27 results match your criteria: "Gaziosmanpasa Research and Training Hospital[Affiliation]"

Evaluation of uterocervical angle in intrauterine device displacement cases.

Arch Gynecol Obstet

December 2024

Department of Obstetrics and Gynecology, University of Health Sciences, Gaziosmanpasa Research and Training Hospital, Istanbul, Turkey.

Purpose: Intrauterine device is one of the most preferred birth control method in the world. Being able to predict that the intrauterine device will not dislocate is very important in terms of preventing unwanted pregnancies. Here, we evaluated the role of uterocervical angle in displacement of intrauterine device and to determine whether it has a discriminative role for displacement.

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Can the efficacy of a medical treatment be predicted based on the type of idiopathic premature ventricular contraction?

J Electrocardiol

September 2024

Cardiology Department, Istanbul Medeniyet University Faculty of Medicine, Goztepe Training and Research Hospital, Dr. Erkin street, 34722 Istanbul, Turkey.

Background: Premature ventricular contractions (PVCs) are common arrhythmias with diverse clinical implications. This retrospective study aimed to evaluate the efficacy of medical treatments using various clinical, imaging, and electrocardiographic parameters in patients with idiopathic PVCs.

Methods: A total of 1051 patients with idiopathic PVCs were retrospectively analyzed.

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Article Synopsis
  • * An analysis of 829 bladder cancer cases revealed that 80.5% were conventional urothelial carcinoma, while 19.5% had variant histology, with squamous differentiation being the most common subtype in the latter.
  • * Key factors like tumor grade and invasion levels differed significantly between the variant and conventional groups, affecting diagnostic outcomes, but demographic factors like age and gender showed no significant differences.
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Pituitary abscess (PA), a rare complication following transsphenoidal (TS) surgery for pituitary adenoma with an incidence of 0.2%, poses a significant risk; carrying potential morbidity, recurrence, and the necessity for reoperation. Timely suspicion, diagnosis, and treatment are imperative.

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Introduction: Long-acting muscarinic antagonists (LAMA) or beta-2 agonists (LABA) have been recommended for symptom control in group A COPD patients as a first-line bronchodilator treatment in GOLD guidelines. However, there is no mention of priority/superiority between the two treatment options. We aimed to compare the effectiveness of these treatments in this group.

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Background and objective Emotional factors can affect stomach secretions, acid expression, and stomach motor functions. The coronavirus disease 2019 (COVID-19) pandemic was an emotionally difficult time for many individuals as the whole world faced a life-threatening disease for which definitive treatment is still not fully established. In light of this, the aim of this study was to compare the results of gastroscopies performed among individuals before and after the pandemic.

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Aim: The present study aims to establish the role of serum CGRP and SP levels in the disease pathophysiology in patients with dialysis headache not accompanied by primary or secondary headaches, and also whether there is a correlation between these vasoactive peptides and the severity of headache.

Method: This study was designed as prospective and multicenter. A total of 30 dialysis headache patients and 30 patients without headache as the control group in the Nephrology outpatient clinics which implement similar dialysis procedures were included in the study.

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Pneumopericardium is the presence of air in the pericardial sac. Pneumopericardium after pericardiocentesis has been rarely reported in the literature. In the present case, we report a patient who presented with tamponade physiology during COVID-19 and developed pneumopericardium after emergency pericardiocentesis.

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Aim: Apical prolapse is an important component of pelvic organ prolapse. The aim of our study was to investigate the effectiveness of laparoscopic lateral suspension (LLS) surgery, which we performed while sparing the uterus.

Methods: LLS surgery was performed on 62 patients due to apical prolapse, preserving their uterus.

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The aim of this study is to assess the extent of the increased intracranial pressure resulting from lateral decubitus and 45° downward positioning using sonographic optic nerve sheath diameter (ONSD) in patients undergoing laparoscopic transperitoneal nephrectomy. In addition, we evaluated the effect of the carbon dioxide pneumoperitoneum (COPP) on ONSD. Twenty-four adults were enrolled in this prospective observational study.

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Objective: To evaluate several lymphocyte subtypes with various parameters that can be applied easily and give fast results for their roles in evaluating the stage and prognosis of acute biliary pancreatitis.

Study Design: Case-control study.

Place And Duration Of Study: The Emergency Department of Istanbul Training and Research Hospital, and Gaziosmanpasa Research and Training Hospital, Turkey, between June 2020 and April 2021.

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Metacarpal squeezing reduces grip strength.

Hand Surg Rehabil

February 2022

Orthopedics and Traumatology, İstanbul Medeniyet University, Faculty of Medicine, Ünalan Mahallesi, D100 Karayolu Yanyol, 34700 Üsküdar, İstanbul, Turkey; Göztepe Prof. Dr. Süleyman Yalçın State Hospital, Eğitim Mahallesi, Dr. Erkin Caddesi, 34722 Kadıköy, İstanbul, Turkey. Electronic address:

Unduly tight plaster hand casts may narrow the metacarpal joint space, hindering rehabilitation. This study investigated how metacarpal narrowing affects grip strength. Forty-two adult volunteers with no other pathology were included.

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Objective: Diffuse gliomas, the most common primary malignant brain tumors, have been classified by the World Health Organization as class II-IV gliomas. After 2016, two mutations in the promoter region of the telomerase reverse transcriptase (TERT) gene were identified in addition to the IDH, 1p / 19q, and ATRX status.

Material And Method: We identified 84 patients with grade II-IV glioma with IDH, ATRX, 1p / 19q and TERT status.

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Objective: Exacerbations in patients with COPD may still be unpredictable, although the general risk factors have been well defined. We aimed to determine the role of a novel parameter, area under flow-volume loop, in predicting severe exacerbations.

Methods: In this single-centre retrospective cohort study, 81 COPD patients over 40 years of age with high grade of dyspnea (having a CAT score of ≥10) and a history of ≥1 moderate exacerbation in the previous year were included.

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Cytokine storm in severe COVID-19 pneumonia.

J Med Virol

September 2021

Department of Dermatology, Gaziosmanpasa Research and Training Hospital, University of Health Sciences, Istanbul, Turkey.

In this study, laboratorial parameters of hospitalized novel coronavirus (COVID-19) patients, who were complicated with severe pneumonia, were compared with the findings of cytokine storm developing in macrophage activation syndrome (MAS)/secondary hemophagocytic lymphohistiocytosis (sHLH). Severe pneumonia occurred as a result of cytokine storm in some patients who needed intensive care unit (ICU), and it is aimed to determine the precursive parameters in this situation. Also in this study, the aim is to identify laboratory criteria that predict worsening disease and ICU intensification, as well as the development of cytokine storm.

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COVID-19 Among Patients With Inflammatory Rheumatic Diseases.

Front Immunol

May 2021

Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.

Background: The course of novel coronavirus disease 2019 (COVID-19) has been of special concern in patients with inflammatory rheumatic diseases (IRDs) due to the immune dysregulation that may be associated with these diseases and the medications used for IRDs, that may affect innate immune responses.

Objective: In this cohort study, we aimed to report the disease characteristics and variables associated with COVID-19 outcome among Turkish patients with IRDs.

Methods: Between April and June, 2020, 167 adult IRD patients with COVID-19 were registered from 31 centers in 14 cities in Turkey.

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Changes in antimicrobial resistance and outcomes of health care-associated infections.

Eur J Clin Microbiol Infect Dis

August 2021

School of Medicine Department of Infectious Diseases and Clinical Microbiology, Koc University, Istanbul, Turkey.

To describe the change in the epidemiology of health care-associated infections (HAI), resistance and predictors of fatality we conducted a nationwide study in 24 hospitals between 2015 and 2018. The 30-day fatality rate was 22% in 2015 and increased to 25% in 2018. In BSI, a significant increasing trend was observed for Candida and Enterococcus.

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Lafora disease is a severe form of progressive myoclonic epilepsy with autosomal recessive inheritance diagnosed by inclusion body in biopsy. A 26-year-old woman was admitted due to complaints of frequent twitches and fainting. The 0.

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Background/aim: The evolving understanding of essential tremors (ET) has led to a new definition of neurodegenerative disease, pointing to diffuse brain network involvement with a wide spectrum of associated motor and nonmotor symptoms. Considering the fact that white matter should also be affected by the nature of the disease, our study aimed to evaluate the integrity of white matter and its clinical correlations in ET patients.

Materials And Methods: Approximately 40 patients diagnosed with ET and 40 age-and sex-matched control subjects (ranging between 18–80 years old) were included in the study.

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Background: Essential tremor (ET) is disease with both motor and non-motor features. Notable among the non-motor features is cognitive impairment. While this impairment has been attributed to cortico-thalamo-cerebellar pathway pathology, it is likely that a more complicated involvement of brain structures underlies cognitive function in ET.

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Essential tremor (ET) is the most common movement disorder which has both motor and non-motor findings such as neuropsychiatic symptoms. Alexithymia is defined as inability to identify and describe emotions experienced by one's self or others. In our study, we aimed to evaluate the neurocognitive and brain micro-structural correlates of alexithymia in ET.

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Performance of pneumonia severity index and CURB-65 in predicting 30-day mortality in patients with COVID-19.

Int J Infect Dis

September 2020

Department of Rheumatology, Gaziosmanpasa Research and Training Hospital, University of Health Sciences, Istanbul, Turkey. Electronic address:

Article Synopsis
  • The study aimed to evaluate how well CURB-65 and the pneumonia severity index (PSI) predict 30-day mortality in COVID-19 patients, along with identifying other mortality factors.
  • A retrospective analysis of 681 confirmed COVID-19 patients revealed that higher CRP levels correlated with increased mortality risk, and PSI outperformed CURB-65 in predicting mortality rates.
  • Ultimately, the research concluded that PSI is a more effective predictor of mortality than CURB-65, and incorporating CRP levels into PSI predictions did not enhance accuracy.
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Background: Defining the optimal therapeutic approach in patients with chronic obstructive pulmonary disease (COPD) bronchiectasis overlap (CBO) is challenging. The presence of emphysema suggests that COPD is the primary problem and it impacts therapeutic decision making.

Research Design And Methods: We hypothesized that the AreaFE% performance will be reliable in diagnosing the presence of emphysema such that serial CT scanning may not be needed.

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Neuroimaging depression and anxiety in essential tremor: A diffusion tensor imaging study.

Clin Imaging

March 2020

Department of Neurology, Yale School of Medicine, Yale University, New Haven, CT, USA; Department of Chronic Disease Epidemiology, Yale School of Public Health, Yale University, New Haven, CT, USA; Center for Neuroepidemiology and Clinical Neurological Research, Yale School of Medicine, Yale University, New Haven, CT, USA.

Objective: Patients with essential tremor (ET) may exhibit non-motor features, including those that are neuropsychiatric. Depression and anxiety are the most common among these. This study aims to investigate the possible relationship between microstructural brain changes and symptoms of depression and anxiety in ET.

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