1,702 results match your criteria: "Gangneung Wonju National University[Affiliation]"

Article Synopsis
  • Understanding how parton mass and Casimir color factors affect heavy quark emissions is key to studying quantum chromodynamics (QCD).
  • This research presents the first experimental constraint on the charm-quark splitting function, obtained through measurements in proton-proton collisions at 13 TeV.
  • Findings indicate that charm quarks show a steeper splitting function compared to gluons and light quarks, experiencing fewer emissions with a lower likelihood of large-angle emissions.
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Crude polysaccharides were extracted from the white jellyfish () using water extraction and fractionated using ion-exchange chromatography to obtain three different fractions (JF1, JF2, and JF3). The chemical characteristics of four polysaccharides were investigated, along with their anti-inflammatory effect in LPS-stimulated RAW264.7 cells.

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Asthma is a chronic inflammatory disease involving structural changes to the respiratory system and severe immune responses mediated by allergic cytokines and pro-inflammatory mediators. (AC) is a kind of seaweed which contains a phlorotannin, trifuhalol A. To evaluate its anti-allergic inflammatory effect against asthma, an ovalbumin inhalation-induced mouse asthma model was used.

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CRISPR/Cas12a Collateral Cleavage Activity for Sensitive 3'-5' Exonuclease Assay.

Biosensors (Basel)

October 2023

Material & Component Convergence R&D Department, Korea Institute of Industrial Technology (KITECH), Ansan 15588, Republic of Korea.

This study presents a technique for detecting 3'-5' exonuclease activity through the use of CRISPR/Cas12a. These enzymes, including 3'-5' exonuclease (Exo III), perform crucial roles in various cellular processes and are associated with life expectancy. However, imbalances in their expression can increase susceptibility to diseases such as cancer, particularly under prolonged stress.

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Background: As a complex chronic metabolic disease, obesity not only affects the quality of human life but also increases the risk of various other diseases. Therefore, it is important to investigate the molecular mechanisms and therapeutic effects of dietary interventions that counteract obesity.

Results: In this study, we extracted soluble (SDF) and insoluble dietary fiber (IDF) from quinoa bran using an enzymatic method and further investigated their effects on lipid metabolism and blood lipid levels in obese rats.

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Despite the effectiveness and selectivity of natural enzymes, their instability has paved the way for developing nanozymes with high peroxidase activity using a straightforward technique, thereby expanding their potential for multifunctional applications. Herein, meso-copper-Prussian blue microcubes (Meso-Cu-PBMCs) nanozymes were successfully prepared via a cost-effective hydrothermal route. It was found that the Cu-PBMCs nanozymes, with three-dimensional (3D) mesoporous cubic morphologies, exhibited an excellent peroxidase-like property.

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Although older adults living alone are at a greater risk of solitary death, there is a dearth of literature in this area. Using the 2018 Seoul Elderly Survey, we investigated the extent to which older adults living alone in Seoul perceive the risk of solitary death and examined the association between the perceived risk of solitary death and depressive symptoms. Additionally, we explored the role of structural and functional support in that association as a buffering factor.

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Objective: : To investigate the long-term effects of 4-hexylresorcinol (4HR) on facial skeletal growth in growing male rats, with a focus on diabetic animal models.

Methods: : Forty male rats were used. Of them, type 1 diabetes mellitus was induced in 20 animals by administering 40 mg/kg streptozotocin (STZ), and they were assigned to either the STZ or 4HR-injected group (STZ/4HR group).

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Extracts from Dendropanax morbifera leaves ameliorates cerebral ischemia-induced hippocampal damage by reducing oxidative damage in gerbil.

J Stroke Cerebrovasc Dis

January 2024

Department of Anatomy and Cell Biology, College of Veterinary Medicine, and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Republic of Korea.

Article Synopsis
  • The study aimed to examine the neuroprotective effects of Dendropanax morbifera extract (DME) against ischemic damage in gerbils by administering different doses (100 or 300 mg/kg) over three weeks before inducing ischemia.
  • Results showed that only the higher dose (300 mg/kg) significantly improved memory impairments related to ischemia and preserved a substantial percentage of neurons in the CA1 region of the hippocampus.
  • Additionally, the 300 mg/kg DME treatment reduced morphological changes in glial cells and decreased oxidative stress indicators, thereby supporting its potential neuroprotective properties.
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Optimum postharvest storage conditions increase the postharvest quality and shelf life of horticultural crops. The effects of forced-air precooling (FAP) and modified atmosphere packaging (MAP) on shelf life, physicochemical quality, and health-promoting properties of bell pepper ( L. cv.

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Crustacean cardioactive peptide signaling system in the gastropod mollusk Pacific abalone.

Comp Biochem Physiol A Mol Integr Physiol

February 2024

Department of Marine Bioscience, Gangneung-Wonju National University, Gangneung, Gangwon-do, Republic of Korea. Electronic address:

Crustacean cardioactive peptide (CCAP) signaling systems have been characterized in a diverse range of protostomes, representatively in arthropods. The cyclic CXC-type CCAP regulates various biological activities through CCAP receptors (CCAPRs), which are orthologous to neuropeptide S receptors (NPSRs) in deuterostomes. However, the CCAPRs of the lophotrochozoa remain poorly characterized; therefore, the relationship between the CCAP, NPS, and CXC-type oxytocin/vasopressin (OT/VP) signaling systems is unclear.

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Objective: To compare changes in the maxillary posterior structure as seen in cone-beam computed tomography (CBCT) images resulting from facemask therapy using skeletal (miniplate/FM) anchorage versus tooth-borne anchorage (RME/FM).

Materials And Methods: A retrospective study was conducted on 20 patients divided into the miniplate/FM group (nine patients aged 9.5 ± 1.

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Article Synopsis
  • Fractionated lipids obtained from the tunic of Pyuridae exhibit anti-inflammatory properties and show immune-enhancing effects on macrophage cells.
  • The study tested various lipid fractions (neutral lipids, glycolipids, and phospholipids) on RAW264.7 cells to assess their impact on NO production, immune gene expression, and signaling pathways.
  • Results indicated that neutral lipids and glycolipids significantly boosted NO and PGE production while enhancing phagocytic activity and activating key immune signaling pathways, suggesting their potential as immune-enhancing agents.
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Cross-Referencing Self-Training Network for Sound Event Detection in Audio Mixtures.

IEEE Trans Multimedia

May 2022

Department of Electrical and Computer Engineering and jointly with the Department of Psychology and Brain Sciences, Johns Hopkins University, Baltimore, MD, 21218 USA.

Sound event detection is an important facet of audio tagging that aims to identify sounds of interest and define both the sound category and time boundaries for each sound event in a continuous recording. With advances in deep neural networks, there has been tremendous improvement in the performance of sound event detection systems, although at the expense of costly data collection and labeling efforts. In fact, current state-of-the-art methods employ supervised training methods that leverage large amounts of data samples and corresponding labels in order to facilitate identification of sound category and time stamps of events.

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Mg-incorporated sorbent for efficient removal of trace CO from H gas.

Nat Commun

November 2023

Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul, Republic of Korea.

Removal of trace CO impurities is an essential step in the utilization of Hydrogen as a clean energy source. While various solutions are currently employed to address this challenge, there is an urgent need to improve their efficiency. Here, we show that a bead-structured Mg, Cu, and Ce-based sorbent, MgCuCeO, demonstrates superior removal capacity of trace CO from H with high stability.

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This study addresses the propagation challenges faced by 'Shine Muscat', a newly introduced premium grapevine cultivar in South Korea, where multiple viral infections pose considerable economic loss. The primary objective was to establish a robust in vitro propagation method for producing disease-free grapes and to identify effective plant growth regulators to facilitate large-scale mass cultivation. After experimentation, 2.

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Remembering Prof. Il-Woo Nam: a pioneering surgeon and a compassionate mentor.

Maxillofac Plast Reconstr Surg

October 2023

Department of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University, Jibyun-Dong, Gangneung, Gangwondo, 28644, Republic of Korea.

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In this study, Cnidium officinale-derived polysaccharides were isolated and investigated for their immune enhancing and anticancer activities. The isolated crude and its fractions, such as F1 and F2, contain carbohydrates (51.3-63.

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In this study, we assessed spatial and temporal variations in the trophic structure of fish assemblages in the Yellow Sea during spring and summer 2022 and compared their isotopic niches between the Provisional Measure Zone (PMZ) and Korea's west areas (non-PMZ) within the Yellow Sea. Spatial and temporal differences in the diversity and dominant species of fish assemblages were found between the PMZ and non-PMZ areas between the seasons. The mean δC values of fish assemblages were relatively higher in the non-PMZ areas than in the PMZ areas.

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Mucoadhesive chitosan microcapsules for controlled gastrointestinal delivery and oral bioavailability enhancement of low molecular weight peptides.

J Control Release

January 2024

Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul 06351, Republic of Korea; Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University, Suwon 16419, Republic of Korea; School of Chemical Engineering, Sungkyunkwan University, Suwon 16419, Republic of Korea. Electronic address:

A bioactive compound, collagen peptide (CP), is widely used for biological activities such as anti-photoaging and antioxidant effects, with increased oral bioavailability because of its low molecular weight and high hydrophilicity. However, controlling release time and increasing retention time in the digestive tract for a more convenient oral administration is still a challenge. We developed CP-loaded chitosan (CS) microcapsules via strong and rapid ionic gelation using a highly negative phytic acid (PA) crosslinker.

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In this paper, we consider the Kelvin-Helmholtz instability in the magnetohydrodynamic flow. The motion of the interface is described by a current-vortex sheet. We examine the linear stability of the current-vortex sheet model and determine the growth rate of the interface.

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The purpose of this research was to systematically examine and collate evidence on couple-oriented interventions for mental health to identify trends in the literature, review research strategies, and suggest directions for future research. A systematic search included studies relating to couple-oriented interventions for preventing mental disorders and/or promoting mental health. We identified a total of 52 studies, which included 55 articles.

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Effects of prenatal bisphenol S and bisphenol F exposure on behavior of offspring mice.

Anim Cells Syst (Seoul)

October 2023

Department of Molecular Biology, College of Natural Sciences, Pusan National University, Busan, Republic of Korea.

Article Synopsis
  • - Bisphenol A (BPA) is known to disrupt hormones and is being replaced by alternatives like Bisphenol S (BPS) and Bisphenol F (BPF), which also exhibit similar endocrine-disrupting properties.
  • - A study was conducted where pregnant mice were exposed to BPS and BPF to assess their effects on neurobehavioral development in their offspring.
  • - Results indicated that while BPS and BPF did not impact behaviors related to anxiety, depression, locomotion, memory, or cognition, they did reduce the mice's preference for social interactions, suggesting an effect on social behaviors specifically.
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