Association between pre-diagnostic serum uric acid levels in patients with newly diagnosed epilepsy and conversion rate to drug-resistant epilepsy within 5 years: A common data model analysis.

Purpose: Drug-resistant epilepsy (DRE) poses a significant challenge in epilepsy management, and reliable biomarkers for identifying patients at risk of DRE are lacking. This study aimed to investigate the association between serum uric acid (UA) levels and the conversion rate to DRE.

Methods: A retrospective cohort study was conducted using a common data model database.

Association between impaired glucose metabolism and long-term prognosis at the time of diagnosis of depression: Impaired glucose metabolism as a promising biomarker proposed through a machine-learning approach.

Background: Predicting the course of depression is necessary for personalized treatment. Impaired glucose metabolism (IGM) was introduced as a promising depression biomarker, but no consensus was made. This study aimed to predict IGM at the time of depression diagnosis and examine the relationship between long-term prognosis and predicted results.

Diagnosis of Bleeding Meckel's Diverticulum in Adults.

Background And Aims: Various modalities have been used to diagnose Meckel's diverticulum (MD) in practice, but with their diagnostic accuracy deemed to be unsatisfactory for clinical practice. Moreover, the usefulness of these modalities has not been evaluated for the diagnosis of bleeding MD in adults, due to the relative rarity of this condition. Therefore, the aim of our multicenter study was to determine the most accurate modality for the preoperative diagnosis of bleeding MD in adults.

Prediabetes is associated with a high-risk colorectal adenoma.

Background: Type 2 diabetes mellitus is associated with an increased risk of colorectal neoplasia. However, association between prediabetes and colorectal adenoma has not been reported.

Aims: The aim of this study was to evaluate the relationship between prediabetes and the presence of colorectal adenomas.

Performance of the fecal immunochemical test is not decreased by high ambient temperature in the rapid return system.

Background: Hemoglobin concentration of fecal immunochemical test may be decreased at high ambient temperature, and fecal samples in FIT may be exposed to high ambient temperature.

Aims: The aim of this study was to determine whether a high ambient temperature on the day of screening may decrease the performance of FITs in population-based screening.

Methods: We performed FITs for asymptomatic participants aged 50 years or older.

Safety and cost-effectiveness of outpatient colonoscopic polypectomy.

Background/aims: Factors that increase the complications arising from colonoscopic polypectomy have been well studied; however, data regarding complications from outpatient polypectomy is limited. The aim of this study was to identify the safety and costeffectiveness of outpatient colonoscopic polypectomy.

Methodology: Consecutive series of 804 patients who underwent colonoscopic polypectomy for 1,446 polyps were analyzed.

May abnormal carotid intima-media thickness predict colorectal neoplasm?

Background/aims: Atherosclerosis was reported as a clinical indicator of colorectal neoplasm. However, a direct association between colorectal neoplasm and carotid intima-media thickness (IMT), a surrogate marker for atherosclerosis, has not been established. The aim of this study was to evaluate the association between abnormal carotid IMT and colorectal neoplasm.

Telephone reminder call in addition to mailing notification improved the acceptance rate of colonoscopy in patients with a positive fecal immunochemical test.

Background And Aims: Colorectal cancer (CRC) screening with a fecal immunochemical test (FIT) reduces CRC mortality; however, the acceptance rate of a colonoscopy in patients with a positive FIT was not high. The aim of this study was therefore to determine whether a telephone reminder call could increase the acceptance rate of colonoscopy in patients with a positive FIT.

Methods: We performed FITs for asymptomatic participants aged 50 years or older.