8,718 results match your criteria: "Gastritis and Peptic Ulcer Disease"

() infections may cause chronic gastritis, peptic ulcer disease, gastric cancers, and other conditions outside of the gastrointestinal tract. Hence, it is important to diagnose and treat it early. is resistant to certain drugs in traditional eradication therapy, so alternative therapy protocols are needed, such as high-dose amoxicillin dual therapy (HDADT).

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The Aging Stomach: Clinical Implications of Infection in Older Adults-Challenges and Strategies for Improved Management.

Int J Mol Sci

November 2024

Department of Medicine, Academy of Applied Medical and Social Sciences-AMiSNS: Akademia Medycznych I Spolecznych Nauk Stosowanych, 82-330 Elbląg, Poland.

Aging is a multifactorial biological process characterized by a decline in physiological function and increasing susceptibility to various diseases, including malignancies and gastrointestinal disorders. Helicobacter pylori () infection is highly prevalent among older adults, particularly those in institutionalized settings, contributing to conditions such as atrophic gastritis, peptic ulcer disease, and gastric carcinoma. This review examines the intricate interplay between aging, gastrointestinal changes, and pathogenesis.

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Alleviation of Helicobacter pylori- or aspirin-induced gastritis and neuroinflammation in mice by lactococcus lactis and bifidobacterium longum.

Lett Appl Microbiol

December 2024

Neurobiota Research Center, College of Pharmacy, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea.

Helicobacter pylori (HP) causes gastritis and peptic ulcer. Therefore, we examined whether probiotics Lactococcus lactis P135 and Bifidobacterium longum P142, which inhibited HP growth by 37.9% and 35.

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Prevalence of infection in China from 2014-2023: A systematic review and meta-analysis.

World J Gastroenterol

November 2024

Department of Acquired Immune Deficiency Syndrome Treatment and Research Center, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou 450000, Henan Province, China.

Article Synopsis
  • The text outlines that a specific bacterium is the main cause of gastritis, peptic ulcers, and gastric cancer, and is recognized as a group 1 carcinogen by the World Health Organization, particularly impacting public health in China.* -
  • A systematic review and meta-analysis were conducted, involving 152 studies and over 763,000 individuals, revealing an overall infection rate of 42.8% in mainland China, with the highest rates found in Northwest China and specific regions like Qinghai Province.* -
  • The study indicated that while the infection prevalence has decreased in recent years, it remains notable among the elderly compared to children, highlighting the need for targeted prevention strategies in public health policies.*
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Surgical Management of Non-ulcer, Nonneoplastic Gastric Perforations.

Surg Clin North Am

February 2025

Department of Surgery, NYU Langone Hospitals - Brooklyn, 150 55th Street, Brooklyn, NY 11220, USA. Electronic address:

Article Synopsis
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Vonoprazan: A novel agent used in eradicating Helicobacter pylori infection.

JAAPA

December 2024

At Wake Forest University School of Medicine in Winston-Salem, N.C., Delaney Provenza is an assistant professor in the PA program and John Michael Provenza is an assistant professor of gastroenterology. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Helicobacter pylori is the most common chronic bacterial infection worldwide. Because of the risk for chronic gastritis, peptic ulcer disease, and gastric malignancy, all patients with H. pylori should be treated.

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Association of infection and white blood cell count: a cross-sectional study.

BMJ Open

November 2024

Department of Gastroenterology, Shenmu Hospital, The Affiliated Hospital of Northwest University. Faculty of Life Sciences and Medicine, Northwest University, Guangming Road, Shenmu, China

Article Synopsis
  • This study investigates the relationship between the presence of Gram-negative bacteria, specifically Helicobacter pylori (Hp), and white blood cell (WBC) counts in individuals undergoing physical exams, noting that Hp can lead to digestive issues like gastritis and ulcers.* ! -
  • Data from 864 participants showed that those infected with Hp had significantly higher WBC counts compared to those without the infection, suggesting a possible link between Hp infection and immune response.* ! -
  • Statistical analyses revealed a positive correlation between the number of Hp bacteria (measured through a breath test) and WBC counts, indicating that higher infection levels may lead to increased WBC counts in the body.* !
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Opportunities for Eradication beyond Conventional Antibiotics.

Microorganisms

September 2024

Helicobacter Pylori and Microbiota Study Group, Institute of Tropical Disease, Universitas Airlangga, Surabaya 60286, Indonesia.

Article Synopsis
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Detection, isolation and virulence characterization of Helicobacter suis from pork products aimed to human consumption.

Int J Food Microbiol

January 2025

Centro Avanzado de Microbiología Aplicada, Universitat Politècnica de València, Camino de Vera s/n, 46022 València, Spain. Electronic address:

Article Synopsis
  • Helicobacter suis is a common non-H. pylori Helicobacter that can lead to several health issues, including gastritis and neurodegenerative disorders like Parkinson's disease, and its pathogenicity varies among strains.
  • A study aimed to determine the prevalence of H. suis in pork products, finding it in 28.6% of samples, with 3 isolates showing the αCgT virulence gene and some exhibiting antibiotic multiresistance.
  • The research successfully used PCR and Fluorescence in situ Hybridization (FISH) methods to quickly and specifically detect H. suis in pork, highlighting its potential significance as a zoonotic pathogen.
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Article Synopsis
  • Upper gastrointestinal (UGI) symptoms are frequently noted in patients at health facilities, but limited access to endoscopy services has hindered the understanding of common UGI diseases in the region.
  • A study conducted in Asella, Ethiopia, involving 279 patients undergoing esophagogastroduodenoscopy (EGD), found that 74% had abnormal endoscopic results, primarily due to dyspepsia and concerns about cancers.
  • The most prevalent abnormal findings included esophageal cancer (10.4%) and gastric cancer (10%), with a recommendation for healthcare providers to be vigilant for these cancers in patients showing severe UGI symptoms.
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Study of Prevalence of Gastritis Caused by and Correlation of Urease Test with Serology (ELISA) Test.

J Pharm Bioallied Sci

July 2024

Transfusion Medicine and Blood Bank, AIIMS Bhopal, Madhya Pradesh, India.

Article Synopsis
  • The study investigates the prevalence of a particular bacterial infection in patients showing symptoms related to gastritis and peptic ulcers, which are linked to serious gastrointestinal diseases.
  • A total of 67 patients were analyzed, revealing that 43% tested positive for the infection, with various endoscopic findings, including stomach ulcers and nonulcer dyspepsia.
  • The urease test used in the study is noted for its quick results and high accuracy, but its invasive nature limits its acceptance among patients.
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H. pylori infects approximately 50% of the world's population that causes chronic gastritis, and may lead to peptic ulcer disease (PUD). H.

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Gastritis and gastric ulcers are common gastric diseases that are caused by infection, drugs, alcohol consumption, or stress. These conditions lead to increased inflammatory cytokines and recruitment of leukocytes, which damage the stomach mucosa and exacerbate disease severity. (SA), an annual vine in the family, is known to have an anti-inflammatory effect, but its efficacy for preventing gastritis and gastric ulcers has not yet been evaluated.

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Article Synopsis
  • This study looked at patients with liver cirrhosis at a hospital in Ghana to understand how the disease affects their stomach and esophagus.
  • They found that many patients had symptoms like tiredness and swelling, with most being older men in a severe stage of the disease.
  • The most common issue spotted during examinations was esophageal varices, which are bulging veins related to the condition, along with other stomach problems.
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Review of foodborne helicobacteriosis.

Ital J Food Saf

August 2024

Department of Pharmacy, College of Pharmacy, Knowledge University, Erbil, Iraq.

Article Synopsis
  • Helicobacteriosis is a bacterial infection affecting the stomach and small intestines, primarily spread through contaminated food or water.
  • The infection is often contracted in childhood from close family members, with crowded living conditions increasing the risk of transmission.
  • The review highlights detection challenges, especially in the dormant phase, and discusses advanced techniques for tracing bacteria, emphasizing the need for long-term studies to better understand transmission dynamics.
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Incidence of Gastric Foveolar Metaplasia in Duodenal Mucosa of the Pediatric Patients.

Ann Clin Lab Sci

July 2024

Department of Pathology and Laboratory Medicine, Yale University Medical School, New Haven, CT, USA.

Objective: The prevalence and the clinical significance of gastric foveolar metaplasia (GFM) of duodenal mucosa in pediatric patients are undetermined. The aim was to investigate the event of GFM in duodenal biopsies and its association with gastrointestinal tract disorders in pediatric patients.

Methods: We performed a chart review of the characteristics and pathologic findings in patients with GFM described in the pathology reports during 2020 to 2022.

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is a bacterium that may colonise and proliferate in human stomachs, leading invariably to chronic inflammation and, to a lesser extent, to peptic ulcers and cancer. The main objective of this study is to describe the epidemiology surrounding in Nunavik's Inuit population using the 2004 and 2017 Health Surveys. Estimated prevalences were 70.

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Article Synopsis
  • The study aimed to investigate how Helicobacter pylori infection affects gastric lesions in patients with non-eosinophilic gastrointestinal diseases (non-EoE EGIDs).
  • A review of 75 patients found that common gastric findings included erythema, erosions, ulcers, and edema, with no significant differences based on gastric mucosal atrophy, which indicates H. pylori infection.
  • The researchers concluded that gastric ulcers in non-EoE EGIDs should be considered when diagnosing idiopathic peptic ulcers, as there was no specific pattern in lesion frequency related to atrophic gastritis.
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Article Synopsis
  • Helicobacter pylori infects over half of the global population and is the leading cause of chronic gastritis, which can result in serious conditions like peptic ulcers and stomach cancer, particularly in Colombia where infection rates exceed 80%.
  • A study in Pereira, Colombia analyzed five H. pylori isolates from patients with different gastritis severities, revealing that all were resistant to at least one antimicrobial and had distinct genetic traits associated with virulence.
  • The findings underscore the diversity in antimicrobial resistance and genome characteristics of H. pylori in gastritis cases, which can inform more effective treatment strategies tailored to specific infections.
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