A Comprehensive Evaluation of Serum Iron Status Indicators in Patients with Age-Related Macular Degeneration.

Objectives: Iron is recognized as a significant contributor to oxidative damage, and its levels tend to rise with age, potentially worsening age-related diseases. The aim of this study was to investigate the role of serum iron metabolism markers in the pathogenesis of age-related macular degeneration (AMD).

Methods: The files of all AMD patients in Kocaeli University School of Medicine between January 2017 and March 2020 were reviewed retrospectively.

Methodological and TNM Focus-Based Comparison of EGFR Mutation Status in Non-Small-Cell Lung Carcinomas.

Background: Epidermal growth factor receptor (EGFR) mutations in non-small-cell lung carcinomas (NSCLC) are a frequent class of driver mutations, and tyrosine kinase inhibitor (TKI) therapy provides considerable clinical benefits. Using the most effective and also easiest method for EGFR analysis is cost-effective and time-saving. In this study, we aimed to determine which method could be more effective by comparing the incidences of EGFR mutations in cytological and histological samples which were obtained by different methods also, whether there was a difference in the incidences of EGFR mutations between the primary foci, mediastinal lymph nodes, and distant metastatic foci.

The Effect on Constipation of Abdominal Massage Applied to the Elderly in the Nursing Home: A Randomized Controlled Experimental Study.

The aim of this study was to evaluate how abdominal massage affects the constipation of the elderly in the nursing home. This randomized controlled experimental study was conducted with an intervention group ( n = 30) and a control group ( n = 31) in the nursing home of a government institution. A 15-minute abdominal massage was applied to the intervention group once a day, 5 days a week for 1 month.

The effect of air pollution quality on lung cancer rates in middle-income and high-income countries: a panel data analysis approach.

Background: Air pollution is one of the biggest problems in societies today. The intensity of indoor and outdoor air pollutants and the urbanization rate can cause or trigger many different diseases, especially lung cancer. In this context, this study's aim is to reveal the effects of the indoor and outdoor air pollutants, and urbanization rate on the lung cancer cases.

What Factors Influence In-Hospital Mortality Following Aseptic Revision Total Hip Arthroplasty? A Single-Center Analysis of 13,203 Patients.

Background: Revision total hip arthroplasty (rTHA) is associated with an extended surgical period, an increased hospitalization period, expanded blood loss, and high mortality rates. The purpose of the present study was to assess the risk factors that contribute to in-hospital mortality following aseptic rTHA.

Methods: We performed a retrospective examination of the medical records of all patients who underwent elective rTHA surgery at our tertiary referral arthroplasty center between March 1996 and March 2019.

Clinical and Demographic Characteristics of Treatment Requiring Retinopathy of Prematurity in Big Premature Infants in Turkiye: Report No. 1 (BIG-ROP Study).

Introduction: The aim of the study was to analyse the clinical and demographic features of infants with gestational age (GA) of 32-37 weeks and birth weight (BW) of >1,500 g who developed treatment requiring retinopathy of prematurity (ROP).

Methods: Data on the infants with a GA of 32-37 weeks and BW >1,500 g who developed treatment requiring ROP (TR-ROP) were collected retrospectively from the 33 ROP centres in Turkiye. GA, BW, type of hospital, neonatal intensive care units (NICUs) level, presence of an ophthalmologist and neonatologist in the same hospital, length of stay in NICU, duration of oxygen therapy, comorbidities, type of ROP, and timing for TR-ROP development were analysed.

Psychological Balances in the Digital World: Dynamic Relationships Among Social Media Addiction, Depression, Anxiety, Academic Self-Efficacy, General Belongingness, and Life Satisfaction.

In the present era, the rapidly growing social media trends of the digital age have the potential to affect the psychological well-being of individuals. In this context, understanding how Social Media Addiction (SMA) interacts with various factors is important to understanding its potential impact on individuals' psychosocial health. In particular, the prevalence of SMA and its strong relationship with important variables such as anxiety, depression, stress, academic self-efficacy, general belongingness, and life satisfaction have received considerable attention from researchers and the society.

A large vertebral artery fenestration involving the distal segments associated with bilateral duplication of the superior cerebellar artery: a case report.

Purpose: The aim of our study is to report a case of a large fenestrated vertebral artery (FVA) and bilateral duplication of the superior cerebellar artery (SCA) incidentally diagnosed using Computed Tomography Angiography (CTA) and Digital Subtraction Angiography (DSA).

Case Presentation: A 63-year-old female patient presenting to the neurology clinic with complaints of dizziness and balance disorder. CTA and DSA revealed a large FVA involving the V3 and V4 segments.

Comparison of hand dexterity and hand laterality task in duchenne muscular dystrophy patients with typically developing peers.

Background: Hand dexterity is important with Duchenne muscular dystrophy (DMD).

Objective: The aim of this study was to compare hand dexterity and hand laterality task assessments in patients with DMD with typically-developing peers.

Methods: The study included 25 DMD with a mean age of 10.

How successful is the CatBoost classifier in diagnosing different dental anomalies in patients via sella turcica and vertebral morphologic alteration?

Background: To investigate how successfully the classification of patients with and without dental anomalies was achieved through four experiments involving different dental anomalies.

Methods: Lateral cephalometric radiographs (LCRs) from 526 individuals aged between 14 and 22 years were included. Four experiments involving different dental anomalies were created.

In silico analysis of polyphenols modulate bovine PPARγ to increase milk fat synthesis in dairy cattle via the MAPK signaling pathways.

This study investigates the potential phytochemicals that modulate bovine peroxisome proliferator-activated receptor gamma (PPARγ) and the mitogen-activated protein kinase (MAPK) pathways to enhance milk fat production in dairy animals. Bovine PPARγ, a key member of the nuclear hormone receptor superfamily, plays a vital role in regulating metabolic, cellular differentiation, apoptosis, and anti-inflammatory responses in livestock, while the MAPK pathway is contributory in cellular processes that impact milk fat synthesis. This approach involved an all-inclusive molecular docking analysis of 10,000 polyphenols to identify potential PPARγ ligands.

Internalized stigma and traumatizing effects of psychiatric hospitalization in adolescents: Is there any difference between being hospitalized in adult or adolescent inpatient psychiatric services?

Objective: Psychiatric hospitalization serves as a critical treatment modality. However, hospitalization may pose risks of traumatization or stigma. This study primarily examined the internalized stigma and traumatizing effects of psychiatric hospitalization on adolescents.

Vidian Canal in Chiari Type I Malformation: A Computed Tomography Study.

Objective: To evaluate the position and dimension of the Vidian canal (VC) in Chiari type I malformation (CIM).

Materials And Methods: Radiologic views of 49 CIM (mean age: 23.58±15.

Effects of socio-demographical characteristics of high school students on smartphone addiction and depression.

This study was conducted to determine the smartphone addiction and severity of depressive symptoms of high school students. In this descriptive cross-sectional and correlational study, the sample consisted of 1744 high school students. In the study, data were collected using a Descriptive Questionnaire, the Smartphone Addiction Scale-Short Form, and the Depression Scale for Children.

Evaluation of Cyclic Fatigue Resistance of Novel Replica-Like Instruments in Static Test Model.

Introduction: The aim of our study is to comparatively analyze the canal cyclic fatigue resistance of widely used rotary file systems, including EndoArt Touch Gold (ETG), Perfect MTF Plus Gold (PPG), Fanta V-Taper Gold (FVG), and ProTaper Next (PTN).

Methods: Stainless steel canals with a 60° angle and a 3-mm curvature radius were specially prepared. The canals were shaped with each rotary file system and tested for resistance using a cyclic fatigue testing apparatus.

Comparative Transcriptomic Analyses of Peripheral Blood Mononuclear Cells of COVID-19 Patients without Pneumonia and with Severe Pneumonia in the First Year of Follow-Up.

The multisystemic effects of COVID-19 may continue for a longer time period following the acute phase, depending on the severity of the disease. However, long-term systemic transcriptomic changes associated with COVID-19 disease and the impact of disease severity are not fully understood. We aimed to investigate the impact of COVID-19 and its severity on transcriptomic alterations in peripheral blood mononuclear cells (PBMCs) following 1 year of the disease.

Validity and reliability of the Six-Minute Pegboard Ring Test for assessing functional capacity and upper limb function in persons with multiple sclerosis.

Background: The timed walk test is essential for assessing the functional capacity of persons with multiple sclerosis (MS). When a decline in ambulation ability and loss of function in the later stages of MS is observed, it is imperative to utilize alternative methods for measuring functional capacity.

Objective: To investigate the validity and reliability of the Six-Minute Pegboard Ring Test (6PBRT) in persons with MS.

First diatom-based assessment of Lower Hari Rud River (a transboundary system) in Afghanistan.

It is essential to determine the dominant/indicator species and their ecological preferences to develop a comprehensive bioassessment strategy for rivers. The objective of this work was to provide dependable ecological evaluation techniques for ecosystems that experience significant human-induced disruptions, with the Hari Rud River (a transboundary water resource) serving as a case study during the May (wet) and July (dry) periods of 2023. Canonical correspondence analysis revealed that electrical conductivity (EC), dissolved oxygen, ortho-phosphate (P ), and nitrate (N ) had substantial impacts on the spatial distribution of diatom species in the basin.

Relationship between pain activity patterns, and physical and psychological aspects and sleep quality in women with migraine.

Migraine can cause different pain activity patterns. This cross-sectional study examines the relationship between pain activity patterns and physical and psychological aspects and sleep quality in women with migraine. Women diagnosed with migraine ( = 129) were reached through social media and announcements.