The impact of "nurse-led education" vs. "nurse-led education plus peer support" on patients' decision for peritoneal dialysis treatment in chronic kidney disease patients.

Introduction: End-stage kidney disease patients face a critical decision regarding kidney replacement therapy options, which include kidney transplantation, hemodialysis, or peritoneal dialysis (PD). This study aims to evaluate the impact of nurse-led education (NE) alone vs. NE combined with peer support on the patients' decision over PD treatment in chronic kidney disease patients.

Outcome of Soft Tissue Popliteal Sarcomas: 15 Years of Experience.

Background: Soft-tissue sarcoma involving the popliteal fossa remains challenging because it is difficult to achieve wide margins with limb salvage in this location. Adjuvant therapy is frequently necessary, and limb function can be adversely affected. We reviewed our experience with these tumors.

Comparative Analysis of Whole-Body Diffusion-Weighted Imaging and PET/CT in Metastasis Detection: A Prospective Study.

Introduction Tumor staging is essential for determining treatment strategies and predicting prognosis in cancer patients. Accurate imaging techniques are critical for staging, metastasis screening, treatment response assessment, and recurrence detection. Objective In this prospective study, we aimed to compare the sensitivity of whole-body diffusion-weighted imaging (WB-DWI) with positron emission tomography/computed tomography (PET/CT) in detecting metastases.

Comparison of rigid and elastic registration methods in software-based targeted prostate biopsy: a multicenter cohort study.

Background/aim: This study aims to compare the success rates of rigid registration (RR) and elastic registration (ER) systems in diagnosing all cancers and clinically significant prostate cancer (csPC) in software-based targeted prostate biopsies (TPBs) by performing matching analysis.

Materials And Methods: The data of 2061 patients from six centers where software-based TPB is performed were used. All cancer and csPC detection rates of the RR and ER systems were compared following Mahalanobis distance matching with the propensity score caliper method.

Evaluation of single-layer versus double-layer suturing of low transverse uterine incisions in cesarean section and follow-up of scars by ultrasound: a prospective randomized controlled study.

Background/aim: Cesarean section (CS) is a widely performed operation worldwide but data about uterine closure are lacking. We aimed to evaluate scar niches and compare single-layer and double-layer uterine closure at 6 months following CS.

Materials And Methods: This prospective randomized trial assessed 56 women undergoing single- or double-layer uterine closure.

Association between serum albumin levels at admission and clinical outcomes in pediatric intensive care units: a multi-center study.

Background: Albumin, a vital component in regulating human blood oncotic pressure, plays an important role in the prediction of prognosis in pediatric patients.Previous research identified significant differences in serum albumin levels of healthy and critically ill children.

Methods: The present study aims to investigate the correlation between albumin levels measured during pediatric intensive care unit(PICU) admission and clinical outcomes.

Effect of cementation technique and cement type on the amount of excess cement in implant-supported cement-retained crown restorations: An in vitro study.

Statement Of Problem: Excess cement in implant-supported restorations can lead to peri-implant diseases, and its removal remains a clinical challenge. The optimum method of minimizing excess cement is unclear.

Purpose: The purpose of this in vitro study was to compare 3 cementation techniques and 3 cement types and measure excess cement.

Effects of Globularia cordifolia on colon cancer cells: antioxidant activity, inflammatory cytokine analysis and molecular docking studies.

Background: The present study aimed to comprehensively evaluate the anticancer, anti-inflammatory, and antioxidant properties of Globularia cordifolia L.

Samples: The plant material was collected and extracted using the maceration method. Antioxidant activities were assessed through DPPH (i.

Quinazoline derivatives as novel bacterial sphingomyelinase enzyme inhibitors.

Bacillus cereus sphingomyelinase C (B. cereus SMase), which plays a crucial role in bacterial virulence, has emerged as a new therapeutic target for treating opportunistic infections caused by this pathogen. It also shares catalytic domain similarity with human neutral sphingomyelinase 2 (nSMase2), which is implicated in Alzheimer's disease.

Evaluation of the Effect of Chitosan-Based Irrigation Solutions on the Bond Strength of Mineral Trioxide Aggregate to Bulk-Fill Composite.

Bond strength between repair and restorative materials is crucial for endodontic success. This study assessed the effects of the following final irrigation solutions on the bond strength of mineral trioxide aggregate (MTA) to a bulk-fill composite: (1) 17% Ethylenediamine tetraacetic acid (EDTA); (2) 2% Chlorhexidine (CHX); (3) 0.2% chitosan; (4) 0.

Analysis of ROMO1 Expression Levels and Its Oncogenic Role in Gastrointestinal Tract Cancers.

Gastrointestinal tract cancers account for approximately one-third of cancer-related deaths. Early diagnosis and effective treatment are the most important ways to prevent cancer-related morbidity and mortality. ROMO1 has been shown to play an important role in many types of cancer.

Development of immediate release tablet formulations of lornoxicam with hot melt extrusion-based three-dimensional printing technology.

Introduction: This study aims to develop immediate release tablet formulations of lornoxicam (LRX) using hot melt extrusion (HME)-based fused deposition modeling (FDM) focusing on the adjustment of drug release by arranging infill densities and evaluating microcrystalline cellulose II (MCC II) as a disintegrating agent for HME-FDM purposes. LRX is a poorly soluble drug that exhibits pH-dependent solubility with a high thermal degradation temperature. These characteristics make it an ideal model drug for the HME-based FDM technique.

Enhancing multiple sclerosis diagnosis: A comparative study of electroencephalogram signal processing and entropy methods.

As one of the most common neurodegenerative diseases, Multiple sclerosis (MS) is a chronic immune-driven disorder that affects the central nervous system (CNS). Due to the variety of symptoms, accurately diagnosing MS demands rigorous attention to differential diagnosis, as various disorders can closely mimic its clinical and paraclinical features. Although MR imaging techniques are gold standards in diagnosing MS, the feasibility of advanced Electroencephalogram (EEG) signal processing methods is discussed in this study to detect patients with MS disorder.

Effects of dynamic elastomeric fabric orthoses in children with cerebral palsy: A single-blind randomized controlled trial.

Background: The dynamic elastomeric fabric orthoses (DEFOs) are made of neoprene material, providing the right biomechanical alignment and afferent input in the trunk, pelvis, and extremities, potentially allowing individuals to actively participate in daily life.

Objective: The aim of this study was to investigate the effects of DEFOs applied to the lower trunk and pelvis, on balance, gait parameters, and pelvic symmetry in children with cerebral palsy (CP).

Study Design: An evaluator-blinded randomized controlled trial.

PlutoNet: An efficient polyp segmentation network with modified partial decoder and decoder consistency training.

Deep learning models are used to minimize the number of polyps that goes unnoticed by the experts and to accurately segment the detected polyps during interventions. Although state-of-the-art models are proposed, it remains a challenge to define representations that are able to generalize well and that mediate between capturing low-level features and higher-level semantic details without being redundant. Another challenge with these models is that they are computation and memory intensive, which can pose a problem with real-time applications.

Frequency of severe infections in rheumatic disease patients receiving bDMARDs post-kidney transplantation: a multicenter study.

Objectives: To evaluate the incidence and characteristics of severe infections in rheumatic patients receiving biologic disease-modifying anti-rheumatic drugs (bDMARDs) after kidney transplantation.

Methods: This multicenter, retrospective study included 38 patients who had undergone kidney transplantation and received bDMARDs for rheumatic diseases. Demographic, clinical, and treatment data were collected.

Long-term Complications and Testicular Adrenal Rest Tumors in Congenital Adrenal Hyperplasia.

Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency accounts for approximately 95% of all CAH cases and is one of the most common inborn errors of metabolism. While glucocorticoid therapy has significantly improved patient outcomes, the focus has shifted towards managing the long-term effects. Numerous adverse outcomes have been associated with CAH, including those resulting from supraphysiological doses of glucocorticoid and mineralocorticoid replacement, excessive adrenal androgen secretion, and elevated levels of steroid precursors and adrenocorticotropic hormone.

Can ChatGPT generate surgical multiple-choice questions comparable to those written by a surgeon?

Background: This study aimed to determine whether surgical multiple-choice questions generated by ChatGPT are comparable to those written by human experts (surgeons).

Methods: The study was conducted at a medical school and involved 112 fourth-year medical students. Based on five learning objectives in general surgery (colorectal, gastric, trauma, breast, thyroid), ChatGPT and surgeons generated five multiple-choice questions.

Prognostic value of HER2 2 + expression in patients with TNBC receiving adjuvant capecitabine.

Background: In triple-negative breast cancer (TNBC) patients receiving adjuvant capecitabine, the impact of HER2 expression on survival outcomes is unclear.

Methods:  Between June 2017 and December 2023, 112 patients with TNBC who received adjuvant capecitabine due to residual masses after neoadjuvant chemotherapy (NACT) in three hospitals were identified. HER2 is analyzed through immunohistochemistry (IHC) and/or in situ hybridization in the core biopsy and/or post-surgical histopathologies.

Comparison of IL-1 Receptor Antagonist and Dexamethasone in Noise-Induced Hearing Loss: Animal Model.

Objective: This study aimed to attenuate cochlear inflammation following noise-induced hearing loss by targeting IL-1. We evaluated the effectiveness of IL-1 inhibition through auditory and histological assessments in an animal model.

Study Design: Experimental animal study.

The impact of cold application on pain and comfort during the process of diabetic foot care.

Background And Aim: Given the significance of pain management in the context of diabetic foot ulcer (DFU) care, particularly in terms of ensuring patient adherence to treatment regimens, this study was undertaken to ascertain the impact of cold washing on pain and comfort levels during diabetic foot care.

Methods: A single-blind randomized controlled trial was conducted in the chronic wound care clinic of a teaching and research hospital in the southeastern region of Turkey. The sample consisted of 68 patients, with 34 assigned to the cold application group and 34 assigned to the control group.

Assessment of atmospheric volatile organic compounds at two crude oil production plants in Southeastern Türkiye.

Ambient Volatile Organic Compounds (VOCs) were investigated to determine their characteristics, Ozone Formation Potentials (OFPs), and health risks in two crude oil production plants (Nusaybin and Egil plants) in southeastern Türkiye. Benzene, toluene, ethylbenzene, m + p xylene, o xylene, and 1,3,5-trimethylbenzene were measured at eight passive sampling points in each plant. Samples were analyzed using gas chromatography coupled with a flame ionization detector and a thermal desorption.