Exploring the anticancer potential and mechanisms of action of natural coumarins and isocoumarins.

Natural coumarins and isocoumarins show significant therapeutic potential against cancer in preclinical studies by targeting multiple pathways and processes. These compounds influence several critical cellular processes, such as apoptosis, autophagy, and cell cycle regulation, which are pivotal in cancer development and progression. Their capability to target multiple signalling pathways provides a strategic advantage over single-target therapies, which are often limited by drug resistance.

Synergistic effects of selenium nanoparticles and LED light on enhancement of secondary metabolites in sandalwood () plants through callus culturing technique.

The yield and concentration of secondary metabolites (SMs) in plants can vary due to numerous challenges such as dynamic environmental conditions, moisture, soil quality, soil organic matter and plant genetics. To obtain a good yield of SMs novel elicitation approaches, such as the use of biotic and abiotic stressors, genetic modifications, and optimized growth conditions, have been practiced, particularly the use of selenium nanoparticles (SeNPs) and light emitting diode (LED) interaction through employing tissue culture technique. In the present study, callus cultures of sandalwood ( L.

Silicon-Mediated Improvement in Drought and Salinity Stress Tolerance of Black Gram ( L.) by Modulating Growth, Physiological, Biochemical, and Root Attributes.

Water is a precious commodity for plant growth and metabolism; however, its scarcity and saline sand conditions have a drastic effect on plant growth and development. The main objective of the current study was to understand how silicon (Si) application might help Black gram ( L.) against the negative impacts of salt stress and drought.

Mechanisms of microbial resistance against cadmium - a review.

The escalating cadmium influx from industrial activities and anthropogenic sources has raised serious environmental concerns due to its toxic effects on ecosystems and human health. This review delves into the intricate mechanisms underlying microbial resistance to cadmium, shedding light on the multifaceted interplay between microorganisms and this hazardous heavy metal. Cadmium overexposure elicits severe health repercussions, including renal carcinoma, mucous membrane degradation, bone density loss, and kidney stone formation in humans.

Recent advances and mechanisms of microbial bioremediation of nickel from wastewater.

The global concern over emerging pollutants, characterized by their low concentrations and high toxicity, necessitates effective remediation strategies. Among these pollutants, pharmaceutical and personal care products, pesticides, surfactants, and persistent organic pollutants have gained significant attention. These contaminants are extensively distributed within aquatic ecosystems, posing threats to both human and aquatic physiological systems.

Antimicrobial and antioxidant activities of fennel oil.

It is of interest to estimate the effects of foliar spray (ISA) on essential oil yield, chemical constituents, antioxidant, and antimicrobial activities of fennel (Foeniculum vulgare Mill).Fennel was treated with ISA solutions at 40 and 80 mg L-1 doses. Application of ISA significantly augmented antioxidant and antimicrobial activities in addition to essential oil yield and its principal elements in fennel.

Analysing the role of gender and place of residence in acceptability and satisfaction towards e-learning among university students' during COVID-19 pandemic in India.

This paper has two broad objectives; the first is to examine the challenges of e-learning faced by the students keeping in view their place of residence and gender in India, particularly during the second-wave of Covid-19. The second objective is to examine the role of place of residence and gender of students in the acceptance and satisfaction towards e-learning. The data has been obtained through an online survey of the students of University of Jamia Millia Islamia, New Delhi, India, in which a total of 490 students participated.

Lead-induced modification of growth and yield of L. and its soil remediation potential.

This study was designed to evaluate the pre-reproductive and reproductive responses of L. (flax, linseed plant) to different levels of Pb in the soil. Flax seeds were sown in garden soil-filled earthen pots and treated with three different levels of lead as lead chloride (150, 450, and 750 mg Pb kg soil) except control, and each treatment was replicated three times.

Cellulose an ageless renewable green nanomaterial for medical applications: An overview of ionic liquids in extraction, separation and dissolution of cellulose.

Cellulose is a renewable natural fiber, which has gained enormous and significant research interest and evolved as the prime and promising candidate for replacing synthetic fibers. The various sources of cellulose, which is one of the world's most ubiquitous and renewable biopolymer resources, include trees, plants, tunicate and bacteria. The renewable biomaterial in the form of nanocellulose and its composites have been included in this review having the broad range of medical applications, viz.

Biogenic Synthesis, Characterization and Evaluation of Silver Nanoparticles from JX556221 Against Human Colon Cancer Cell Line HT-29.

Nanobiotechnology has emerged as a promising technology to develop new therapeutically active nanomaterials. The present study was aimed to biosynthesize AgNPs extracellularly using Aspergillus niger JX556221 fungal extract and to evaluate their anticancer potential against colon cancer cell line, HT-29. UV-visible spectral characterization of the synthesized AgNPs showed higher absorption peak at 440 nm wavelength.

Antimicrobial Properties of Plant Essential Oils against Human Pathogens and Their Mode of Action: An Updated Review.

A wide range of medicinal and aromatic plants (MAPs) have been explored for their essential oils in the past few decades. Essential oils are complex volatile compounds, synthesized naturally in different plant parts during the process of secondary metabolism. Essential oils have great potential in the field of biomedicine as they effectively destroy several bacterial, fungal, and viral pathogens.

Does seed size and surface anatomy play role in combating phytotoxicity of nanoparticles?

Rapid utilization of nano-based products will inevitably release nanoparticles into the environment with unidentified consequences. Plants, being an integral part of ecosystem play a vital role in the incorporation of nanoparticles in food chain and thus, need to be critically assessed. The present study assesses the comparative phytotoxicity of nanoparticle, bulk and ionic forms of zinc at different concentrations on selected plant species with varying seed size and surface anatomy.

Nitrate and Nitrogen Oxides: Sources, Health Effects and Their Remediation.

Increased use of nitrogenous (N) fertilizers in agriculture has significantly altered the global N-cycle because they release nitrogenous gases of environmental concerns. The emission of nitrous oxide (NO) contributes to the global greenhouse gas accumulation and the stratospheric ozone depletion. In addition, it causes nitrate leaching problem deteriorating ground water quality.

Control of Basal Stem Rot Disease in Oil Palm by Supplementation of Calcium, Copper, and Salicylic Acid.

Continuous supplementation of mineral nutrients and salicylic acid (SA) as foliar application could improve efficacy in controlling basal stem rot (BSR) disease in oil palm seedling. It is revealed from the results that the highest disease severity index (58.3%) was recorded in T8 treatments at 9 months after inoculation.

Molecular Breeding Strategy and Challenges Towards Improvement of Blast Disease Resistance in Rice Crop.

Rice is a staple and most important security food crop consumed by almost half of the world's population. More rice production is needed due to the rapid population growth in the world. Rice blast caused by the fungus, Magnaporthe oryzae is one of the most destructive diseases of this crop in different part of the world.