4 results match your criteria: "Ganzhou People's Hospital. No. 16[Affiliation]"

Construction of a mitophagy-related prognostic signature for predicting prognosis and tumor microenvironment in lung adenocarcinoma.

Heliyon

August 2024

Department of Respiratory and Critical Care Medicine, The Affiliated Ganzhou Hospital of Nanchang University, Ganzhou People's Hospital. No. 16, Meiguan Avenue, Zhanggong, Ganzhou, Jiangxi, 341000, PR China.

Background: Mitophagy is the selective degradation of mitochondria by autophagy. It becomes increasingly clear that mitophagy pathways are important for cancer cells to adapt to their high-energy needs. However, which genes associated with mitophagy could be used to prognosis cancer is unknown.

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Article Synopsis
  • The study aimed to evaluate the effectiveness of combining estriol valerate and progesterone in preventing intrauterine adhesions (IUA) in patients who suffered early missed abortions after dilation and curettage.
  • Data from 120 patients were analyzed; 70 received the treatment while 50 did not, with results showing a significantly better response to the treatment in preventing IUA.
  • Key risk factors for developing IUA included a history of multiple miscarriages, small endometrial volume, thin endometrial thickness, and the absence of preventive treatment.
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  • The immune microenvironment is crucial for bone formation (osteoanagenesis) and can be influenced by biomaterials that trigger specific local immune responses.
  • Advancements in 3D-printing, especially using digital light projection, allow for the creation of precise biomaterial scaffolds with controlled pore sizes, which affects their osteogenic efficacy.
  • In our study, hydroxyapatite scaffolds with a pore size of 600 μm improved macrophage M2 polarization and led to better inflammatory responses, vascular growth, and new bone development when implanted in animals, indicating promising applications for treating large bone defects.
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Xihuang pill induces pyroptosis and inhibits progression of breast cancer cells via activating the cAMP/PKA signalling pathway.

Am J Cancer Res

April 2023

Department of Traditional Chinese Medicine, Ganzhou People's Hospital No. 16, MeiGuan Road, Zhanggong District, Ganzhou 341000, Jiangxi, China.

Xihuang pill (XHP), a traditional Chinese medicine, has been shown to be effective for breast cancer (BC) therapy in clinical trials. However, the molecular mechanism of XHP in BC remains unclear. The molecular mechanism of XHP in BC was investigated by generating murine mammary carcinoma 4T1 cell xenografts.

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