIC, 3185, Australia.

Granulomatosis with polyangiitis (GPA) is a rare cause of prostatitis. Our case illustrates a case of granulomatous prostatitis secondary to unrecognised GPA requiring multiple surgical interventions. The patient presented with lower urinary tract symptoms.

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Background: Family-centred critical care recognises the impact of a loved one's critical illness on his relatives. Open visiting is a strategy to improve family satisfaction and psychological outcomes by permitting unrestricted or less restricted access to visit their family member in the intensive care unit (ICU). However, increased family presence may result in increased workload and a risk of burnout for ICU staff.

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