2 results match your criteria: "GSF National Research Centre of Environment and Health[Affiliation]"

The fear of malevolent use of variola virus by terrorists has led to the implementation of a health care worker vaccination program and to the consideration of vaccination for the general public. However, due to concerns about side effects of the classical smallpox vaccine, especially for immunocompromised individuals, a safer vaccine is urgently needed. We characterized the immunogenicity of modified vaccinia virus Ankara (MVA), one of the more promising alternative smallpox vaccines, in a cohort of 10 chronically HIV-1-infected individuals undergoing highly active antiretroviral therapy (HAART).

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Article Synopsis
  • The study aimed to investigate the relationship between the G38S variant in the KCNE1 gene and QT interval prolongation, which can lead to increased risk of sudden death.
  • Researchers analyzed a group of 3,966 individuals from central Europe, finding no significant association between the G38S variant and QT interval in the overall sample or by gender.
  • The conclusion suggests that, unlike another known variant, G38S may not significantly affect QT intervals, but its potential impact in different ethnic groups or under specific conditions can't be entirely dismissed.
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