Utility of colposcopy for the screening and management of cervical cancer in Africa: a cross-sectional analysis of providers' training and practices.

Introduction: Cervical cancer is a public health issue in Africa with devastating socioeconomic consequences due to the lack of organized screening programs. The success of screening programs depends on the appropriate investigation and management of women who test positive for screening. Colposcopic assessment following positive screening results is a noteworthy issue in Africa.

Phytochemical Analysis and Antidiarrheal Activity of Stem Bark Decoctions of Sabine (Clusiaceae).

is a medicinal plant of which bark decoctions are used in traditional medicine for the treatment of diarrhea symptoms in Gabon. The aim of the present work was to perform phytochemical and pharmacological analyses of decoctions of bark. In a principal approach, spectrophotometric analyses were used to quantify phenolic compounds, followed by liquid chromatography coupled to mass spectrometry analysis that allowed the identification of flavanone-flavone dimers as the main metabolites.

Architecting an enterprise financial management model: leveraging multi-head attention mechanism-transformer for user information transformation.

Financial management assumes a pivotal role as a fundamental information system contributing to enterprise development. Nonetheless, prevalent methodologies frequently encounter challenges in proficiently overseeing diverse information streams inherent to financial management. This study introduces an innovative paradigm for enterprise financial management centered on the transformation of user information signals.

Plasmodium knowlesi Infection Is Associated With Elevated Circulating Biomarkers of Brain Injury and Endothelial Activation.

Background: Malaria remains a major public health concern with substantial morbidity and mortality worldwide. In Malaysia, the emergence of Plasmodium knowlesi has led to a surge in zoonotic malaria cases and deaths in recent years. Signs of cerebral involvement have been observed in a noncomatose, fatal case of knowlesi infection, but the potential impact of this malaria species on the brain remains unexplored.

The Influence of Age, Sex, and Season on Hematological Parameters in a Captive Population of Former Laboratory Chimpanzees (Pan troglodytes).

This study aimed to establish a baseline hematological profile and examine the influence of age, sex, and season on hematological parameters in captive chimpanzees (Pan troglodytes) living in a humid tropical climate. Hematological parameters are a useful tool for assessing health status and diagnosing diseases in animals. We analyzed 473 blood samples collected from 84 chimpanzees (43 females and 41 males) during annual health checks, conducted under anesthesia for a routine physical examination.

Scratching the surface of Afrotropical Dissomphalus (Hymenoptera, Bethylidae): a revision uncovering 114 new species.

The main goal of this paper is to revise the Dissomphalus genus within the Afrotropical region. Specimens were collected across seventeen countries: Benin, Botswana, Cameroon, Central African Republic, Democratic Republic of Congo, Gabon, Guinea, Kenya, Mozambique, Namibia, Nigeria, Rwanda, South Africa, Tanzania, Uganda, Zambia and Zimbabwe. A total of 127 species have been identified in the Afrotropical region.

New records, diagnostics and preliminary checklist of the superfamily Pentatomoidea (Hemiptera: Heteroptera) from the Comoro Islands.

The following species are recorded from the Comoro Islands for the first time: 12 species of Pentatomidae: Pentatominae-Anoano pronotalis Cachan, 1952 (from Mayotte), Antestiopsis clymeneis cf. galtiei (Frappa, 1934) (Mayotte), Bagrada hilaris (Burmeister, 1835) (Mayotte), Bathycoelia rodhaini Schouteden, 1913 (Mayotte), Coquerelia ventralis Horváth, 1904 (Mayotte), Eurysaspis transversalis Signoret, 1851 (Anjouan, Grande Comore, Mayotte), Gadarscama ebenaui Reuter, 1887 (Anjouan, Grande Comore, Mohéli, Mayotte), Lerida annulicornis (Signoret, 1861) (Anjouan, Mayotte), Neoacrosternum validum (Horváth, 1904) (Grand Comore, Mayotte), Nezara viridula (Linnaeus, 1758) (Mayotte), Piezodorus hybneri (Gmelin, 1790) (Mayotte), and Stenozygum mirabile (Signoret, 1861) (Mayotte); two species of Plataspidae-Brachyplatys hemisphaerica (Westwood, 1837) (Mayotte) and Coptosoma maculatum Westwood, 1837 (Mayotte); and one species of Scutelleridae-Hotea denticulata Stål, 1865 (Mayotte). The endemic pentatomine species Bathycoelia cuneifera Bergroth, 1893, syn.

World Health Organization African Region national heads of units of diagnostics and laboratory services meetings proceedings.

Background: In the World Health Organization (WHO) African Region, many cases of serious and preventable diseases remain unmanaged because appropriate and good quality diagnostic support is not available at all levels within countries' health systems. Diagnostic and laboratory services influence the efficiency and effectiveness of both clinical and public health functions, including diagnosis, treatment, health promotion, disease prevention, surveillance and response, and research. Essential to global health security, these services are vital to decision-making processes by clinicians, epidemiologists, public health specialists, and health policymakers.

Homophily in social and demographic traits predict association patterns in female western and mountain gorillas.

Affiliative relationships are a hallmark of social relationships in gregarious mammals, but what drives variation of association patterns when kin are absent remains unknown. Gorillas, where females may disperse multiple times in their lives, provide an interesting counterpoint to female philopatric species to examine the factors influencing variation in association patterns. We examined demographic and social factors that may predict association patterns of female western (; Loango, Gabon) and mountain gorillas (; Bwindi, Uganda).

2025 Roadmap on 3D Nano-magnetism.

The transition from planar (2D) to three-dimensional (3D) magnetic nanostructures represents a significant advancement in both fundamental research and practical applications, offering vast potential for next-generation technologies like ultrahigh-density storage, memory, logic, and neuromorphic computing. Despite being a relatively new field, the emergence of 3D nanomagnetism presents numerous opportunities for innovation, prompting the creation of a comprehensive roadmap by leading international researchers. This roadmap aims to facilitate collaboration and interdisciplinary dialogue to address challenges in materials science, physics, engineering, and computing.

Multicomponent syntheses enable the discovery of novel quisinostat-derived chemotypes as histone deacetylase inhibitors.

In this study, we synthesized and evaluated novel histone deacetylase (HDAC) inhibitors derived from the clinical candidate quisinostat. A library of 16 compounds categorized in three novel chemotypes was rapidly generated using multicomponent reactions (MCRs), enabling efficient structure-activity relationship studies. First, the compounds were evaluated for their activity against the Plasmodium falciparum strains 3D7 and Dd2, the main malaria-causing parasite, identifying compound 18b of the type C series as the most potent.

Serological evidence of natural exposure to rabies in rural populations in Gabon.

Rabies is one of the oldest known zoonotic diseases, with dogs being the main reservoir for 99% of the cases of human rabies. However, wild animals may also be rabies vectors. In most cases, contact with a rabid animal results in rabies without pre- or post-exposure prophylaxis, and the disease is nearly always fatal.

Cancer in the Grand Libreville, Gabon (2013-2017).

Background: The burden of cancer is expected to nearly double in sub-Saharan Africa over the next 20 years. In Gabon, the primary population-based cancer registry to be established is located in the Grand Libreville. This study presents cancer incidence rates covering the first 5-year period of registration in this region.

Identification of complex Plasmodium falciparum genetic backgrounds circulating in Africa: a multicountry genomic epidemiology analysis.

Background: The population structure of the malaria parasite Plasmodium falciparum can reveal underlying adaptive evolutionary processes. Selective pressures to maintain complex genetic backgrounds can encourage inbreeding, producing distinct parasite clusters identifiable by population structure analyses.

Methods: We analysed population structure in 3783 P falciparum genomes from 21 countries across Africa, provided by the MalariaGEN Pf7 dataset.