The Effect of Birth Weight on Fattening Performance, Meat Quality, and Muscle Fibre Characteristics in Lambs of the Karayaka Native Breed.

This investigation aimed to assess the influence of birth weight on post-weaning fattening performance, meat quality, muscle fibre characteristics, and carcass traits in Karayaka lambs. The study categorized the lambs into three distinct groups based on birth weight: low birth weight (LBW), medium birth weight (MBW), and high birth weight (HBW). Throughout the fattening phase, the lambs were given access to food and water, culminating in the slaughter at the end of the study.

Isolation of phenolic compounds from eco-friendly white bee propolis: Antioxidant, wound-healing, and anti-Alzheimer effects.

This study presents the first findings regarding extraction, isolation, enzyme inhibition, and antioxidant activity. The oral mucosal wound-healing process was investigated using propolis water extract (PWE) incubation with gingival fibroblast cells and concluded that propolis was effective on the oral mucosal wound-healing pattern compared to untreated controls. Additionally, phenolic compounds (fraxetin, apigenin, galangin, pinobanksin, chrysin, etc.

Combination of navitoclax (Bcl-2 and Bcl-xL inhibitor) and Debio-0932 (Hsp90 inhibitor) suppresses the viability of prostate cancer cells via induction of apoptotic signaling pathway.

Prostate cancer is one of the most common cancers in men. Given the diverse nature of prostate cancer and its tendency to respond differently to various treatments, combination therapies are often employed to enhance outcomes. In this study, the synergetic efficiency of chemotherapeutic drug Navitoclax and heat shock protein 90 (Hsp90) inhibitor Debio-0932 was evaluated in human prostate cancer cell line (PC3).

Determination of chromium in foodstuffs by using novel adsorbent in vortex assisted-dispersive solid phase micro-extraction method: An application of multivariate techniques.

A new graft copolymer composed of polystyrene and polylinoleic acid (PLinas) with the sodium salt of iminodiacetate (Ida) was synthesized and used as an adsorbent. The vortex-assisted dispersive solid-phase micro-extraction (VA-dSPµE) method was used for the extraction and pre-concentration of chromium. Multivariate methodologies, such as factorial design and 3D surface plots, were applied for screening and optimizing effective extraction parameters.

Association between dental caries and adherence to the Mediterranean diet, dietary intake, and body mass index in children.

Background: Children with healthier nutritional status are less likely to develop severe caries than those with a high-sugar content diet. Studies evaluating dental caries and nutritional status in school-age children have generally focused on dietary intake, diet quality, or anthropometric measures, and the number of studies evaluating them together is limited.

Objective: It was aimed to evaluate the relationship between dental caries adherence to the Mediterranean Diet (MD), dietary intake, and Body Mass Index (BMI) in school-age children.

Global trends in incidence and prevalence of achalasia, 1925-2021: A systematic review and meta-analysis.

Background: Achalasia poses a significant socioeconomic burden, yet global trends remain undocumented. This study aims to describe the worldwide trends in the incidence and prevalence of achalasia from 1925 to 2021 and explore their correlation with various factors through a comprehensive systematic review.

Methods: We searched the PubMed/MEDLINE, Embase, and Cochrane databases from inception to 30 June 2023, to identify studies reporting the incidence or prevalence of achalasia in the general population.

Evaluation of Interstitial Lung Diseases with Deep Learning Method of Two Major Computed Tomography Patterns.

Background: Interstitial lung diseases (ILD) encompass various disorders characterized by inflammation and/or fibrosis in the lung interstitium. These conditions produce distinct patterns in High-Resolution Computed Tomography (HRCT).

Objective: We employ a deep learning method to diagnose the most commonly encountered patterns in ILD differentially.

Effect of high voltage electrical stimulation in temporomandibular disorders: a randomized controlled trial.

Objective: To examine the effects of high voltage electrical stimulation (HVES) on pain intensity, maximum mouth opening (MMO), cervical mobility, head position, pressure pain thresholds (PPTs), bite force, joint sounds, and jaw muscle strength in individuals with temporomandibular disorders (TMDs).

Methods: Thirty-four individuals with TMDs were randomly divided into the exercise group (EG) ( = 17) and the HVES group (HG) ( = 17). For 4 weeks, EG received exercise therapy alone, while HG received HVES (12 sessions in total, 3 days a week to anterior temporalis and masseter) in conjunction with exercise.

A Novel Ensemble Framework for Multi-Classification of Brain Tumors Using Magnetic Resonance Imaging.

Brain tumors can have fatal consequences, affecting many body functions. For this reason, it is essential to detect brain tumor types accurately and at an early stage to start the appropriate treatment process. Although convolutional neural networks (CNNs) are widely used in disease detection from medical images, they face the problem of overfitting in the training phase on limited labeled and insufficiently diverse datasets.

Evaluation of the Relationship Between Mobile Phone Usage and miRNA-574-5p and miRNA-30C-5p Levels in Thyroid Cancer Patients.

Objectives: This study aimed to evaluate the relationship between mobile phone usage and miRNA-574-5p and miRNA-30C-5p levels in patients diagnosed with differentiated thyroid cancer (DTC).

Methods: Fifty patients diagnosed with DTC and 50 healthy volunteers were included in the study. miRNA-574-5p and miRNA-30C-5p gene expression levels in the blood of all subjects were analyzed by real time-polymerase chain reaction, and a questionnaire including various questions was administered to both groups.

Formulation of hesperidin-loaded in situ gel for ocular drug delivery: a comprehensive study.

Background: Allergic conjunctivitis is one of the most common eye disorders. Different drugs are used for its treatment. Hesperidin is an active substance isolated from Citrus sinensis L.

1,3-Diaryl Triazenes Incorporating Disulfonamides Show Both Antiproliferative Activity and Effective Inhibition of Tumor-associated Carbonic Anhydrases IX and XII.

Aim: The aim of this study was to synthesize a library of novel di-sulfa drugs containing 1,3- diaryltriazene derivatives TS (1-13) by conjugation of diazonium salts of primary sulfonamides with sulfa drugs to investigate the cytotoxic effect of these new compounds in different cancer types and to determine their inhibitory activity against tumor-associated carbonic anhydrases IX and XII.

Materials And Methods: A carbonic anhydrase inhibitory activity of the obtained compounds was evaluated against four selected human carbonic anhydrase isoforms (hCA I, hCA II, hCA IX and hCA XII) by a stoppedflow CO hydrase assay. In addition, , cytotoxicity studies were applied by using A549 (lung cancer), BEAS-2B (normal lung), MCF-7 (breast cancer), MDA-MB-231 (breast cancer), CRL-4010 (normal breast epithelium), HT-29 (colon cancer), and HCT -116 (colon cancer) cell lines.

The relationship between passion and athlete identity in sport: the mediating and moderating role of dedication.

Background: In addition to the fact that the concept of passion in sports plays a significant role in the formation of the identity concept of athletes, the dedication of athletes to the sports branches they are interested in also has a significant impact on their passion for the sport they are interested in as well as their identity as an athlete. In this direction, the research aims to investigate the role of dedication as a mediator and moderator in the relationship between athlete identity and passion in sport.

Methods: The research was designed using the quantitative research technique of relational surveying.

Understanding university students' attitudes and preferences for internet-based mental health interventions.

Internet-based interventions are recognised as a practical approach to address mental health issues. The acceptance and utilisation of such interventions are closely linked to user attitudes and preferences. This study aims to examine the predictors of university students' attitudes towards internet-based interventions.

A colorimetric immunoassay for the detection of human vascular endothelial growth factor 165 (VEGF) based on anti-VEGF-iron oxide nanoparticle conjugation.

Vascular endothelial growth factor (VEGF) is an indispensable element in many physiological processes, while alterations in its level in the circulating system are signs of pathology-associated diseases. Therefore, its precise and selective detection is critical for clinical applications to monitor the progression of the pathology. In this study, an optical immunoassay biosensor was developed as a model study for detecting recombinant VEGF.

Tree-based algorithms for spatial modeling of soil particle distribution in arid and semi-arid region.

Accurate estimation of particle size distribution across a large area is crucial for proper soil management and conservation, ensuring compatibility with capabilities and enabling better selection and adaptation of precision agricultural techniques. The study investigated the performance of tree-based models, ranging from simpler options like CART to sophisticated ones like XGBoost, in predicting soil texture over a wide geographic region. Models were constructed using remotely sensed plant and soil indexes as covariates.

Energy security-related risks and the quest to attain USA's net-zero emissions targets by 2050: a dynamic ARDL simulations modeling approach.

The Russia-Ukraine war and other similar conflicts across the globe have heightened risks to the United States of America's (USA's) energy security. However, little is known about the severity of the effect of energy security risks on the USA's quest to attain net-zero emissions targets by 2050. To this end, we examine the effect of energy security risks on the load capacity factor (LCF) in the USA.

Adaptation of the Gerontological Nursing Competence (GeroNursingCom) instrument to Turkish: Validity and reliability study.

Aim: The aim of this study was to conduct a Turkish validity and reliability study of the Gerontological Nursing Competence Scale and to adapt the scale to Turkish culture.

Background: As the number of older people increses, gerontological nursing requires specialized expertise in older people care. High-quality basic education and further education guarantee good competence in gerontological care.

Bond strength comparison of a fiber-reinforced composite resin: Different dentin conditions and preparation techniques.

This study aimed to compare the bond strength of a fiber-reinforced composite resin with traditional and bulk-fill composite resins under different dentin conditions and preparation techniques. Eighty molar teeth, excluding the mesio-distal half of the occlusal dentin surfaces of each teeth, were isolated with acid-resistant nail varnish and stored in a demineralisation solution (pH 4.5).

Epigenetic insights into Familial Mediterranean Fever: Increased RGS10 expression and histone modifications accompanies inflammation in familial Mediterranean fever disease.

Background: Familial Mediterranean fever (FMF) is an autosomal recessive autoinflammatory disease characterized by recurring fever, erythema, joint pain, and abdominal discomfort during acute episodes. While FMF patients typically share MEFV gene mutations, they display varying clinical manifestations, suggesting the involvement of modifying genes, epigenetic mechanisms, or environmental factors. G protein regulator signal 10 (RGS10), a member of the RGS protein family, exhibits anti-inflammatory effects in autoinflammatory diseases.

Evaluating the role of financial globalization and oil consumption on ecological quality: A new perspective from quantile-on-quantile granger causality.

Global warming has progressed into a pressing global concern, primarily driven by human activities. To address this issue, it is vital to identify the key drivers of ecological quality and develop effective policies in response. Consequently, this study seeks to empirically examine the causal effect of financial globalization, economic growth, economic policy uncertainty, and oil consumption on the load capacity factor (LF) in Brazil.

The caffeine dilemma: unraveling the intricate relationship between caffeine use disorder, caffeine withdrawal symptoms and mental well-being in adults.

Objective: This study aimed to explore the relationship between caffeine use disorder (CUD), caffeine withdrawal symptoms and the prevalence of depression, anxiety and stress (DASS) in adults.

Design: The study utilised a cross-sectional design to assess the relationships between CUD, caffeine withdrawal symptoms and DASS.

Setting: Participants' CUD was evaluated through the Caffeine Use Disorder Questionnaire (CUDQ), while the Depression Anxiety Stress Scale-21 (DASS-21) measured DASS levels.

Scapular muscle endurance, shoulder pain, and functionality in patients with rotator-cuff-related shoulder pain: a matched, case-control study.

Background: Deficiency in scapular muscle endurance (SME) is a risk factor for rotator-cuff-related shoulder pain (RCRSP). However, the exact relationship among SME, pain, and functionality remains unclear. This study aims to compare SME, pain, and functionality in RCRSP patients to those in age-sex-matched healthy controls.

Dissipation behaviors of deltamethrin, emamectin benzoate and hexythiazox in grape under field conditions.

The objective of this study was to evaluate the dissipation kinetics of deltamethrin, emamectin benzoate, and hexythiazox in grapes. The QuEChERS method was employed and validated for the precise determination of these three pesticides using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Excellent linearity was observed with regression coefficients exceeding 0.