1,711 results match your criteria: "Gangneung Wonju National University[Affiliation]"

Performance management and policy evaluation of information and communication technology graduate program for developing countries.

Eval Program Plann

April 2024

Department of e-Business, School of Business Administration, Ajou University, 206 Worldcup-ro, Yeongtong-gu, Suwon, Republic of Korea. Electronic address:

As an educational aid, the Korean government has developed and funded a graduate-level global information telecommunications technology program (ITTP) for ICT officers in developing countries. Questions have arisen about whether the program can achieve its goals and obtain mutual benefits between Korea and participating nations. Using a total quality management (TQM) framework as a unique case analysis, we evaluated ITTP's resources and performance from 2006 to 2014.

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Rehabilitation addresses not only children's disabilities but also their physical, psychological, social, and cultural impairments. Hence, pediatric rehabilitation adopts a multidisciplinary approach; it encompasses the vital role of not only physicians and rehabilitation therapists, but also of nurses. This study conducts a content analysis of the experiences of healthcare professionals specializing in pediatric rehabilitation to explore the roles nurses working on pediatric rehabilitation units are expected to perform.

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Ginseng has long been widely used for its therapeutic potential. In our current study, we investigated the impact of abiotic stress induced by infrared (IR) radiations and sodium silicate on the upregulation of antioxidant and anti-tyrosinase levels, as well as the total phenolic and total flavonoid contents of the Korean ginseng ( C.A.

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Rapid, anthropogenic activity-induced global warming is a severe problem that not only raises water temperatures but also shifts aquatic environments by increasing the bioavailability of heavy metals (HMs), with potentially complicated effects on aquatic organisms, including small aquatic invertebrates. For this paper, we investigated the combined effects of temperature (23 and 28 °C) and methylmercury (MeHg) by measuring physiological changes, bioaccumulation, oxidative stress, antioxidants, and the mitogen-activated protein kinase signaling pathway in the marine rotifer Brachionus plicatilis. High temperature and MeHg adversely affected the survival rate, lifespan, and population of rotifers, and bioaccumulation, oxidative stress, and biochemical reactions depended on the developmental stage, with neonates showing higher susceptibility than adults.

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This study aimed to identify the factor structure of the Korean version of the Short Grit Scale (Grit-S) and examine its cross-sectional and longitudinal measurement invariance (MI). Data from the Korean Children and Youth Panel Survey 2018 were analyzed, which included two cohorts, comprising 2,327 and 2,325 fourth-year elementary and first-year middle school students, respectively. It was found that the two-factor model fit the data well for the elementary and middle school samples.

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Mycotoxins (ochratoxin A (20 ppb), aflatoxin B1 (40 ppb), deoxynivalenol (4 ppm), and zearalenone (800 ppb)) were intentionally added to rice bran raw materials. After fermentation, their contents were determined in the distillate and distillery stillage obtained using single-stage and continuous pilot plant-scale columns. After single-stage distillation, aflatoxin B1, deoxynivalenol, and zearalenone were not detected in the distillate, indicating that even if a certain amount (four times the maximum residue limit (MRL)) was present in the raw material, it would not remain in the distillate after fermentation and distillation.

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Purpose: This study investigates the impact of a Virtual Reality (VR)-based Mental Health Nursing Practice Simulation (MHNPS) on nursing students' competency in caring for individuals with mental disorders. Nursing students often face fear, anxiety, and helplessness during mental health (MH) rotations, impeding the attainment of learning objectives in the MH nursing practicum. Therefore, innovative strategies offering practice opportunities are crucial for their competence development.

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Background: Neurodegenerative diseases, including Parkinson's disease, Amyotropic Lateral Sclerosis (ALS) and Alzheimer's disease, present significant challenges for therapeutic development due to drug delivery restrictions and toxicity concerns. Prevailing strategies often employ adeno-associated viral (AAV) vectors to deliver neuroprotective survival genes directly into the central nervous system (CNS). However, these methods have been limited by triggering immunogenic responses and risk of tumorigenicity, resulting from overexpression of survival genes in peripheral blood mononuclear cells (PBMC), thereby increasing the risk of tumorigenicity in specific immune cells.

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A Multisite Study on the Effect of a Urinary Incontinence Self-Management Program on Community-Dwelling Older Women in Korea.

J Wound Ostomy Continence Nurs

January 2024

Sunah Park, PhD, RN, Department of Nursing, Gangneung-Wonju National University, Wonju-si, Gangwon-do, South Korea.

Purpose: The purpose of this study was to evaluate the effects of a urinary incontinence (UI) self-management program on UI symptoms, knowledge, and self-efficacy in community-dwelling older women.

Design: A 1-group pretest-posttest design.

Subjects And Setting: Participants were recruited from 14 primary healthcare posts (PHCPs) in South Chungcheong Province, rural South Korea.

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Three-dimensional morphometric study on the retromolar pad.

J Adv Prosthodont

December 2023

Department of Prosthodontics and Research Institute of Oral Science, College of Dentistry, Gangneung-Wonju National University, Gangneung, Republic of Korea.

Purpose: The aim of this study was to classify the shapes of retromolar pads and assess their morphometric differences using a 3D model.

Materials And Methods: Two hundred fully edentulous or Kennedy Class I partially edentulous patients (400 retromolar pads) were enrolled. Scan data of the definitive mandibular casts produced through functional impressions were obtained using a 3D laser scanner.

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Protective effect of Tat fused HPCA protein on neuronal cell death caused by ischemic injury.

Heliyon

January 2024

Department of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon 24252, Republic of Korea.

Article Synopsis
  • Bain ischemia causes damage to the nervous system by inducing reactive oxygen species (ROS), and HPCA may offer protective effects during this process, but it hasn't been studied in depth.
  • The study aimed to explore the protective role of a modified HPCA protein, Tat-HPCA, in ischemic injury using various cell tests and cognitive function assessments.
  • Results showed that Tat-HPCA penetrated cells, reduced apoptosis and oxidative stress, lowered calcium levels in neurons, and improved cognitive functions in an animal model, suggesting its potential as a treatment for oxidative stress-related conditions caused by ischemic injury.
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Article Synopsis
  • Parthanatos, a crucial mechanism in Parkinson's disease, involves AIMP2 activating PARP-1, but it's considered undruggable as a target due to its non-enzymatic properties; however, its splice variant DX2 may provide an alternative therapeutic strategy.
  • The study compared the interaction between AIMP2 and DX2 with PARP-1, showing that DX2 binds more effectively and reduces neuronal cell death during oxidative stress conditions like 6-OHDA and H2O2 exposure.
  • In animal models, DX2 demonstrated neuroprotective effects, improving behavior and mobility after being delivered via a viral vector in models of neurodegeneration, suggesting its potential as a therapeutic agent for Parkinson's disease
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Climate crises such as extreme weather events, natural disasters and climate change caused by climate transformations are causing much damage worldwide enough to be called a climate catastrophe. The private sector and the government across industries are making every effort to prevent and limit the increasing damage, but the results have yet to meet market demand. Therefore, this study proposes a method that uses a deep learning algorithm to predict the damage caused by typhoons.

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To improve the utilization of soluble dietary fiber (SDF) from tiger nut residues, the response surface methodology was used to optimize the conditions of superfine grinding to produce SDF with antioxidant and metal-ion-binding properties. The yield was increased (30.56%) and the average particle diameter of SDF was decreased (D50: 32.

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Objective: To evaluate the representation of environmental concepts associated with health impacts in standardized clinical terminologies.

Methods: This study used a descriptive approach with methods informed by a procedural framework for standardized clinical terminology mapping. The United Nations Global Indicator Framework for the Sustainable Development Goals and Targets was used as the source document for concept extraction.

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Currently, the preparation methods and basic physicochemical properties of starch-FA complexes have been widely studied; however, no in-depth research on the regulatory mechanism of the digestive properties of debranched starch-unsaturated FA complexes has been conducted. Therefore, six fatty acids with different carbon chains and different degrees of unsaturation were complexed with de-branched millet starch in this research, using the microwave method. Microwave millet starch-linoleic acid complex (MPS-LOA) had the highest resistant starch (RS) content, and the structure and physicochemical properties of MPS-LOA were determined using various molecular techniques.

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Unraveling the maternal and paternal origins of allotetraploid Vigna reflexo-pilosa.

Sci Rep

December 2023

Department of Agriculture, Forestry and Bioresources and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea.

The genomic structures of Vigna hirtella Ridl. and Vigna trinervia (B.Heyne ex Wight & Arn.

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Article Synopsis
  • The study focuses on low-dose ionizing radiation (LDIR), which has been understudied compared to high-dose methods due to a lack of understanding of its molecular effects.
  • Researchers developed a method to profile RNA bound to the RNA-binding protein HuR after exposure to LDIR, indicating that LDIR can protect RNA from degradation.
  • The results suggest that LDIR influences post-transcriptional gene regulation and enhances cell viability by downregulating specific transcripts in human cell lines.
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Tensile bond strength of CAD-CAM all ceramic crowns before and after thermomechanical aging.

J Prosthodont

December 2023

Department of Prosthodontics and Research Institute of Oral Science, College of Dentistry, Gangneung-Wonju National University, Gangneung, Republic of Korea.

Purpose: The purpose of this in vitro study was to compare the tensile bond strength (TBS) of resin nanoceramics (RNC), zirconia, and lithium disilicate (LS2) restorations cemented to titanium abutments before and after thermomechanical aging.

Materials And Methods: Twelve specimens per group were fabricated to determine the TBS between a titanium abutment and four types of crown materials (2 RNCs, LS2, and translucent zirconia crowns for the maxillary molar). After milling, the abutments and crowns were cemented with resin cement after air-particle abrasion.

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Redefining precision and efficiency in orthognathic surgery through virtual surgical planning and 3D printing: a narrative review.

Maxillofac Plast Reconstr Surg

December 2023

Department of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University, Gangneung, 28644, Republic of Korea.

Orthognathic surgery, essential for addressing jaw and facial skeletal irregularities, has historically relied on traditional surgical planning (TSP) involving a series of time-consuming steps including two-dimensional radiographs. The advent of virtual surgical planning (VSP) and 3D printing technologies has revolutionized this field, bringing unprecedented precision and customization to surgical processes. VSP facilitates 3D visualization of the surgical site, allowing for real-time adjustments and improving preoperative stress for patients by reducing planning time.

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Article Synopsis
  • A new ciliate species, Aspidisca koreana n. sp., was identified off the eastern coast of South Korea, with detailed studies on its morphology and molecular phylogeny.
  • The morphological features were characterized through observations of living cells and various staining techniques, revealing specific traits such as its small size and unique cirri arrangement.
  • Phylogenetic analysis using 18S rDNA sequences confirmed its classification as a distinct species, following the typical morphogenetic patterns of the genus.
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The living morphology, infraciliature, and molecular phylogeny of a new soil ciliate, Hemiurosomoida koreana n. sp., discovered in a sample collected from a mountain in the northeast of South Korea, were investigated.

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O- and N-Methyltransferases in benzylisoquinoline alkaloid producing plants.

Genes Genomics

March 2024

Department of Smart Farm and Agricultural Industry, Kangwon National University, Chuncheon, 24341, Republic of Korea.

Article Synopsis
  • Secondary metabolites like benzylisoquinoline alkaloids (BIA) have significant pharmacological potential, and methyltransferases (MTs) play a crucial role in modifying these compounds to enhance their properties.
  • Research involved isolating MTs from various BIA-producing plants and performing molecular and phylogenetic analyses to understand their roles better.
  • The study identified 42 O-methyltransferases and 8 N-methyltransferases, revealing their evolutionary relationships and potential for biotechnological applications in creating new therapeutic compounds.
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Phellinus linteus polysaccharides: A review on their preparation, structure-activity relationships, and drug delivery systems.

Int J Biol Macromol

February 2024

Department of Kinesiology, Nutrition, and Health, Miami University, Oxford, OH, United States of America.

Phellinus linteus polysaccharides exhibit antitumor, immunomodulatory, anti-inflammatory, and antioxidant properties, mitigate insulin resistance, and enhance the diversity and abundance of gut microbiota. However, the bioactivities of P. linteus polysaccharides vary owing to the complex structure, thereby, limiting their application.

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Background: Double-strand break repair protein (RAD50) gene plays important roles in genomic integrity, DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. The risk allele of RAD50 may negatively affect cancer by reducing the DNA repair capacity. Additionally, Sodium intake and Helicobacter pylori (H.

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