1,939 results match your criteria: "Gazi University Faculty of Medicine.[Affiliation]"

Report from the child neurology education and training workshop at the International Child Neurology Congress 2024: Expert'saddressing the training gap.

Eur J Paediatr Neurol

November 2024

Division of Epilepsy and Clinical Neurophysiology, Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA; University Teaching Hospitals-Children's Hospital, Lusaka, Zambia. Electronic address:

This report summarizes the key findings of a workshop undertaken at the International Child Neurology Congress in 2024 by child neurologists with expertise in training education and invested colleagues. The workshop aimed to explore global issues which have impact on access to child neurology training. The major findings supported a great need for more training programs globally, that consensus is needed for the minimum standards of training, and that training programs can be strengthened via global health partnerships especially with collaborations from regions with more available resources.

View Article and Find Full Text PDF

Totally Robotic Donor Nephrectomy for Living Donors Using a Novel Technique: Single-Center Experience.

Exp Clin Transplant

September 2024

>From the Department of General Surgery, Gazi University Faculty of Medicine; and the Transplantation Center, Gazi University, Ankara, Türkiye.

Article Synopsis
  • Robot-assisted laparoscopic donor nephrectomy for living kidney transplants has become widely used since its introduction in 2000, prompting a study of its implementation and a modified surgical technique from 2015 to 2023.
  • The study analyzed data from 55 donors, noting demographics like age and body mass index, with most procedures performed on the left kidney and no instances of graft loss among recipients.
  • While the new technique shows promise as a safe and effective option, its high cost is a significant concern that calls for future efforts to reduce expenses through innovative methods.
View Article and Find Full Text PDF
Article Synopsis
  • The study focuses on understanding primary hypertension (HT) in adolescents, highlighting its rising prevalence and potential impact on neurocognitive function and academic performance.
  • It analyzed the clinical characteristics and academic grades of 83 high school students with primary HT, finding that higher body mass index and health complications were linked to lower grades in key subjects like Mathematics and Turkish Language.
  • Results suggest that HT negatively affects academic skills and emphasizes the need for comprehensive management strategies to control hypertension among adolescents.
View Article and Find Full Text PDF
Article Synopsis
  • This study investigates the link between sepsis-induced acute kidney injury (AKI) and worse outcomes in patients in the intensive care unit (ICU), focusing on identifying risk factors for new-onset AKI among septic patients who initially had no kidney issues.
  • Conducted at Gazi University Hospital, the research involved analyzing data from septic patients aged 18 and older, looking at demographics and clinical factors to determine predictors of AKI development and mortality rates.
  • Results showed a significant incidence of new-onset AKI (36%), particularly linked to factors like invasive mechanical ventilation, new-onset shock, and higher APACHE-II scores, all of which correlated with longer ICU stays and increased mortality risk.*
View Article and Find Full Text PDF

Introduction: Although motor imagery (MI) has been reported to increase motor cortical excitability, its effect on central motor conduction time (CMCT), a widely used neurophysiological diagnostic method, has not been investigated. In this study, we sought to determine the effect of MI on CMCT.

Methods: In this cross-sectional study, 21 healthy volunteers (11 females, 10 males) aged 24 to 67 years (mean age: 38.

View Article and Find Full Text PDF

The vein of Galen arteriovenous malformation is a rare abnormality of the fetal cerebral vascular system. It is caused by the persistence of a cerebral arteriovenous fistula of the median prosencephalic vein. Due to the high mortality rate of the surgical option in its treatment, the approach with embolization and radiosurgery combinations continues to be popular.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the prognostic factors for C3 glomerulopathy (C3G), focusing on the total chronicity score (TCS) derived from a new histological index (C3G-HI).
  • 74 patients from 20 medical centers were analyzed to determine factors affecting kidney health outcomes, with a particular emphasis on hemoglobin levels and their correlation with patient survival and kidney function.
  • Results indicated that low hemoglobin levels were linked to worse outcomes in C3G patients, and a TCS of 4 or higher correlated with significantly lower kidney survival rates over three years.
View Article and Find Full Text PDF

Background: Craniopharyngiomas are rare tumors that originate from the squamous epithelium in Rathke's sac residues. There is a limited body of literature on the effect of using intraoperative magnetic resonance imaging (IO-MRI) in resection of craniopharyngiomas via endoscopic endonasal surgery (EES). The present study aims to assess the outcomes of EES for resection of craniopharyngiomas using IO-MRI.

View Article and Find Full Text PDF
Article Synopsis
  • Pregnancy can significantly impact heart health, potentially leading to serious complications in women with existing cardiovascular issues.
  • It's crucial to assess a pregnant woman's heart health by reviewing her medical history, symptoms, and overall physical condition to prevent complications for both the mother and fetus.
  • The case series highlights the experiences of four patients facing severe heart conditions during pregnancy, showcasing the need for careful monitoring and evaluation.
View Article and Find Full Text PDF
Article Synopsis
  • Phenylketonuria (PKU) is a genetic condition where too much phenylalanine (Phe) builds up in the body, which can be harmful to the brain.
  • The APHENITY study tested a new medicine called synthetic sepiapterin to see if it could safely lower Phe levels in patients with PKU.
  • The study involved 187 participants from 34 locations around the world and lasted from September 2021 to April 2023, with results showing how effective the treatment was over a six-week period.
View Article and Find Full Text PDF

Background: Juvenile idiopathic arthritis (JIA) is a common chronic rheumatic disease in children, requiring careful management to reduce both short- and long-term morbidity. In this study, our objective was to assess the clinical features of patients diagnosed with JIA who received intra-articular corticosteroid injections (IACI).

Methods: In this retrospective study, we evaluated the clinical and laboratory characteristics of 225 JIA patients monitored from January 2012 to October 2023 at a tertiary care center.

View Article and Find Full Text PDF
Article Synopsis
  • Congenital diarrhea can be tough to diagnose, especially when standard tests don't give clear results.
  • A female infant presented symptoms of osteopetrosis along with unexplained diarrhea, leading to genetic testing that uncovered a significant deletion on chromosome 16p13.3.
  • This case highlights the need to investigate genetic factors, like 16p13.3 deletions, when diagnosing conditions that seem to involve multiple symptoms.
View Article and Find Full Text PDF

Objective: General surgery is a fundamental medical discipline that requires extensive training to develop competent surgeons. This study examines the impact of the number of residents on surgical training quality in a general surgery clinic and evaluates the usability of the Surgery-to-Resident Ratio (SRR) in determining the ideal number of residents.

Design: Retrospective analysis.

View Article and Find Full Text PDF
Article Synopsis
  • This study looked at how doctors treat babies with a serious condition called long-gap esophageal atresia (LGEA) using special methods.
  • They checked the medical records of 10 patients and found that different surgical techniques were used, like the Foker and Gazi methods, to help the babies eat normally.
  • It was important for these surgeries to be done by skilled surgeons in special hospitals to get the best results for the babies.
View Article and Find Full Text PDF
Article Synopsis
  • Ischemia-reperfusion (I/R) injury can cause severe testicular damage and infertility, prompting research on fasudil as a potential protective treatment.
  • The study involved 30 male Long-Evans rats divided into groups to compare the effects of fasudil treatment before and after I/R injury against control and untreated injured groups.
  • Results showed that fasudil significantly reduces indicators of tissue damage and inflammation, especially when given before detorsion, suggesting it offers protection against I/R injury in testicular tissue.
View Article and Find Full Text PDF

This is the first study to examine the role of monocyte distribution width (MDW) in predicting sepsis after cardiovascular surgery. This study included 43 consecutive patients who had undergone cardiovascular surgery between July 2021 and July 2022. All patients were examined at the following three time points (TPs): preoperative period (TP1), postoperative at 24 h (TP2), and discharge (TP3).

View Article and Find Full Text PDF

Total neoadjuvant therapy (TNT) has emerged as a promising approach for managing locally advanced rectal cancer (LARC), aiming to enhance resectability, increase pathological complete response (pCR), improve treatment compliance, survival, and sphincter preservation. This study compares the clinical outcomes of TNT, with either induction or consolidation chemotherapy, to those of the standard chemoradiotherapy (CRT). In this retrospective multi-institutional study, patients with stage II-III LARC who underwent CRT or TNT from seven oncology centers between 2021 and 2024 were retrospectively analyzed.

View Article and Find Full Text PDF

Lysosomal storage disorders (LSD) are a group of inherited inborn metabolism errors that are characterized by a deficiency in the lysosomal enzyme. In patients with suspected lipid storage disorders, confirmation of the diagnosis relies predominantly on the measurement of specific enzymatic activities and molecular genetic studies. New approaches to the measurement of lysosphingolipids have been developed that may serve as a rapid first-tier screening tests for the evaluation of lysosomal storage disorders.

View Article and Find Full Text PDF

Objective: This study aimed to demonstrate whether ozone has cardioprotective effects on the myocardial ischemia-reperfusion injury (IRI) in rats with streptozotocin(STZ)-induced diabetes.

Methods: A total of 38 male Wistar Albino rats were divided into five groups as follows: control group (group C,=6), diabetic group (group D,=6), diabetic ozone group (group DO,n=6), diabetic-ischemia/reperfusion (group DIR,=6), diabetic-ischemia/reperfusion-ozone (group DIRO,=6). Six rats died during this period and two died because of surgical complications.

View Article and Find Full Text PDF

Objectives: We aimed to report the characteristics of pediatric IgG4-related disease (IgG4-RD) through a multicentre registry, to assess disease clusters, and to evaluate the performances of the 2019 American College of Rheumatology and European League Against Rheumatism (ACR/EULAR) classification criteria and the 2020 revised comprehensive diagnostic (RCD) criteria in this cohort.

Methods: Data of IgG4-RD patients in 13 pediatric rheumatology centers were recorded to a web-based registration system. The diagnosis of IgG4-RD was made according to the 2011 comprehensive diagnostic criteria.

View Article and Find Full Text PDF