The anatomy and histology of the midgut and Malpighian tubules of Copris felschei Reitter, 1892 (Coleoptera: Scarabaeidae).

Copris are part of the Scarabaeidae family of Coleoptera. Copris are dung beetles or coprophagous beetles. These insects are called tunnelers because they excavate channels in the substrate.

Synthesis of fluorescent dicyanomethylenevinyl-1,3-dicoumarin compounds with donor-acceptor-π-donor (D-A-π-D) system and investigation of their photophysical, NLO, and chemosensor properties: Part 1.

Coumarin compounds have heterocyclic core with different properties such as high quantum yields, broad Stokes shifts, and superior photophysical and biological activity. It is known that fluorescence properties increase with increased intramolecular charge transfer in systems where electron-withdrawing or donor groups are attached to different positions of the coumarin compound. When these compounds interact with analytes in the environment, the analytes in the environment can be detected by quenching or increasing fluorescence.

Antioxidant, Antimicrobial, Anticancer, and Molecular Docking Insights into Pancratium maritimum Seeds and Flowers: A Phytochemical Approach.

This study investigates the antioxidant, antimicrobial, and anticancer properties of Pancratium maritimum L. in Sp. Pl.

The imposter phenomenon in psychiatrists: relationships among compassion fatigue, burnout, and maladaptive perfectionism.

Background: The imposter phenomenon is the unwillingness to acknowledge one's triumphs, which is common among doctors. Research on the imposter phenomenon among mental health professionals is limited, and the relationship between imposter phenomenon, burnout, and compassion fatigue has not been studied. The current study intended to test a hypothesized model of the specific impact paths among burnout, compassion fatigue, maladaptive perfectionism, and imposter phenomenon among mental health professionals.

Chronic disease risk factors among hospital employees: A cross-sectional study in Türkiye.

Introduction: Chronic diseases have become a significant public health problem with the prolongation of human life. There are four main behavioral risk factors for mortality. This study evaluated the significant risk factors for chronic diseases in university hospital employees.

Trends in prescribing montelukast in patients with asthma in real-life: Results from the Turkish adult asthma registry.

Montelukast, a leukotriene receptor antagonist (LTRA) approved for the treatment of asthma and allergic rhinitis, is widely used, though real-world data on its application in asthma management remain limited. This registry-based study evaluated the use of montelukast in adult asthma patients, examining demographic and disease characteristics, asthma control status, asthma phenotypes, presence of atopy, and treatment regimens. Among 2053 patients analyzed, 61.

Effect of Plant-Based Diets on Rheumatoid Arthritis: A Systematic Review.

Context: Rheumatoid arthritis (RA) is an autoimmune disease that leads to chronic inflammation and joint damage. Various plant-based diets are thought to have effects on RA symptoms and disease activity.

Objective: Relevant literature on the effect of different types of plant-based diets on RA was reviewed.

Upper Extremity Exercise Capacity and Muscle Oxygenation in Patients With Primary Ciliary Dyskinesia.

Background And Objectives: Patients with primary ciliary dyskinesia (PCD) have a reduction in exercise capacity from the early stages. Although there are studies investigating these patients' lower extremity exercise capacity using various methodologies, there needs to be more research on the functional exercise capacity of the upper extremities. This study aimed to compare pulmonary function, upper extremity functional exercise capacity, muscle oxygenation, muscle strength, and physical activity level in children with PCD and controls.

The relationship between temperament with nutritional status and anthropometric measurements in adult individuals.

Interest in studies examining the effect of temperament types on nutrition has recently increased. The aim of this study was to evaluate the relationship between nine types of temperament, anthropometric measurements, and nutrition in adults. This study was conducted on 1317 individuals aged between 18 and 55 years.

Arthroscopic-Assisted Lower Trapezius Tendon Transfer With Fascia Lata Autograft for Irreparable Posterior-Superior Rotator Cuff Tears.

Lower trapezius tendon transfer is a surgical procedure that has become increasingly popular in recent years. The biggest advantage of this method is that the pulling direction of the lower trapezius is the same as that of the infraspinatus. Thus, the transferred lower trapezius tendon can biomechanically mimic the functions of the posterior-superior rotator cuff.

Sulfur dioxide (SO) donors, a new gasotransmitter, improve erectile dysfunction after castration in a rat model.

Background: Androgen deprivation is associated with erectile dysfunction (ED). In different animal models, sulfur dioxide (SO) donors NaSO and NaHSO reduced oxidative stress, fibrosis, and inflammation which contribute to the pathogenesis of androgen deprivation-induced ED, however the effect of SO donors on ED in castrated rats were not known.

Objective: To investigate the therapeutic effect of SO donors, NaSO/NaHSO, on ED in castrated rat model.

Anterior and Posterior Ocular Changes in Patients with Active and Inactive Ankylosing Spondylitis.

BACKGROUND The 6-item Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) is a method for evaluating disease activity in ankylosing spondylitis (AS). This study included 78 patients with active and inactive AS and aimed to evaluate anterior and posterior segment ocular changes. MATERIAL AND METHODS Seventy-eight patients and 70 control subjects were enrolled in this study.

Assessing the bond strength of short fiber composites to dentin using various air abrasion particles.

Purpose: This study investigated the bond strength between short fiber-reinforced resin composite (SFC) and dentin following air abrasion with various types of abrasive particles.

Methods: A total of 120 human molars were prepared for a shear bond strength (SBS) test of the resin composite. The teeth were divided into 12 groups (n = 10/group) based on the air abrasion particle used.

Pomalidomide, Bortezomib, and Dexamethasone Versus Bortezomib and Dexamethasone in Relapsed or Refractory Multiple Myeloma: Final Survival and Subgroup Analyses From the OPTIMISMM Trial.

Introduction: In the OPTIMISMM trial, pomalidomide/bortezomib/dexamethasone (PVd) significantly prolonged median progression-free survival (PFS) versus bortezomib/dexamethasone (Vd) in lenalidomide-exposed relapsed and refractory multiple myeloma (RRMM). We report final overall survival (OS) and updated efficacy analyses.

Methods: Adults with RRMM who had 1-3 prior regimens, including lenalidomide (≥ 2 cycles), were assigned (1:1) to PVd or Vd.

Anthropometric Measurements and Laboratory Methods for Pregnancy: An Update Review to Evaluation of Body Composition.

Purpose Of Review: The aim of this review is to summarize and put into context the current evidence on anthropometric measurements and laboratory methods used in the evaluation of body composition in pregnancy, in the light of current studies.

Recent Findings: Protecting women's health during pregnancy, childbirth and the postnatal period is important for maternal health. Pregnancy is a critical period during which the female body undergoes significant changes to support fetal growth and development.

Dystonia caused by ANO3 variants is due to attenuated Ca influx by ORAI1.

Background: Dystonia is a common neurological hyperkinetic movement disorder that can be caused by mutations in anoctamin 3 (ANO3, TMEM16C), a phospholipid scramblase and ion channel. We previously reported patients that were heterozygous for the ANO3 variants S651N, V561L, A599D and S651N, which cause dystonia by unknown mechanisms.

Methods: We applied electrophysiology, Ca measurements and cell biological methods to analyze the molecular mechanisms that lead to aberrant intracellular Ca signals and defective activation of K channels in patients heterozygous for the ANO3 variants.

Effects of Cerium Oxide on Kidney and Liver Tissue Damage in an Experimental Myocardial Ischemia-Reperfusion Model of Distant Organ Damage.

Ischemia-reperfusion (I/R) injury is a process in which impaired perfusion is restored by restoring blood flow and tissue recirculation. Nanomedicine uses cutting-edge technologies that emerge from interdisciplinary influences. In the literature, there are very few in vivo and in vitro studies on how cerium oxide (CeO) affects systemic anti-inflammatory response and inflammation.

Effects of Manual Therapy and Home Exercise Treatment on Pain, Stress, Sleep, and Life Quality in Patients with Bruxism: A Randomized Clinical Trial.

: This study aimed to examine the effects of manual therapy (MT) and home exercise (HE) treatments on pain, sleep quality, stress level, and quality of life in patients with bruxism. : The study included 30 bruxism patients ages 18-25 years who were randomly divided into the manual therapy group (MTG) and home exercise group (HEG). Before treatment (T1), all patients were asked to fill out the Pittsburgh Sleep Quality Index (PSQI), Perceived Stress Scale (PSS), Fonseca Anamnestic Index (FAI), and Quality of Life Scale/Short Form-36 (SF-36), and additionally, the number of trigger points (NTP) and pain levels were determined.

Impact of Serum GDF-15 and IL-6 on Immunotherapy Response in Cancer: A Prospective Study.

Background: Immunotherapy has transformed cancer treatment; however, predicting treatment response remains challenging. Serum biomarkers can help identify patients who are most likely to benefit from immunotherapy.

Objective: This study evaluates the relationship between serum growth differentiation factor 15 (GDF-15) and interleukin-6 (IL-6) levels and treatment outcomes in cancer patients undergoing second-line immunotherapy.

Effect of propolis supplementation on cadmium toxicity associated with renal and hepatic dysfunction in rats.

Cadmium (Cd), one of the toxic heavy metals, is of great importance for public health due to its use in many industrial areas. Propolis is a natural product with antioxidant and anti-inflammatory properties collected from plants by honey bees. The aim of this study was to investigate the protective role of propolis against the potential toxic effects of cadmium chloride in blood, liver and kidney tissues.

Comprehensive Analysis of Elemental and Metabolite Composition in Boraginaceae Species from Türkiye.

Boraginaceae plants, including four endemic species from Türkiye, were analyzed for organic and inorganic compositions using ICP-MS and LC-MS/MS to explore their nutritional, medicinal, and ecological significance. This study examined 18 species, identifying key elements such as sodium (87,600.359-118,049.

Blood flow restriction combined with nordic hamstring exercise does not impair endothelial function but does not increase neuromuscular activation.

Background: Optimizing hamstring exercises is crucial for injury prevention and performance. This study explored the effects of blood flow restriction (BFR) during Nordic hamstring exercises (NHE) on hamstring muscle activation and vascular function.

Methods: A randomized, single-blind study included 14 healthy, physically active males (mean age: 27.

The cumulative effect of ellagic acid and carnosic acid attenuates oxidative events during diabetic wound healing: in different applications and on different days.

Background/aim: The hyperglycemic environment in diabetes disrupts normal wound-healing processes, leading to chronic wounds. This study investigated whether the combination of the phenolic compounds ellagic acid and carnosic acid shows synergistic effects on diabetic wound healing and oxidative parameters in diabetic rats.

Materials And Methods: Diabetic rats were divided into control, untreated, Carbopol 974P treated, topical treatment, and oral gavage treatment groups.