884 results match your criteria: "Gadjah mada University[Affiliation]"

Characterization of yellowfin tuna (Thunnus albacares) skin gelatin extracted by bromelain hydrolysis and ultrasound pre-treatment.

J Food Sci

December 2024

Department of Food and Agricultural Product Technology, Faculty of Agricultural Technology, Gadjah mada University, Yogyakarta, Indonesia.

Yellowfin tuna skin waste is a potential collagen source for gelatin through hydrolysis. Enzymatic hydrolysis is eco-friendly but expensive, necessitating efficiency improvements. Ultrasound pre-treatment enhances efficiency via cavitation effects.

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Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by hyperglycemia, insulin resistance, and decreased insulin secretion. With its rising global prevalence, effective management strategies are critical to reducing morbidity and mortality. This systematic review compares the efficacy, safety, and long-term outcomes of four major pharmacological treatments for T2DM: sodium-glucose cotransporter-2 (SGLT2) inhibitors, dipeptidyl peptidase-4 (DPP-4) inhibitors, metformin, and insulin.

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Background: Giant cell tumor of bone (GCTB) is a rare benign tumor that may also exhibit aggressive local behavior. Recurrence of GCTB is common even after complete resection. GCTB typically occurs in long bones, and only 2.

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Background: Post-mastectomy lymphedema is a common complication following breast cancer surgery, characterized by the accumulation of lymphatic fluid, causing swelling, discomfort, and functional limitations in the affected arm. Traditional treatments for lymphedema include manual lymphatic drainage and compression garments, but their effectiveness is variable, and many patients do not achieve satisfactory outcomes. Emerging therapeutic modalities such as Low-Level Laser Therapy (LLLT), Kinesio Taping, and Endermology offer potential non-invasive treatment alternatives.

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Objectives: This study aimed to investigate the physical properties of Indonesian local sheep skin collagen extracted by acid and enzymatic methods.

Materials And Methods: Collagen was isolated from Pure Breed Garut Sheep (.) skin, 1.

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Seeking consensus on physician leadership development in rural and remote Indonesian primary care settings: a Delphi study.

Leadersh Health Serv (Bradf Engl)

January 2025

Department of Educational Development and Research, Maastricht University, Maastricht, The Netherlands and Department of Pediatrics, Dr Horacio E Oduber Hospital, Oranjestad, Aruba.

Purpose: This study aims to formulate a consensus on primary care physicians' leadership competencies tailored to Indonesia's rural and remote health systems using the LEADS framework. Effective physician leaders are essential in these settings; however, many physicians lack the necessary leadership qualifications due to insufficient training. From a medical education perspective, this issue is further compounded by the lack of consensus on leadership course content.

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Background: Consumer awareness of food adulteration is increasing nowadays. Motivated by economic gain, unethical meat producers try to blend halal meat such as beef with non-halal meat like rat meat (RM).

Aim: This study aims to develop a real-time polymerase chain reaction (RT-PCR) analysis method to analyze the presence of RM in beef meatballs.

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Purpose: This research was conducted to explore the experience of mothers in raising stunted toddlers aged between 6-59 months. It also examined the perceptions of parenting styles shaped by socio-cultural contexts and time constraints affecting the nutritional status as well as growth in Bejiharjo Village, Java, Indonesia.

Methods: A qualitative method was used and data were collected through in-depth interviews, diary recording, and focus group discussions with mothers of toddlers, stakeholders, and healthcare professionals.

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A Case of CUP with Malignant Pleural Effusion: Overcoming Diagnostic and Therapeutic Hurdles with Chemotherapy.

Case Rep Oncol

October 2024

Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Public Health, and Nursing, Gadjah Mada University/Dr. Sardjito Hospital, Yogyakarta, Indonesia.

Introduction: Cancers of unknown primary (CUPs) present a diagnostic challenge as their origin is unidentified at diagnosis. Massive pleural effusion (MPE), indicative of lung metastasis in CUP, categorizes the condition into an unfavorable subset with a poor prognosis. Patients in this subset may exhibit a lower response to specific therapies.

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Article Synopsis
  • The study analyzed global, regional, and national trends in injury burden and identified risk factors contributing to injuries using data from the GBD 2019.
  • In 2019, there were approximately 713.9 million injury incidents and 4.3 million injury-related deaths globally, with low bone mineral density emerging as the leading risk factor.
  • The findings emphasize the need for effective global injury prevention policies by highlighting the persistent impact of injuries on global health.
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Background: Health information systems are critically important in disaster management. It supports disaster management activities and the information needed for decision-making support. We aimed to evaluate comprehensively published literature on disaster health information systems designed to identify and extract the required framework and components.

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Article Synopsis
  • The study investigated how global longitudinal strain (GLS) can predict left ventricle reverse remodeling (LVRR) in patients with severe chronic primary mitral regurgitation undergoing valve replacement surgery.
  • Using pre- and postsurgery echocardiography data from 103 patients, researchers found that GLS is an independent predictor of LVRR, with a specific threshold for effective measurement.
  • The results suggest GLS could serve as a useful tool for assessing patient outcomes and risks of mortality and morbidity after surgery.
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Analysis of the mental health of pharmacy students at A number of public and private universities in Indonesia.

Explor Res Clin Soc Pharm

December 2024

Department of Health Sciences, University Medical Center Groningen (UMCG), University of Groningen, Groningen, the Netherlands.

Background: This study examines the mental health of pharmacy students at various state and private universities in Indonesia, as well as the factors that influence it. The low mental health of pharmacy students can be found in a third of some countries. Similar findings occurred in the United States, France, and several Asian countries.

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Article Synopsis
  • The study evaluated the effectiveness of the Bebas Pasung program in Indonesia, which aimed to free individuals with severe mental illness from confinement (pasung) and provide them with mental health services after a policy was declared by the Ministry of Health in 2010.
  • Out of 114 individuals who were unlocked, 62 caregivers participated in a follow-up study, revealing that a quarter of those released had been re-locked, and many faced challenges in medication adherence and maintaining a stable quality of life.
  • The findings indicate that while the program successfully released and treated individuals, there is a need for better integration with community-based mental health services to ensure ongoing care and support for these individuals.
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Maleic anhydride esterified potato starch as the binder in silicon nanoparticles anode for lithium-ion batteries.

Int J Biol Macromol

November 2024

Advanced Materials Research Center (AMRC), Faculty of Engineering, Universitas Indonesia, Indonesia; Department of Metallurgical and Materials Engineering, Universitas Indonesia, Depok 16424, Indonesia.

Article Synopsis
  • Potato starch acts as a natural carbohydrate binder that promotes strong bonds with silicon particles, which is beneficial for lithium-ion battery performance.
  • Maleic anhydride modification of potato starch enhances its stability and effectiveness in these batteries, as indicated by various spectroscopy and analysis techniques.
  • The results show promising battery cycling performance with a capacity of 1950 mAh/g, alongside favorable structural changes observed in the modified starch.
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Article Synopsis
  • * Recent efforts to stop smoking haven't been put into action yet, and it’s important to see what could happen if smoking rates stay the same or improve.
  • * Researchers used models to predict health outcomes by 2050 based on different scenarios of smoking rates, showing that cutting smoking could greatly improve health and life expectancy.
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A boy with nonambulatory Duchenne muscular dystrophy (DMD) tested positive for exon 63 duplication and exhibited intellectual disability, overweight and dyslipidaemia. The patient underwent a comprehensive multidisciplinary approach involving pharmacological and non-pharmacological interventions. Despite challenges, such as socioeconomic constraints and limited access to advanced therapies, the patient received tailored care.

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Article Synopsis
  • Insomnia is more common in patients with type 2 diabetes mellitus (T2DM), contributing to low-grade inflammation and heightened risk for cardiovascular events and overall mortality.
  • This study aimed to investigate the impact of a spiritual-based therapy called Latihan Pasrah Diri (LPD) on sleep quality and inflammation in T2DM patients who do not suffer from depression.
  • Results showed that participants in the LPD group experienced significant improvements in sleep quality and reductions in specific inflammatory markers compared to those receiving standard diabetes care alone.
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Article Synopsis
  • - The study investigates the roles of circulating mRNAs (VEGF, PTEN, and SOCS1) in the progression of nasopharyngeal carcinoma (NPC) to better understand its molecular mechanisms and identify potential biomarkers for the disease.
  • - Researchers analyzed blood samples from 160 NPC patients and 80 controls, finding higher levels of VEGF and SOCS1 mRNAs in advanced stages of NPC, while PTEN mRNA was significantly decreased.
  • - The results suggest that changes in these mRNAs are linked to NPC progression and could be useful as biomarkers, though further research is needed to confirm their effectiveness in predicting outcomes for NPC patients.
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Article Synopsis
  • The roasting process of sesame oil changes its internal composition, which affects its stability against oxidation, but this effect varies depending on the type of oxidation (thermal or photo).
  • The study compared different sesame oils (raw, refined, and roasted) and rapeseed oils by exposing them to thermal oxidation at 120℃ and photo-oxidation at 50,000 lx for 5 and 10 hours.
  • The findings indicate that roasted sesame oil is more stable during thermal oxidation due to antioxidant changes, while refined sesame oil is more stable under photo-oxidation, highlighting the significant impact of both roasting and refining processes on sesame oil’s oxidative stability.
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  • * Out of 155 examined cows, 61.9% showed reproductive issues due to FMD, with the most common problem being ovarian hypofunction (53.5%).
  • * Administering gonadotropin hormone-releasing hormone (GnRH) to affected cows resulted in a 98% recovery rate in reproductive performance, with improved conception and pregnancy rates.
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Article Synopsis
  • Researchers studied strokes from 1990 to 2021 to understand how many people get them and how they are affected around the world.
  • In 2021, strokes caused about 7.3 million deaths and were a major cause of health problems, especially in specific regions like Southeast Asia and Oceania.
  • There are differences in stroke risks based on where people live and their age, and some areas actually saw more strokes happening since 2015.
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Food poisoning is a major concern in catering services in Indonesia, with multiple outbreaks being reported in factories and offices. This study aimed to assess the level of food safety knowledge, personal hygiene practices, and microbiological quality of chicken and egg dishes at three catering companies in the Yogyakarta Special Region of Indonesia, which provide mass catering for workers. From March to July 2019, a cross-sectional study was conducted using validated questionnaires, observation checklists, and microbiological tests to measure the parameters of and .

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Article Synopsis
  • Despite improvements in diabetes care, new treatments are needed to effectively stop the worsening of diabetic kidney disease (DN-DKD), highlighting the significance of endothelin-1 in this condition.
  • Endothelin-1 contributes to kidney damage by promoting cell proliferation and causing injury to podocytes, with receptor antagonists like atrasentan showing promise in protecting the kidneys by lowering protein levels and damage.
  • The review discusses how these new drugs could potentially slow down cDN-DKD's progression while considering possible side effects, like fluid retention and heart failure, and the importance of combining them with current standard treatments.
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