Automatic generation of knee kinematic models from medical imaging.

Background And Objective: Three-dimensional spatial mechanisms have been used to accurately predict passive knee kinematics, and have shown potential to be used in optimized multibody kinematic models. Such multi-body models are anatomically consistent and can accurately predict passive knee kinematics, but require extensive medical image processing and thus are not widely adopted. This study aimed to automate the generation of kinematic models of tibiofemoral (TFJ) and patellofemoral (PFJ) joints from segmented magnetic resonance imaging (MRI) and compare them against a corresponding manual pipeline.

Photocatalytic performance, anti-bacterial activities and 3-chlorophenol sensor fabrication using MnAlO·ZnAlO nanomaterials.

A MnAlO·ZnAlO nanomaterial was synthesized by co-precipitation and characterized by XRD, SEM, EDS, TEM, AFM, FTIR, PL, CV and EIS. The photocatalytic activity of the nanocomposite against MV dye and its MDR anti-bacterial functions were studied. The nanocomposite shows excellent photocatalytic as well as anti-bacterial activity.

Benchmarking hospital safety and identifying determinants of hospital-acquired complication: the case of Queensland cardiac linkage longitudinal cohort.

Background: Hospital-acquired complications (HACs) are costly and associated with adverse health outcomes, although they can be avoided. Administrative linkage health data have become more accessible and can be used to monitor and reduce HAC.

Aims: This study aims to use linkage administrative data to benchmark the safety performance of hospitals and estimate the feasible magnitude that HAC can be reduced.

Development and initial psychometric testing of the Intrahospital Transport Safety Scale in intensive care.

Objective: To develop and evaluate the psychometric properties of a scale measuring patient safety during the intrahospital transport process for intensive care.

Design: The scale was developed based on a theoretical model of the work system and patient safety, and items generated from participant observations. A Delphi study with international experts was used to establish content validity.

Photocatalysis, photoinduced enhanced anti-bacterial functions and development of a selective -tolyl hydrazine sensor based on mixed Ag·NiMnO nanomaterials.

In this work, a tri-metal based nanocomposite was synthesized and characterized. A detailed investigation of the photocatalytic dye degradation efficiency of the nanocomposite under visible light showed promising results in a wide pH range, both acidic and basic medium. Studies on anti-bacterial activity against seven pathogenic bacteria, including both Gram positive and Gram negative species, were conducted in the presence and absence of light and compared with the standard antibiotic gentamicin.

Enhanced photocatalytic activity and ultra-sensitive benzaldehyde sensing performance of a SnO·ZnO·TiO nanomaterial.

The synthesis of a ternary SnO·ZnO·TiO nanomaterial (NM) by a simple co-precipitation method and its potential applications as an efficient photocatalyst and chemical sensor have been reported. The synthesized nanomaterial was fully characterized by XRD, SEM, EDS, XPS, FTIR, AFM and photoluminescence studies. This nanomaterial exhibited enhanced efficiency in photo-catalysis of Methyl Violet 6b (MV) dye degradation.

What factors influence ward nurses' recognition of and response to patient deterioration? An integrative review of the literature.

Aim: In this integrative review, we aimed to: first, identify and summarize published studies relating to ward nurses' recognition of and response to patient deterioration; second, to critically evaluate studies that described or appraised the practice of ward nurses in recognizing and responding to patient deterioration; and third, identify gaps in the literature for further research.

Design: An integrative review.

Methods: The Cumulative Index to Nursing and Allied Health Literature (CINAHL) Ovid Medline, Informit and Google Scholar databases were accessed for the years 1990-2014.

Genetic variants are major determinants of CSF antibody levels in multiple sclerosis.

Immunological hallmarks of multiple sclerosis include the production of antibodies in the central nervous system, expressed as presence of oligoclonal bands and/or an increased immunoglobulin G index-the level of immunoglobulin G in the cerebrospinal fluid compared to serum. However, the underlying differences between oligoclonal band-positive and -negative patients with multiple sclerosis and reasons for variability in immunoglobulin G index are not known. To identify genetic factors influencing the variation in the antibody levels in the cerebrospinal fluid in multiple sclerosis, we have performed a genome-wide association screen in patients collected from nine countries for two traits, presence or absence of oligoclonal bands (n = 3026) and immunoglobulin G index levels (n = 938), followed by a replication in 3891 additional patients.

Studies on the pathophysiology and genetic basis of migraine.

Migraine is a neurological disorder that affects the central nervous system causing painful attacks of headache. A genetic vulnerability and exposure to environmental triggers can influence the migraine phenotype. Migraine interferes in many facets of people's daily life including employment commitments and their ability to look after their families resulting in a reduced quality of life.

The biology of the glutamatergic system and potential role in migraine.

Migraine is a common genetically linked neurovascular disorder. Approximately ∼12% of the Caucasian population are affected including 18% of adult women and 6% of adult men (1, 2). A notable female bias is observed in migraine prevalence studies with females affected ∼3 times more than males and is credited to differences in hormone levels arising from reproductive achievements.

Investigation of lymphotoxin α genetic variants in migraine.

Migraine is a common neurological disease with a genetic basis affecting approximately 12% of the population. Pain during a migraine attack is associated with activation of the trigeminal nerve system, which carries pain signals from the meninges and the blood vessels infusing the meninges to the trigeminal nucleus in the brain stem. The release of inflammatory mediators following cortical spreading depression (CSD) may further promote and sustain the activation and sensitization of meningeal nociceptors, inducing the persistent throbbing headache characterised in migraine.

Photocatalytic synthesis of TiO(2) and reduced graphene oxide nanocomposite for lithium ion battery.

In this work, we synthesized graphene oxide (GO) using the improved Hummers' oxidation method. TiO2 nanoparticles can be anchored on the GO sheets via the abundant oxygen-containing functional groups such as epoxy, hydroxyl, carbonyl, and carboxyl groups on the GO sheets. Using the TiO2 photocatalyst, the GO was photocatalytically reduced under UV illumination, leading to the production of TiO2-reduced graphene oxide (TiO2-RGO) nanocomposite.

Women's global self-determination, eating regulation, and body dissatisfaction: exploring the role of autonomy support.

Body dissatisfaction is an important correlate of dysfunctional eating. In the present study (N=208) the primary aim was to test whether women's internal and autonomous motivation can protect against endorsements of societal pressures regarding the ideal female body and against body dissatisfaction. Additionally, the role of others' autonomy support was investigated.

Photoelectrochemical characterization of a robust TiO2/BDD heterojunction electrode for sensing application in aqueous solutions.

Titanium dioxide (TiO(2)) and boron-doped diamond (BDD) are two of the most popular functional materials in recent years. In this work, TiO(2) nanoparticles were immobilized onto the BDD electrodes by a dip-coating technique. Continuous and uniform mixed-phase (anatase and rutile) and pure-anatase TiO(2)/BDD electrodes were obtained after calcination processes at 700 and 450 degrees C, respectively.