2,351 results match your criteria: "Gaziosmanpasa University.[Affiliation]"

This article presents an innovative approach for the task of isolated sign language recognition (SLR); this approach centers on the integration of pose data with motion history images (MHIs) derived from these data. Our research combines spatial information obtained from body, hand, and face poses with the comprehensive details provided by three-channel MHI data concerning the temporal dynamics of the sign. Particularly, our developed finger pose-based MHI (FP-MHI) feature significantly enhances the recognition success, capturing the nuances of finger movements and gestures, unlike existing approaches in SLR.

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Article Synopsis
  • A study evaluates patients with antibodies against myelin oligodendrocyte glycoprotein (anti-MOG-IgG), assessing their clinical, radiological, and demographic characteristics in relation to conditions like optic neuritis and myelitis.
  • Among the 104 participants, the majority were women, and the most common diagnoses included NMOSD, isolated optic neuritis, and ADEM, with a notable percentage showing symptoms resembling MS.
  • Findings indicate that older patients (>40 years) experienced more severe disability and poorer responses to treatment, highlighting the significance of anti-MOG-IgG in diagnosing NMOSD in patients without anti-NMO antibodies.
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Background/aim: Male infertility rises for many reasons, along with age; therefore, we aimed to research the characterization of aquaporin-3, 7, and 8 in human sperm belonging to different age groups.

Material And Methods: This study was conducted on sperm samples of men aged over 18 years. A total of 60 men were included in the study and divided into three age groups: group 1, age 18-25 years (n = 20); group 2, age 26-35 years (n = 20); and group 3, age ≥35 years (n = 20).

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Introduction: Postintensive care syndrome (PICS) is a combination of short-, medium- and long-term morbidities that occur in patients discharged from the Intensive care unit (ICU). ICU professionals have a crucial role in managing and understanding the PICS. This study aimed to develop the PICS Knowledge Test (PICS-KT), which measures ICU professionals' awareness and knowledge levels regarding PICS, and to determine its validity and reliability.

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Objective: The purpose of this study was to research the neutrophil-lymphocyte ratio (NLR), lymphocyte-to-C-reactive protein ratio (LCR), and Fournier's Gangrene Severity Index (FGSI) for predicting prognosis and mortality in patients with Fournier's gangrene (FG).

Material And Methods: Patients diagnosed with FG and treated in a tertiary referral hospital in the period from January 2013 to June 2020 were reviewed. LCR, FGSI, and NLR values were calculated.

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Introduction/aim: Turkey has experienced a heavy migration burden in recent years due to its location and benevolent policies. This study aimed to retrospectively examine and discuss the reports prepared for foreign nationals who requested assistance at the Forensic Medicine Department of Tokat Gaziosmanpaşa University Hospital in Tokat, which is located in the Middle Black Sea Region of Turkey, between 2014 and 2022.

Materials And Methods: This study retrospectively evaluated reports prepared between 2014 and 2022 in the outpatient clinics of Forensic Medicine at Tokat Gaziosmanpaşa University Hospital.

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Assessment of serum granulysin and cathepsin-L levels in vitiligo patients.

Rev Assoc Med Bras (1992)

May 2024

Gaziosmanpasa University, School of Medicine, Department of Dermatology and Venereology - Tokat, Turkey.

Objective: Cellular and humoral immunity plays a role in the pathogenesis of vitiligo. T lymphocytes and natural killer cells involved in cellular immunity carry out their cytotoxic activities through perforin/granzyme-dependent granule exocytosis, in which granulysin and cathepsin-L are also involved. The aim of this study was to investigate the possible role of serum granulysin and cathepsin-L in the etiopathogenesis of vitiligo and their association with disease activity and severity.

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Introduction: Postmenopausal osteoporosis (PMOP) is a common metabolic bone disorder manifested by low bone mineral density and increased fracture risks in postmenopausal women. Vascular endothelial growth factor (VEGF) has been shown to play an important role in bone formation. In this study, we investigated the potential association between the VEGF insertion/deletion (I/D) variant (rs35569394) and PMOP in a cohort of postmenopausal Turkish women.

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Today, laparoscopy is frequently used in abdominal emergencies such as acute appendicitis. There are several techniques used to close the appendiceal stump during laparoscopic appendectomy. We aimed to compare the use of handmade loop and Hem-o-lok used to close the appendiceal stump in public hospitals where resources are limited, in terms of surgical outcomes and cost.

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Medico-legal evaluation of deficiencies in the definition of wound depth in forensic reports: a retrospective study.

Eur Rev Med Pharmacol Sci

May 2024

Department of Forensic Medicine, Faculty of Medicine, Tokat Gaziosmanpasa University, Tokat, Turkey.

Objective: One of the most important parts of accurate wound definition is wound depth. In our study, we aimed to reveal the deficiencies in the depth of wound definition in the general forensic examination forms prepared in the emergency services and to increase the awareness of the physicians responsible for preparing the general forensic examination form.

Materials And Methods: In our study, we included cases from the years 2020 to 2021 that were evaluated by our team upon seeking assistance from the Department of Forensic Medicine at Tokat Gaziosmanpasa University Medical School.

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A new magnetic nano gel (MNG) was prepared from choline chloride/phenol deep eutectic solvent and magnetic amberlite XAD-7 nanocomposite. The dispersive solid phase micro extraction (dSPME) method was developed for seperation and preconcentration of Brilliant Blue FCF (BB) by the prepared MNG. In this study, firstly, the optimum DES type and mole ratio of DES were investigated before response surface methodology optimization.

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Climate change-induced alterations in temperature variation, ozone exposure, water salinity and acidification, and hypoxia might influence immunity and thus survival in diverse groups of animals from fish to mammals. Pyroptosis is a type of lytic pro-inflammatory programmed cell death, which participates in the innate immune response, and is involved in multiple diseases characterized by inflammation and cell death, mostly studied in human cells. Diverse extrinsic factors can induce pyroptosis, leading to the extracellular release of pro-inflammatory molecules such as IL-18.

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Background: This study aimed to evaluate the histopathological and biochemical effects of ketamine on penile tissues following ischemia-reperfusion injury induced by priapism.

Methods: Twenty-four male rats were randomized into three groups. Group 1 served as the control group.

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Objectives: To investigate the effects of increasing propolis doses on salivary glands exposed to radiotherapy (RT).

Methods: Thirty-seven rats were divided into 4 groups: The control group (G0, n: 7), G1 group (n: 10), G2 group (n: 10), and G3 group (n: 10). The rats in the G1 group received 15 Gray (Gy) RT only to the head and neck area.

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Article Synopsis
  • - Peganum harmala, commonly used in Algerian traditional medicine, was studied for its n-butanol extract’s effects on human breast cancer cells (MCF-7), focusing on cell growth, migration, and blood vessel formation (angiogenesis).
  • - The n-butanol extract showed significant cytotoxicity with an IC value of 8.68 μg/mL, reduced cell migration, and displayed strong anti-angiogenic effects, verified through both macroscopic and histological analyses.
  • - Analysis revealed 15 phenolic compounds in the extract, and its antioxidant properties indicate that the beneficial effects might stem from the combined action of these various polyphenolic classes.
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Gold standard method for the treatment of critical-sized bone defects is the autogenous bone grafting procedure. A number of new and potentially useful adjuncts currently are being investigated to enhance the success of bone grafting. We propose to evaluate the effect of the most known and easily obtained 2 biological materials, fat graft and platelet-rich plasma (PRP), on bone graft healing.

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Purpose: This study aims to determine the presence and morphology of triticeal cartilage (TrC) through autopsy cases and to examine its relationship with age, gender, and height, thus contributing to clinical practices and forensic perspective.

Materials And Methods:  Our study was conducted on a total of 84 autopsy cases between the ages of 20-90 years who came to Tokat Forensic Medicine Institute. The laryngeal region was palpated to determine whether TrC was present.

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Apoptotic effect of 5-fluorouracil-doxorubicin combination on colorectal cancer cell monolayers and spheroids.

Mol Biol Rep

May 2024

Department of Medical Laboratory Techniques, Tokat Vocational School of Health Services, Tokat Gaziosmanpasa University, 60000, Tokat, Turkey.

Background: Drug combination studies help to improve new treatment approaches for colon cancer. Tumor spheroids (3D) are better models than traditional 2-dimensional cultures (2D) to evaluate cellular responses to chemotherapy drugs. The cultivation of cancer cells in 2D and 3D cultures affects the apoptotic process, which is a major factor influencing the response of cancer cells to chemotherapeutic drugs.

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Background: The use of dental implants in the treatment of edentulous patients is increasing. Zirconia implants are an alternative to titanium implants, offering advantages in terms of aesthetics and biological compatibility. However, the number of artifacts observed on radiographic images with zirconia implants compared to titanium implants is yet to be determined.

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Neutrophil-Creatinine Index: A New Prognostic Factor for Severity of Acute Pancreatitis.

Medicina (Kaunas)

April 2024

Gastroenterology Department, Faculty of Medicine, Tokat Gaziosmanpasa University, 60030 Tokat, Turkey.

: Determining the severity of acute pancreatitis (AP) is the main goal in the early stage of AP. The aim of this study was to compare laboratory parameters and indices, including the neutrophil to lymphocyte ratio (NLR) and the neutrophil-creatinine index (NCI), at admission in order to predict the severity of AP. : Data from 421 patients who were admitted with a diagnosis of AP were collected retrospectively.

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Prevalence of Infectious Diseases in Children at Preschool Education Institutions and Stakeholder Opinions.

Children (Basel)

April 2024

Department of Childhood Development, Pazar Vocational School of Higher Education, Tokat Gaziosmanpaşa University, 60800 Tokat, Türkiye.

Preschool education institutions, where children have close contact and social interactions, can serve as potential environments for the transmission of infectious diseases. This issue poses a significant health concern, impacting both individual and public well-being. Thus, the present research set out to determine the prevalence of infectious diseases in preschool children and the views of parents and teachers on the prevention of infectious diseases.

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Background: Chromosomal microarray analysis is an essential tool for copy number variants detection in patients with unexplained developmental delay/intellectual disability, autism spectrum disorders, and multiple congenital anomalies. The study aims to determine the clinical significance of chromosomal microarray analysis in this patient group. Another crucial aspect is the evaluation of copy number variants detected in terms of the diagnosis of patients.

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This study employs a phenomenological approach to investigate the experiences of individuals who access services at a community mental health center (CHMC) in Türkiye The aim of this study is to comprehend the experiences of individuals who participate in psychosocial skills training at the CHMC. Thematic analysis of data from sixteen in-depth interviews revealed three main themes and eight sub-themes. Functionality theme emphasizes the positive impact of CHMC services and training on daily life and social functioning.

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The Effect of Stoma Site Marking on Stomal Complications: A Long-term Retrospective Study.

Adv Skin Wound Care

May 2024

Sevil Guler, PhD, RN, is Professor, Faculty of Nursing, Department of Surgical Nursing, Gazi University, Ankara, Turkey. Gulcan Eyuboglu, PhD, RN, is Research Assistant, Erbaa Faculty of Health Science, Department of Nursing, Fundamentals of Nursing, Gaziosmanpasa University, Tokat, Turkey. Also at Gazi University, Faculty of Nursing, Department of Fundamentals of Nursing, Zehra Gocmen Baykara, PhD, RN, is Professor. At Gazi University Health Research and Application Center Hospital, Stomatherapy Unit, Aysel Oren Hin, RN; Hülya Akdemir, RN; and Emine Akar, RN, are Stoma and Wound Care Nurses. Also at Gazi University, Sezai Leventoglu, MD, and Osman Yuksel, MD, are Professors, Faculty of Medicine, Department of General Surgery. The authors have disclosed no financial relationships related to this article. Submitted January 5, 2023; accepted in revised form March 14, 2023.

Objective: To identify the effect of stoma site marking on stoma-related complications.

Methods: The study sample included 639 individuals with stomas who were followed up in a stomatherapy unit in Turkey between January 1, 2017, and June 20, 2021. Researchers collected patient data from nursing records.

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