is Expressed on the Left Side of the Brain Vesicle in the Ascidian Larva.

The ascidian larvae, which display a chordate ground body plan, are left-right asymmetric in several structures, including the brain vesicle. In ascidian larvae, the ocellus and otolith pigment cells, which are thought to detect light and gravity respectively, are located on the right side of the brain vesicle, while the coronet cells, which are presumed to be dopaminergic, are located on the left side. To study how left-right asymmetry of the brain vesicle in the ascidian larva is determined, I attempted to isolate a gene that is expressed in the brain vesicle.

Production and application of Paenibacillus polymyxa levan as an antiviral priming agent against cucumber mosaic virus infection in tobacco plants.

This study investigates the application of levan- produced from Paenibacillus polymyxa SG09-12 as an antiviral agent against cucumber mosaic virus (CMV). A high-purity microbial levan was produced and purified using diafiltration. The chemical composition, structure, and functional groups of the levan were characterised using high-performance liquid chromatography (HPLC), nuclear magnetic resonance (NMR), Fourier-transform infrared spectroscopy (FT-IR), and X-ray photoelectron spectroscopy (XPS).

Evaluation of Perceptual and Anthropometrical Facial Changes According to Increase in Vertical Dimension of Occlusion.

Background: For restorative demands, increased vertical dimension of occlusion (VDO) is sometimes necessary, as facial changes can be perceptible.

Objectives: This study aimed to evaluate the perception of facial change due to increased VDO and associated soft tissue changes using 3D-scanned facial images.

Methods: Forty participants with healthy dentition and no loss of VDO were recruited.

Circadian clock regulation in soybean senescence: a transcriptome analysis of early and late senescence types.

Background: Plant senescence is the process of physiological maturation of plants and is important for crop yield and quality. Senescence is controlled by several factors, such as temperature and photoperiod. However, the molecular basis by which these genes promote senescence in soybeans is not well understood.

and canine periodontal disease: Current understanding and future directions.

has emerged as a notable pathogen in canine periodontal disease, akin to in human periodontitis. This review examines the initial isolation, phylogenetic analysis, habitat, host range, relationships with host health status and age, and key pathogenic determinants, including fimbriae, proteases, citrullinating enzyme, and lipopolysaccharide. Control strategies discussed include polyphosphate to disrupt haeme/iron utilization, clindamycin with interferon alpha to reduce bacterial load and enhance the immune response, and a protease inhibitor.

A comprehensive overview of FFRG and IHCC allograft cartilages in revision rhinoplasty: a systematic review.

Background: This study aims to compare the complications and satisfaction associated with favorable allografts, Fresh Frozen Rib Graft (FFRG) and Irradiated Homologous Costal Cartilage (IHCC), in revision rhinoplasty.

Methods: The PRISMA guidelines were adhered to in the conduct of this systematic review. No limitations were applied to the types of studies included.

Therapeutic potential of 4-hexylresorcinol in reducing sarcopenia in diabetic masseter muscle.

Background: This study aimed to evaluate the effects of 4-hexylresorcinol (4HR), a synthetic compound with antioxidant and stress-modulating properties, on diabetic sarcopenia in the masseter muscle.

Methods: A controlled, parallel-arm study was conducted using 38 Sprague-Dawley rats divided into diabetic and non-diabetic groups. Diabetes was induced with streptozotocin (STZ), and the groups were further subdivided to receive weekly subcutaneous injections of either 4HR or saline.

Consumption of fruits, vegetables, and nuts influences the association between serum uric acid and hypertension in Korean adults: A nationwide survey (KNHANES 2016-2021).

Background And Objectives: This study investigated the influence of dietary intake on the relationship between serum uric acid (SUA) levels and the risk of hypertension.

Methods And Study Design: Data from the 7th and 8th Korean National Health and Nutrition Examination Survey, a nationally representative survey, were analyzed. A total of 19,140 adults aged 19-64 years were included.

Effect of scan path on accuracy of complete arch intraoral scan.

Purpose: This study aimed to compare the accuracy of an alternative scan path with that of traditional scan paths to obtain a more accurate method for complete arch scans.

Materials And Methods: A mandibular stone cast, including tooth preparations for the inlay, crown, and fixed prosthesis, was scanned 10 times using four different scan paths (A, B, C, and D). The scans were converted into stereolithography files, resized, and superimposed onto a control file obtained from a desktop scanner.

High air pollution exposure, vitamin D deficiency and ever smokers were associated with higher prevalence of hypercholesterolemia: A cross-sectional study from the 2008-2014 Korea National Health and Nutrition Examination Survey.

Air pollutants directly and indirectly cause vitamin D deficiency (VDD). In addition, smoking increases oxidative stress and accelerates skin aging, thereby reducing the body's vitamin D concentration. Previous study reported that VDD increases total cholesterol concentration by reducing vitamin D receptor activity.

A Novel Eco-Friendly Process for the Synthesis and Purification of Ascorbyl-6-Oleates.

Commercial ascorbyl-6-O-esters (AEs) are composed of saturated fatty acids with relatively high melting points, resulting in limited solubility in lipophilic media. Therefore, a lipase-catalysed synthesis and purification method for ascorbyl-6-O-oleate (AO) was proposed in this study. The esterification synthesis (i.

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments.

The dynamics of focal adhesions (FAs) are essential physiological processes involved in cell spreading, metastasis, and regulation of the actin cytoskeleton. FAs are complex structures comprising proteins, such as paxillin and zyxin, which interact with extracellular membranes and influence cell motility and morphology. Although related studies have been reported in various cancers, the function and molecular mechanisms of oral squamous cell carcinoma (OSCC) remain unknown.

Effect of crystallization and finish line curvature on the marginal integrity of lithium disilicate crowns.

Purpose: This study aimed to investigate the effect of crystallization and finish line curvature on the integrity of lithium disilicate crowns fabricated by using partially crystallized (P) and fully crystallized (F) blocks.

Materials And Methods: Forty-eight lithium disilicate crowns were fabricated based on the designated lithium disilicate blocks and finish line curvatures. The specimens were divided into four groups (n = 12 each): P block with a curved finish line (PC), P block with a straight finish line (PS), F block with a curved finish line (FC), and F block with a straight finish line (FS).

Guidance and Considerations When Performing Data-Validity Checks.

This response to a Commentary by Delgado-Ron, Jeyabalan, Watt, and Salway (2024) on Cimpian, Timmer, and Kim's (2023) paper discusses and clarifies some key issues in applying the new data-validity sensitivity analysis proposed by Cimpian et al. (2023). The differences in the applications of the method by Delgado-Ron et al.

Benzo(a)pyrene and Gut Microbiome Crosstalk: Health Risk Implications.

This review delves into the impact of benzo(a)pyrene (B(a)P), which is a toxic and pervasive polycyclic aromatic hydrocarbon (PAH) and known carcinogen, on the human health risk from a gut microbiome perspective. We retrieved the relevant articles on each PAH and summarized the reporting to date, with a particular focus on benzo(a)pyrene, which has been reported to have a high risk of gut microbiome-related harm. B(a)P exposure can compromise the homeostasis of the gut microbiota, leading to dysbiosis, a state of microbial imbalance.

Role of Filter-Feeding Bivalves in the Bioaccumulation and Transmission of White Spot Syndrome Virus (WSSV) in Shrimp Aquaculture Systems.

White spot syndrome virus (WSSV) poses a major risk to shrimp aquaculture, and filter-feeding bivalves on shrimp farms may contribute to its persistence and transmission. This study investigated the bioaccumulation and vector potential of WSSV in Pacific oysters (), blue mussels (), and manila clams () cohabiting with WSSV-infected shrimp. Sixty individuals of each species (average shell lengths: 11.

Seasonal Water-Column Structure Drives the Trophic Niche of Fish Communities on a Temperate Continental Shelf.

In seasonally stratified marine environments, the dynamics of benthic-pelagic coupling plays a crucial role in shaping food web structures and fisheries production. We examined fish food web structures across three distinct shelf areas in the Southern Sea of Korea (SSK) during both stratified (summer) and mixed (spring) water conditions using stable isotopes of carbon (δC) and nitrogen (δN). In spring, fish communities exhibited a broader range of δC values compared with summer, indicating more diverse feeding strategies.

Coastal vulnerability to extreme weather events: An integrated analysis of erosion, sediment movement, and land subsidence based on multi-temporal optical and SAR satellite data.

Coastal areas undergo continuous transformations, altering their geometry under the influence of external forces like tides, waves, and extreme events. Thus, monitoring the impact of extreme weather events on coastal regions is crucial to prevent potential cascading hazards. Here, we utilized time-series optical and SAR satellite data and tide records, coupled with sophisticated analytical techniques, to analyze erosion processes, sediment transport, and vertical land movement (VLM) at an embayed sandy beach (i.

Novel contribution to the taxonomy and molecular phylogeny of scuticociliates (Protozoa): Resolving the non-monophyly of the genus Paranophrys Thompson and Berger, 1965 and the establishment of the genus Anteparanophrys n. gen.

During a field survey of parasitic ciliates diversity in South Korea, a scuticociliate was found in a water sample collected during scuba diving. At first glance, the species looks similar to members of the genus Paranophrys especially P. magna but they differ mainly in the body size and the number of somatic kineties.

Anti-inflammatory and osteoconductive multi-functional nanoparticles for the regeneration of an inflamed alveolar bone defect.

Infected alveolar bone defects pose challenging clinical issues due to disrupted intrinsic healing mechanisms. Thus, the employment of advanced biomaterials enabling the modulation of several aspects of bone regeneration is necessary. This study investigated the effect of multi-functional nanoparticles on anti-inflammatory/osteoconductive characteristics and bone repair in the context of inflamed bone abnormalities.

Delayed inflammation after biodegradable and osteoconductive osteofixation in orthognathic surgery.

Objectives: This study aims to identify patterns and to describe the clinical course of delayed adverse tissue responses in patients who underwent orthognathic osteotomy with biodegradable osteofixation.

Patients And Methods: Through a retrospective review of cases between 2013 and 2020, we identified three patients who underwent bimaxillary osteotomy and fixation with unsintered-hydroxyapatite/poly-L lactic acid (u-HA/PLLA) devices, after which they developed delayed inflammation. These lesions were treated with drainage and/or removal of the devices.

Establishment of an oral burn model in streptozotocin-induced diabetic rats.

Background: Oral ulcers are painful mucosal lesions prone to infection and inflammation. To evaluate the effectiveness of treatments, a suitable experimental animal model with an appropriate healing period is required. The aim of this study was to develop an animal model for oral ulcer research by comparing oral burn wounds of different sizes and locations in diabetic rats.

Cultural heritage site selection characteristics and the impact of the natural environment in Jinan city, China.

This study aims to explore the spatial distribution and site selection characteristics of cultural heritage sites, as well as the impact of the natural environment on the site's location. A total of 448 cultural heritage sites in Jinan City (Shandong province), which have been listed as key cultural relic protection units from before the Qin Dynasty to after the Qing Dynasty (ca. 7500 BCE-present), were analyzed using spatial analysis tools in ArcGIS 10.

The Dual Role of Survival Genes in Neurons and Cancer Cells: a Strategic Clinical Application of DX2 in Neurodegenerative Diseases and Cancer.

In cancer cells, survival genes contribute to uncontrolled growth and the survival of malignant cells, leading to tumor progression. Neurons are post-mitotic cells, fully differentiated and non-dividing after neurogenesis and survival genes are essential for cellular longevity and proper functioning of the nervous system. This review explores recent research findings regarding the role of survival genes, particularly DX2, in degenerative neuronal tissue cells and cancer cells.

Edge Chipping Resistance and Flexural Strength of CAD-CAM Ceramics Before and After Thermomechanical Aging.

Objectives: To evaluate the complementary mechanical properties of dental ceramics using edge chipping resistance (Rea) and flexural strength before and after thermomechanical aging.

Material And Methods: Computer-aided design and computer-aided manufacturing of ceramic materials, including zirconia (ZR), lithium disilicate (LS2), and resin nanoceramics (RNC), were evaluated. Specimens for flexural strength testing were fabricated with dimensions of 3 × 4 × 25 mm, with 30 specimens per group.