1 results match your criteria: "GSF Research Center Institute of Mammalian Genetics[Affiliation]"
In situ gene expression analysis during BMP2-induced ectopic bone formation in mice shows simultaneous endochondral and intramembranous ossification.
Growth Factors
December 2002
GSF Research Center Institute of Mammalian Genetics, Ingolstädter Landrtr. 1, D-85764 Neuherberg, Germany.
Article Synopsis
- The study investigated how ectopic bone forms in mice's muscles when treated with rhBMP2 and collagen type I.
- Researchers used mRNA in situ hybridization to compare gene expressions between normal bone formation and BMP2-induced bone growth.
- Findings indicated that key molecules regulating embryonic bone development are also present during ectopic bone formation, supporting the idea that both endochondral and intramembranous ossification occur simultaneously in this process.