8,718 results match your criteria: "Gastritis and Peptic Ulcer Disease"
Expert Rev Anti Infect Ther
August 2024
Department of Pharmacy, Faculty of Science, National University of Singapore, 4 Science Drive 2, Singapore 117545, Singapore.
Ir J Med Sci
August 2024
Gastroenterology Unit, ASL Toscana Nord-Ovest, 'San Luca' Hospital, Lucca, Italy.
Aging (Albany NY)
August 2024
Department of Gastroenterology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, China.
PLoS One
August 2024
College of Public Health, Medical and Veterinary Sciences, James Cook University, Queensland, Australia.
Background: Helicobacter pylori (H. pylori) is frequently associated with non-cardia type gastric cancer, and it is designated as a group I carcinogen. This study aimed to systematically review and meta-analyze the evidence on the prevalence of CagA status in people with gastric disorders in the Indo-Pacific region, and to examine the association of CagA positive in the risk of gastric disorders.
View Article and Find Full Text PDFHelicobacter
August 2024
Department of Gastroenterological Endoscopy, Tokyo Medical University Hospital, Tokyo, Japan.
Nutrients
August 2024
Department of Food and Nutrition, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Phytochemicals found in fruits, vegetables, and plant-based foods have potential protective effects against various diseases, including gastric disorders. This study aimed to analyze the longitudinal association between phytochemical intake and the risk of gastritis/gastric ulcer in Korean adults. This was a prospective cohort study, a community-based cohort conducted as part of the Korean Genome and Epidemiology Study, examining the association between phytochemical intake and the risk of gastritis/gastric ulcer in Korean adults.
View Article and Find Full Text PDFInt J Biol Sci
August 2024
Center of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, China.
has been recognized not only as a causative agent of a spectrum of gastroduodenal diseases including chronic gastritis, peptic ulcer, mucosa-associated lymphoid tissue lymphoma, and gastric cancer, but also as the culprit in several extra-gastric diseases. However, the association of infection with extra-gastric diseases remains elusive, prompting a reevaluation of the role of -derived outer membrane vesicles (OMVs). Like other gram-negative bacteria, constitutively sheds biologically active OMVs for long-distance delivery of bacterial virulence factors in a concentrated and protected form, averting the need of direct bacterial contact with distant host cells to induce extra-gastric diseases associated with this gastric pathogen.
View Article and Find Full Text PDFObjective: To compare serum levels of pepsinogen I (PGI), pepsinogen II (PGII), and gastrin-17 (G-17) among patients with gastritis, gastric ulcer, and gastric cancer, and to assess the effectiveness of these biomarkers individually and in combination for screening gastric cancer.
Methods: Serum levels of PGI, PGII, and G-17 were measured using enzyme-linked immunosorbent assay (ELISA) in 50 patients with gastric cancer, 60 with chronic gastritis, and 60 with gastric ulcer from February 2020 to June 2021. The diagnostic value of these biomarkers was analyzed through sensitivity, specificity, and ROC curve assessments.
Crit Rev Microbiol
July 2024
Department of Gastroenterology, Digestive Disease Hospital, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Infection with induces chronic gastric inflammation, progressing to peptic ulcer and stomach adenocarcinoma. Macrophages function as innate immune cells and play a vital role in host immune defense against bacterial infection. However, the distinctive mechanism by which evades phagocytosis allows it to colonize the stomach and further aggravate gastric preneoplastic pathology.
View Article and Find Full Text PDFBMC Surg
July 2024
Division of Metabolic and Bariatric Surgery, Department of General Surgery, Beijing Friendship Hospital, National Clinical Research Center for Digestive Diseases, Capital Medical University, 95 Yong-an Road, Xi-Cheng District, Beijing, 100050, China.
BMC Pediatr
July 2024
Department of Pediatrics, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Background: Helicobacter pylori eradication therapy based on antimicrobial susceptibility in Vietnamese children currently get low efficiency. There are causes of treatment failure, among host genetic factors namely MDR1 C3435T and CYP2C19 affect the absorption and metabolism of proton pump inhibitors - a crucial component of eradication therapy. The study aimed to investigate the effect of MDR1 C3435T and CYP2C19 genetic polymorphisms on the cure rate.
View Article and Find Full Text PDFEgypt J Immunol
July 2024
Department of Conservative Dentistry, College of Dentistry, University of Babylon, Hilla, Iraq.
Helicobacter pylori is Gram negative bacteria, the reason for causing peptic ulcer. There is suggestion between the presence of H. pylori in oral cavity and gastritis.
View Article and Find Full Text PDFCureus
June 2024
Anesthesiology and Reanimation, Giresun University the Faculty of Medicine, Giresun, TUR.
Clin Case Rep
July 2024
Pediatric Chronic Kidney Diseases Research Center, Children's Medical Center Tehran University of Medical Sciences Tehran Iran.
Key Clinical Message: As there is no significant mutual relationship between infection and chronic kidney disease in children, its routine study is not justified and is recommended only in symptomatic cases.
Abstract: Children suffering from chronic kidney disease (CKD) often complain of indigestion but, if it is accompanied by abdominal pain, it is necessary to investigate and rule out Helicobacter pylori infection to confirm functional dyspepsia. Epidemiological studies in adults have conflicting results regarding the association between infection and CKD.
Int J Surg
July 2024
Nanjing Children's Hospital, Clinical Teaching Hospital of Medical School, Nanjing University, Nanjing, 210008, China.
Cureus
May 2024
Internal Medicine, Al Assad University Hospital, Damascus, SYR.
Gastrointestinal (GI) disorders, including gastroesophageal reflux disease (GERD), inflammatory bowel disease (IBD), gastritis/peptic ulcer disease (PUD), and celiac disease, significantly impact global health and economic stability. This review synthesizes current literature to elucidate the pathophysiology, clinical manifestations, diagnostic challenges, and management strategies of these prevalent conditions. Through a biopsychosocial lens, we examine the role of the gut microbiome in disease modulation and explore innovative therapeutic advancements, including microbiome-targeting interventions.
View Article and Find Full Text PDFInt J Mol Sci
May 2024
Dipartimento di Medicina, Chirurgia e Farmacia, University of Sassari, Clinica Medica, Viale San Pietro 8, 07100 Sassari, Italy.
Trained immunity is a concept in immunology in which innate immune cells, such as monocytes and macrophages, exhibit enhanced responsiveness and memory-like characteristics following initial contact with a pathogenic stimulus that may promote a more effective immune defense following subsequent contact with the same pathogen. , a bacterium that colonizes the stomach lining, is etiologically associated with various gastrointestinal diseases, including gastritis, peptic ulcer, gastric adenocarcinoma, MALT lymphoma, and extra gastric disorders. It has been demonstrated that repeated exposure to can induce trained immunity in the innate immune cells of the gastric mucosa, which become more responsive and better able to respond to subsequent infections.
View Article and Find Full Text PDFGastric Cancer
September 2024
Department of Family Medicine and Primary Care, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Objective: To compare the risks of gastric cancer and other gastric diseases in patients with type-2 diabetes mellitus (T2DM) exposed to sodium-glucose cotransporter 2 inhibitors (SGLT2I), dipeptidyl peptidase-4 inhibitors (DPP4I) or glucagon-like peptide-1 receptor agonists (GLP1a).
Design: This was a population-based cohort study of prospectively collected data on patients with T2DM prescribed SGLT2I, DPP4I or GLP1a between January 1st 2015 and December 31st 2020 from Hong Kong. The outcomes were new-onset gastric cancer, peptic ulcer (PU), acute gastritis, non-acute gastritis, and gastroesophageal reflux disease (GERD).
Background: Helicobacter pylori (H. pylori) can evade the host's immune response and persist for a long time on the gastric mucosa. T helper (Th) cells appear to be involved in the control of H.
View Article and Find Full Text PDFCommun Biol
May 2024
Centre for Precision Health, Edith Cowan University, Joondalup, 6027, Western, Australia.
Studies suggest links between diabetes and gastrointestinal (GI) traits; however, their underlying biological mechanisms remain unclear. Here, we comprehensively assess the genetic relationship between type 2 diabetes (T2D) and GI disorders. Our study demonstrates a significant positive global genetic correlation of T2D with peptic ulcer disease (PUD), irritable bowel syndrome (IBS), gastritis-duodenitis, gastroesophageal reflux disease (GERD), and diverticular disease, but not inflammatory bowel disease (IBD).
View Article and Find Full Text PDFInt J Med Microbiol
June 2024
Lab of Microbiology, Department of Clinical Laboratory, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China; Nosocomial Infection Control Department, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China. Electronic address:
Background: The increasing prevalence of antibiotic-resistant Helicobacter pylori strains poses a significant threat to children's health. This study investigated antibiotic resistance rates in Helicobacter pylori strains isolated from children in Shanghai and analyzed the presence of virulence genes in these strains.
Methods: We obtained 201 Helicobacter pylori strains from pediatric patients with upper gastrointestinal symptoms who underwent gastrointestinal endoscopy between 2019 and 2022.
Pan Afr Med J
May 2024
Department of Public Health and Community Medicine, University of Benin Teaching Hospital, Edo State, Nigeria.
Introduction: Health-related quality of life (HRQoL) examines the impact of the symptoms of dyspepsia on the daily life of sufferers. There are a few published studies related to HRQoL of persons with dyspepsia in Africa.
Methods: this was a hospital-based cross-sectional study involving 324 dyspeptic patients referred for upper gastrointestinal endoscopy to the University of Benin Teaching Hospitals (UBTH) The ROME IV criteria were used to recruit patients with dyspepsia.
J Assoc Physicians India
December 2023
Consultant, Department of Gastroenterology, North Bengal Hospital, Kolkata, West Bengal, India.
Gene
August 2024
Centre for Medical Biotechnology, Amity Institute of Biotechnology, Amity University, Noida 201301, UP, India. Electronic address:
Introduction: Outer membrane protein (OMP) of Helicobacter pylori (H. pylori) i.e.
View Article and Find Full Text PDFHelicobacter
April 2024
Beijing Key Laboratory for Helicobacter pylori Infection and Upper Gastrointestinal Diseases, Department of Gastroenterology, Peking University Third Hospital, Beijing, China.
Background: Helicobacter pylori infection is one of the main causes of gastric cancer. thioredoxin-1 (Trx1) and arginase (RocF) expressed by H. pylori were found to be closely related to its pathogenicity.
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