80 results match your criteria: "GSL Dental College[Affiliation]"

Introduction: The study aims to investigate the antifungal efficacy of albedo extract of Punica grantum on candida albicans by evaluating the inhibitory capacity of alcoholic albedo extracts by disc diffusion method and by comparing the antifungal efficacy of alcoholic extract of albedo with clotrimazole and ethanol.

Methods: Using a conventional disc diffusion method, the effectiveness of Punica Granatum albedo extract against Candida albicans was assessed and evaluated depending on the presence or absence of inhibition zones, as well as the average diameter of inhibition zones. Albedo extract of Punica granatum serial dilutions were prepared ranging from 1%, 5%, 10%, 15%, 20% and 25% and its antifungal efficacy was tested against Candida albicans in comparison with clotrimazole and ethanol.

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Objective: The purpose of this investigation was to assess the effectiveness of various gutta-percha retrieval methods in endodontic retreatment.

Methods: Five groups were randomly allocated to extract human teeth that had already had root canal therapy: manual files, rotary tools, heat, solvents, and ultrasonics. By evaluating the amount of filling material still present, gutta-percha clearance was quantitatively examined, and root canal cleanliness was qualitatively appraised.

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Evaluation of Antimicrobial Efficacy of Etidronic Acid against in Primary Teeth: An Study.

Int J Clin Pediatr Dent

April 2024

Department of Pediatric and Preventive Dentistry, GSL Dental College and Hospital, Rajamahendravaram, Andhra Pradesh, India.

Background: In pulpectomy, to remove the inflamed or diseased pulp tissues and smear layer, the root canal is disinfected with mechanical instrumentation and copious irrigation.

Aim: The purpose of this present study is to evaluate the antibacterial efficacy of etidronic acid as an irrigant in primary teeth.

Materials And Methods: A total of 60 necrotic primary teeth in children aged 3-8 years were included.

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Introduction Fixed prosthodontic treatment involves the replacement of missing tooth structures with a variety of materials. Several newer metal-free ceramics have been developed in recent years to meet patients' aesthetic needs. The long-term performance of all ceramics, however, is unknown, necessitating a continuous evaluation of the materials' strength.

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Periodontitis and oral squamous cell carcinoma (OSCC) are prevalent oral diseases with distinct etiologies, yet they share certain molecular and biological characteristics. Gene expression datasets from the gene expression omnibus (GEO) repository (GSE30784 for OSCC and GSE10334 for periodontitis) were analyzed. Data preprocessing and differential gene expression analysis using GEO2R identified common differentially expressed genes (DEGs), and FunRich software facilitated the construction of a protein-protein interaction (PPI) network on the STRING database.

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Immunohistochemical evaluation of Glut1 in dentigerous cysts, odontogenic keratocysts, and ameloblastoma.

J Oral Maxillofac Pathol

April 2024

Department of Oral and Maxillofacial Pathology, GSL Dental College, Rajahmundry, Andhra Pradesh, India.

Context: Glucose uptake may be considered the rate-limiting step for the growth and metabolism of the cancer cell. Studies on GLUT1 have shown that GLUT1 is involved in cell survival and proliferation in both healthy and pathological circumstances. GLUT1 expression is regarded as one of the crucial elements in the development of local aggressiveness, tumour invasiveness, and metastasis, particularly in malignant tumours.

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Evaluation of the 3D Technology in the Auto-transplantation: An Original Research.

J Pharm Bioallied Sci

February 2024

Department of Oral and Maxillofacial Surgery, Narsinhbhai Patel Dental College and Hospital, Sankalchand Patel University, Visnagar, Gujarat, India.

Introduction: Using three-dimensional printed duplicates of the donor teeth, three-dimensional auto-transplantation is a medical procedure that moves a tooth from one location inside a patient to another. The intraoperative practicability during 3D auto-transplantation of teeth was evaluated in the present study.

Material And Methods: A prospective multicenter clinical study was done among the subjects.

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Background: Almost 70% of women residing in urban areas and 48% of women in rural areas use sanitary napkins in India. According to menstrual health alliance India (MHAI), single sanitary pad will take about 500-800 years to decompose as the plastic used in manufacturing is nonbiodegradable and causes severe noxious effects contributing to global warming through the production of planet warming fuels which eventually have severe impact on environment sustainability. Hence, the study was undertaken to contribute the evidence for the "Clean and Green India".

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Background Adenoid cystic carcinoma (ACC) poses clinical challenges with its unique histology and potential for perineural invasion, recurrence, and distant metastases. Recent genomic advancements have unveiled key genetic alterations in ACC, offering insights into its pathogenesis. Aim This study aims to unravel the intricate molecular landscape of ACC through a comprehensive analysis of gene expression patterns.

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Rationale: Ameloblastic carcinoma is defined as an ameloblastoma in which there is histological evidence of malignancy in primary tumour or recurrent tumour regardless if it has metastasised or not. It is aggressive in nature.

Patient Concerns: The patient presented with a painful swelling associated with restricted mouth opening.

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Article Synopsis
  • Heat shock proteins (HSPs), particularly HSP70, are linked to tumor growth and immune evasion in various cancers, and this study aimed to assess HSP70 as a potential predictor of malignant transformation in oral epithelial dysplasia.* -
  • The research involved analyzing 60 tissue samples, including different grades of dysplasia and normal tissues, for HSP70 expression through immunohistochemistry and statistical methods.* -
  • Results indicated that HSP70 expression increases with the severity of dysplasia and is significantly higher in established carcinoma, suggesting HSP70 may have prognostic value, although further studies with larger sample sizes are necessary for validation.*
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Introduction: There is a notable shift in the attitude of the admission, review, diagnostics, and follow-up of patients for all the medical sectors and of particular interest of cancer patients. The present study aimed to elaborate on the identification of patients with head and neck cancers (HNCs); the diagnostics, the triage, and the best treatment plan were all evaluated and at the same time compared with the years before the pandemic at a tertiary care center that caters to various other patients also.

Materials And Methods: A retrospective observational clinical study was conducted at the tertiary care center that catered to all the medical specialties.

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Fracture Resistance of Different Post-Core Systems: An Study.

J Pharm Bioallied Sci

July 2023

Department of Conservative Dentistry and Endodontics, GSL Dental College and Hospital, Rajhamundry, Andhra Pradesh, India.

Reasons for the failed endodontic teeth which had an extensive restoration can be attributed to the multiple materials that were used in it. Various post-core materials that are commonly used are compared for fracture resistance in the current study. Fourty maxillary incisors that needed root canal therapy were allocated into four groups of 10 each.

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Effectiveness of Removal of Hard Tissue Debris from the Mesial Root Canal System of Mandibular Molars using Different Supplementary Irrigation Protocols: An Original Study.

J Pharm Bioallied Sci

July 2023

Center for Transdisciplinary Research, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.

Introduction: An instrumented and endodontically treated tooth may sometimes impede disinfection by trapping hard tissue as well as the other canal contents at the isthmus level of the canal. Thus, the current study was piloted to assess the competence of two irrigating systems.

Methods: Twenty mandibular with two mesial canals convergent into a single foramen and joined by an isthmus of the human permanent teeth were compared for the two irrigation systems of continuous and intermittent ultrasonic (US) motions of the irrigation.

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Aim: To evaluate the efficiency of debris removal from the mesial root canals and isthmus of mesial roots of mandibular molars after final irrigant agitation with XP-endo Shaper, EndoVac (EV), plastic finishing file, and conventional needle irrigation.

Methods And Materials: Forty extracted human mandibular first molar teeth with the isthmus between the mesial roots were selected, access cavities were prepared and distal roots were decoronated. All the mesial root specimens were mounted in acrylic, sectioned at the coronal, middle, and apical thirds, along with the resin block, and examined for debris in the canals and isthmus before the start of the procedure using a stereomicroscope and were mounted back in a custom-made jig.

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Aim And Objective: The objective of this study was to assess and compare the dimensions (width (W), height (H), and length (L)) of the tuberosity distal to maxillary permanent second molar in individuals with skeletal and dental Class I and Class II malocclusions who had maxillary third molar agenesis.

Methodology: Cone beam computed tomography (CBCT) was used to measure the left (L) and right (R) anatomical tuberosity dimensions in three dimensions using the WillMaster software (HDX WILL Corporation, Korea). The measurements were compared between Class I (n = 35) and Class II (n = 35) normo-hypodivergent adult subjects.

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Aim and objectives The aim of this in-vitro study is to evaluate and compare the effect of various mouth rinsing agents on frictional resistance through sliding mechanics among orthodontic metal brackets and stainless steel (SS) archwire. Materials and methods Each group comprised 15 samples of maxillary first premolar pre-adjusted edgewise SS movable, un-bonded brackets (Koden Inc., United States) which were welded with a power arm, where 100 g of the load was suspended.

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Aim And Objectives: This study aims to determine the effect on shear bond strength (SBS) and adhesive remnant score between two color change adhesives (CCAs) with reduced curing time using different high-intensity light emitting diode (LED) units.

Materials And Methods: A total of 108 human first maxillary premolar teeth were randomly allocated into three principal groups (n = 36) based on the type of adhesives used. The adhesives include two CCAs: TransbondPlus Color Change Adhesive (3M, St.

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Aim And Objectives: To determine the impact on the mechanical properties and surface features of ceramic-coated nickel-titanium (CC-Ni-Ti) archwires when subjected to charcoal, probiotic, and chlorhexidine mouthwashes in in vitro conditions.

Materials And Methods: Eighty samples of 25 mm were cut from the posterior end of preformed maxillary 0.016'' CC-Ni-Ti super elastic archwires (Koden Company, USA) and distributed into four equal groups.

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Aims And Objectives: To determine the impact on the mechanical properties and surface characteristics of prefabricated 0.016" copper-nickel-titanium (Cu-Ni-Ti) type 35C (Ormco Company, USA) archwires when subjected to 0.05% sodium fluoride (NaF) mouthwash (ACT Anti-Cavity Fluoride Mouthwash, Sanofi Company, USA) and ozone-infused oil-pulling solution with coconut oil (O) (O Essentials, Health Ranger Store, USA).

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Background: The success of pulpectomy depends on complete eradication of microbial load by cleaning and shaping the primary root canals that is difficult to achieve because of anatomical intricacy of primary pulp dentin complex. Numerous instruments were tried, however, they proved to be inadequate. Selfadjusting file (SAF) is a newer file system that facilitates less dentin removal with maximal cleansing of root canals.

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Aim And Objectives: This study aims to evaluate the curing time minimally required for bonding stainless-steel (SS) brackets using a high-power light-emitting diode (LED) light curing unit (LCU) and examine the debonded enamel surface for adhesive remnant.

Materials And Methods: Based on the LED LCU and curing time employed, 80 human maxillary first premolar teeth were equally segregated into four groups. Three groups were cured using a high-power LED unit (Guilin Woodpecker Medical Instrument Co.

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Introduction: Oral squamous cell carcinoma (OSCC) is one of the most formidable health problems for mankind. These carcinomas are characterized by invasion of epithelial tumor cells into the stroma, which get embedded in extracellular matrix and collagen producing reactive changes. Such changes in the stroma may alter the biological aggressiveness of the tumor.

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Background & Objectives: Because of the inflammatory response to human immunodeficiency virus (HIV) infection and periodontitis risk of developing adverse pregnancy outcomes are high. There is a limited number of studies available in the literature regarding the association between periodontitis and adverse pregnancy outcomes, especially in HIV infection. So the main objective of the present study was to assess the risk of preterm low birth weight (PTLBW) associated with periodontitis among HIV seropositive pregnant women.

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Management of Alveolar Cleft Defect by Iliac Crest Secondary Bone Grafting: A Case Report.

Int J Clin Pediatr Dent

January 2022

Department of Oral & Maxillofacial Surgery, GSL Dental College, Rajamahendravaram, Andhra Pradesh, India.

Aim And Objective: This case report aims to describe the management of alveolar cleft defect by iliac crest secondary bone grafting.

Background: The secondary alveolar bone grafting performed during the mixed dentition period is an essential module of modern-day rehabilitation of cleft lip and palate patients with alveolar defects. Iliac crest bone graft is a frequent secondary graft used and is technique sensitive.

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