Novel contribution to the taxonomy and molecular phylogeny of scuticociliates (Protozoa): Resolving the non-monophyly of the genus Paranophrys Thompson and Berger, 1965 and the establishment of the genus Anteparanophrys n. Gen.

During a field survey of parasitic ciliates diversity in South Korea, a scuticociliate was found in a water sample collected during scuba diving. At first glance, the species looks similar to members of the genus Paranophrys especially P. magna but they differ mainly in the body size and the number of somatic kineties.

Anti-inflammatory and osteoconductive multi-functional nanoparticles for the regeneration of an inflamed alveolar bone defect.

Infected alveolar bone defects pose challenging clinical issues due to disrupted intrinsic healing mechanisms. Thus, the employment of advanced biomaterials enabling the modulation of several aspects of bone regeneration is necessary. This study investigated the effect of multi-functional nanoparticles on anti-inflammatory/osteoconductive characteristics and bone repair in the context of inflamed bone abnormalities.

Delayed inflammation after biodegradable and osteoconductive osteofixation in orthognathic surgery.

Objectives: This study aims to identify patterns and to describe the clinical course of delayed adverse tissue responses in patients who underwent orthognathic osteotomy with biodegradable osteofixation.

Patients And Methods: Through a retrospective review of cases between 2013 and 2020, we identified three patients who underwent bimaxillary osteotomy and fixation with unsintered-hydroxyapatite/poly-L lactic acid (u-HA/PLLA) devices, after which they developed delayed inflammation. These lesions were treated with drainage and/or removal of the devices.

Establishment of an oral burn model in streptozotocin-induced diabetic rats.

Background: Oral ulcers are painful mucosal lesions prone to infection and inflammation. To evaluate the effectiveness of treatments, a suitable experimental animal model with an appropriate healing period is required. The aim of this study was to develop an animal model for oral ulcer research by comparing oral burn wounds of different sizes and locations in diabetic rats.

Cultural heritage site selection characteristics and the impact of the natural environment in Jinan city, China.

This study aims to explore the spatial distribution and site selection characteristics of cultural heritage sites, as well as the impact of the natural environment on the site's location. A total of 448 cultural heritage sites in Jinan City (Shandong province), which have been listed as key cultural relic protection units from before the Qin Dynasty to after the Qing Dynasty (ca. 7500 BCE-present), were analyzed using spatial analysis tools in ArcGIS 10.

The Dual Role of Survival Genes in Neurons and Cancer Cells: a Strategic Clinical Application of DX2 in Neurodegenerative Diseases and Cancer.

In cancer cells, survival genes contribute to uncontrolled growth and the survival of malignant cells, leading to tumor progression. Neurons are post-mitotic cells, fully differentiated and non-dividing after neurogenesis and survival genes are essential for cellular longevity and proper functioning of the nervous system. This review explores recent research findings regarding the role of survival genes, particularly DX2, in degenerative neuronal tissue cells and cancer cells.

Edge Chipping Resistance and Flexural Strength of CAD-CAM Ceramics Before and After Thermomechanical Aging.

Objectives: To evaluate the complementary mechanical properties of dental ceramics using edge chipping resistance (Rea) and flexural strength before and after thermomechanical aging.

Material And Methods: Computer-aided design and computer-aided manufacturing of ceramic materials, including zirconia (ZR), lithium disilicate (LS2), and resin nanoceramics (RNC), were evaluated. Specimens for flexural strength testing were fabricated with dimensions of 3 × 4 × 25 mm, with 30 specimens per group.

Role of Mindfulness in the Effects of Organizational Culture on Depression in Korean Physical Therapists.

Objective: The study aimed to investigate whether mindfulness could mitigate the impact of job and interpersonal demands arising from stressful organizational cultures in predicting depression during the COVID-19 pandemic.

Methods: A total of 280 Korean physical therapists participated in this study. To verify the mediated moderation model, this study implemented an SPSS 26.

The Application of L-Serine-Incorporated Gelatin Sponge into the Calvarial Defect of the Ovariectomized Rats.

Background: Osteoporosis, characterized by decreased bone mineral density due to an imbalance between osteoblast and osteoclast activity, poses significant challenges in bone healing, particularly in postmenopausal women. Current treatments, such as bisphosphonates, are effective but associated with adverse effects like medication-related osteonecrosis of the jaw, necessitating safer alternatives.

Methods: This study investigated the use of L-serine-incorporated gelatin sponges for bone regeneration in calvarial defects in an ovariectomized rat model of osteoporosis.

Current-vortex-sheet model of the magnetic Rayleigh-Taylor instability.

This study investigates the Rayleigh-Taylor instability in the magnetic field applied parallel to the interface. The motion of the interface is described using a current-vortex-sheet model. The growth rate of the interface is obtained from a linear stability analysis of the model.

Comparison of Fluid Flow Rates by Fluid Height and Catheter Size in Normal and Hypertensive Blood-Pressure Scenarios.

Objectives: This study is performed to determine the effects of fluid height, inner catheter diameter, and peripheral venous pressure on room-temperature intravenous fluid administration.

Methods: We employed the Bernoulli equation, with frictional forces considered for volumetric analysis.

Results: The results of this study demonstrate that infusion-set height, catheter size, fluid type, and blood pressure significantly affect flow rates.

COVID-19-Related Knowledge, Fear, and Infection Control of Dental Staff.

Objective: This study aimed to investigate the correlations between knowledge, fear, infection control practices, and attitude of dental staff in Korea.

Methods: This study was conducted to investigate the correlation between COVID-19-related knowledge, fear, and infection control attitudes and practices.

Results: COVID-19-related knowledge was significantly correlated with infection control attitudes and practices (r = 0.

[Validity and Reliability of the Korean Version of the Occupational Coping Self-Efficacy Scale for Nurses].

Purpose: This study aimed to evaluate the validity and reliability of the Korean version of the occupational coping self-efficacy for nurses (K-OCSE-N) scale.

Methods: The English version of the OCSE-N scale was translated into Korean using a translation and back-translation process. Data were gathered from 213 nurses employed in a general hospital in South Korea.

Descriptions of three new species of Philodinida (Rotifera, Bdelloidea) from Korea.

A taxonomic study on bdelloid rotifers collected from terrestrial habitats such as mosses and leaf litter at two different locations in Korea resulted in three new species, Habrotrocha changhoi n. sp., H.

Integrative studies shed light on the pseudocryptic genus Crassohymena n. gen. (Protozoa, Ciliophora).

The morphology, morphogenesis, molecular phylogeny, and the resting cyst morphology of the freshwater ciliate, Crassohymena primicirrata (Berger and Foissner, 1987) n. gen., n.

Enhancing bone regeneration and osseointegration using rhPTH(1-34) and dimeric PTH(1-34) in an osteoporotic beagle model.

This study investigates the effects of two parathyroid hormone (PTH) analogs, rhPTH(1-34) and dimeric PTH(1-34), on bone regeneration and osseointegration in a postmenopausal osteoporosis model using beagle dogs. Twelve osteoporotic female beagles were subjected to implant surgeries and assigned to one of three groups: control, rhPTH(1-34), or dimeric PTH(1-34). Bone regeneration and osseointegration were evaluated after 10 weeks using micro-computed tomographic (micro-CT), histological analyses, and serum biochemical assays.

Host-specific effects of Eubacterium species on Rg3-mediated modulation of osteosarcopenia in a genetically diverse mouse population.

Background: Osteosarcopenia, characterized by the simultaneous loss of bone and muscle mass, is a serious health problem in the aging population. This study investigated the interplay between host genetics, gut microbiota, and musculoskeletal health in a mouse model of osteosarcopenia, exploring the therapeutic potential of gut microbiota modulation.

Methods: We examined the effects of Rg3, a phytochemical, on osteosarcopenia and its interactions with host genetics and gut microbiota in six founder strains of the Collaborative Cross (CC) population.

Neuroprotective Effects of Chaperonin Containing TCP1 Subunit 2 (CCT2) on Motor Neurons Following Oxidative or Ischemic Stress.

Chaperonin containing TCP1 (CCT) is an essential protein that controls proteostasis following spinal cord damage. In particular, CCT2 plays an important role in neuronal death in various neurological disorders; however, few studies have investigated the effects of CCT2 on ischemic damage in the spinal cord. In the present study, we synthesized a cell-permeable Tat-CCT2 fusion protein and observed its effects on HO-induced oxidative damage in NSC34 motoneuron-like cells and in the spinal cord after ischemic injury.

Spontaneous detection of F and viscosity using a multifunctional tetraphenylethene-lepidine probe: Exploring environmental applications.

Excessive fluoride ions (F) in drinking water and food is harmful for human health and the environment. Therefore, a fluorescent probe tetraphenylethylene-quinoline (P-1) is developed with multiple sensing properties for the sequential detection of tert-butyldiphenylsilyl chloride (TBDS), F, and viscosity. Sensor P-1 first recognized TBDS and then observed an intramolecular charge transfer process, which produced an intermediate sensor P-2 in addition to fluorescence quenching at 576 nm.

Disparities in Health and Oral Health Behaviors Among Adolescents from Multicultural Families in South Korea.

This study analyzed changes over time in order to identify disparities in health and oral health behaviors among adolescents from multicultural families residing in Korea. This was a cross-sectional analysis of secondary data utilizing raw data from 2011 to 2022 from the Korea Youth Risk Behavior Survey, a statistical dataset provided by the Korea Disease Control and Prevention Agency. The variables included demographic characteristics, socioeconomic characteristics, health behavior (diet, alcohol consumption, smoking), and oral health behavior (toothbrushing behavior, preventive care behavior, oral symptom experience, and school-based oral health education experience).

A novel targeted anticancer drug delivery strategy: Cnidium officinale polysaccharide conjugated with carboxymethyl-5-fluorouracil and folic acid for ovarian cancer therapy.

To mitigate adverse reactions induced by 5-fluorouracil (5-FU), Cnidium officinale fraction 2 (F2) polysaccharides served as the macromolecular carrier, facilitating its reaction with carboxymethyl-5-fluorouracil (C-5-FU) for producing F2-C-5-FU. Subsequently, this compound could react with folic acid (FA) through the ester bond, forming F2-C-5-FU-FA, as verified through NMR analysis. The in vitro anticancer efficacy of F2-C-5-FU-FA was evaluated using SKOV-3 cells that expressed folate receptor (FR) and FR-deficient A549 cells, showing greater cytotoxicity in the SKOV-3 cell line due to the FRs on the cell membrane.

Obesity Risk Was Associated with Alcohol Intake and Sleep Duration Among Korean Men: The 2016-2020 Korea National Health and Nutrition Examination Survey.

Background/objectives: Excessive alcohol drinking and short sleep duration could be problematic in terms of obesity. This research investigated the risk of obesity according to alcohol consumption and sleep duration, using data from the 2016-2020 Korea National Health and Nutrition Examination Survey (KNHANES).

Methods: The health behavior survey on alcohol intake and sleep duration was conducted via self-reporting by participants.

4-Hexylresorcinol Enhances Glut4 Expression and Glucose Homeostasis via AMPK Activation and Histone H3 Acetylation.

This study investigates the potential of 4-hexylresorcinol (4HR) as a novel antidiabetic agent by assessing its effects on blood glucose levels, Glut4 expression, AMPK phosphorylation, and Histone H3 acetylation (Ac-H3) in the liver. In vitro experiments utilized Huh7 and HepG2 cells treated with varying concentrations of 4HR. Glut4, p-AMPK, and Ac-H3 expression levels were quantified via Western blotting.

Neuroprotective Effects of Ethanol Extract (EEPG) Against Glutamate Induced Neurotoxicity in HT22 Cells.

Oxidative stress induced by glutamate is a significant contributor to neuronal cell damage and can lead to neurodegenerative diseases such as Alzheimer's, Huntington's, and ischemic brain injury. At the cellular level, oxidative stress increases Ca ion influx and reactive oxygen species (ROS), which activate the MAPK signaling pathway. Additionally, the generation of ROS causes mitochondrial dysfunction, triggering apoptosis by promoting the translocation of AIF to the nucleus from the mitochondria.

Distribution of Dietary Phospholipids in Selected Agri-Foods: Versatile Nutraceutical Ingredients.

Phospholipids (PLs) play a crucial role in the nutraceutical field due to their various health benefits, including supporting acetylcholine production, enhancing cell membrane fluidity, and promoting cognitive functions. This study aimed to investigate the PL composition of selected agri-foods, including grains, vegetables, and fruits, and assess the effects of cooking methods. The major PLs identified in most agri-foods were phosphatidylethanolamine (PE) and phosphatidylcholine (PC).