Am J Physiol Heart Circ Physiol
September 2016
Centre for Heart, Lung and Vascular Health, School of Health and Exercise Sciences, University of British Columbia-Okanagan, Kelowna, British Columbia, Canada; International Collaboration on Repair Discoveries, University of British Columbia, Vancouver, Canada; Department of Medicine, Division of Physical Medicine and Rehabilitation, University of British Columbia, Vancouver, Canada; and GF Strong Rehabilitation Centre, Vancouver Health Authority, Vancouver, Canada.
J Neurotrauma
February 2017
1 International Collaboration on Repair Discoveries (ICORD), University of British Columbia, Vancouver, British Columbia, Canada .
Cardiovascular disease is the leading cause of death for individuals with spinal cord injury (SCI). Because of a lack of a standardized and accessible animal model for cardiovascular disease after SCI, few laboratories have conducted pre-clinical trials aimed at reinstating descending cardiovascular control. Here, we utilized common contusion methodology applied to the midline of the upper-thoracic cord of adult Wistar rats accompanied with telemetric blood pressure monitoring and FluoroGold retrograde neuronal tracing, as well as lesion site and lumbrosacral afferent immunohistochemistry.
View Article and Find Full Text PDFSpinal Cord
March 2017
Clinic for Spinal Cord Injuries, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
J Neurotrauma
February 2017
8 Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, Massachusetts.
Risk factors for concussion in active-duty military service members are poorly understood. The present study examined the association between self-reported concussion history and genetics (apolipoprotein E [APOE], brain-derived neurotrophic factor [BDNF], and D2 dopamine receptor genes [DRD2]), trait personality measures (impulsive-sensation seeking and trait aggression-hostility), and current alcohol use. The sample included 458 soldiers who were preparing to deploy for Operation Iraqi Freedom/Operation Enduring Freedom.
View Article and Find Full Text PDFDisabil Rehabil Assist Technol
August 2017
b Rehabilitation Research Program , GF Strong Rehabilitation Centre, Vancouver Coastal Health Research Institute, Vancouver , BC , Canada.
Purpose: To characterize the life-space mobility and social participation of manual wheelchair users using objective measures of wheeled mobility.
Method: Individuals (n = 49) were included in this cross-sectional study if they were aged 50 or older, community-dwelling and used their wheelchair on a daily basis for the past 6 months. Life-space mobility and social participation were measured using the life-space assessment and late-life disability instrument.
Spinal Cord
January 2017
International Collaboration on Repair Discoveries, Vancouver, BC, Canada.
Study Design: Prospective cohort study.
Objectives: To determine the prevalence and course of fatigue following acute spinal cord injury (SCI) during rehabilitation and after discharge.
Setting: Tertiary spinal cord rehabilitation facility.
J Neurotrauma
January 2017
12 Health Services, Colby College, Waterville, Maine.
Relying on self-reported concussion injury history is common in both clinical care and research. However, young athletes may not provide consistent medical information. To date, little is known about the reliability of self-reported concussion history in high school students.
View Article and Find Full Text PDFJ Neurotrauma
December 2016
1 Faculty of Medicine, Division of Physical Medicine and Rehabilitation, University of British Columbia, Vancouver, British Columbia, Canada .
Sexuality is an integral part of the human experience and persists in health and disability. The cardiovascular system is crucial to sexual function and can be affected profoundly by spinal cord injury (SCI). The effects of sexual activity on the cardiovascular system in SCI have not been summarized and compared with sexual activity in able-bodied individuals.
View Article and Find Full Text PDFInt J Stroke
June 2016
St. Joseph's Healthcare - Parkwood Institute, London, ON, Canada Lawson Health Research Institute, London, ON, Canada Department of Physical Medicine and Rehabilitation, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Stroke rehabilitation is a progressive, dynamic, goal-orientated process aimed at enabling a person with impairment to reach their optimal physical, cognitive, emotional, communicative, social and/or functional activity level. After a stroke, patients often continue to require rehabilitation for persistent deficits related to spasticity, upper and lower extremity dysfunction, shoulder and central pain, mobility/gait, dysphagia, vision, and communication. Each year in Canada 62,000 people experience a stroke.
View Article and Find Full Text PDFFront Physiol
April 2016
Autonomic Research Laboratory, International Collaboration on Repair Discoveries, Faculty of Medicine, University of British ColumbiaVancouver, BC, Canada; Division of Physical Medicine and Rehabilitation, Faculty of Medicine, University of British ColumbiaVancouver, BC, Canada; GF Strong Rehabilitation Centre, Vancouver Coastal HealthVancouver, BC, Canada.
Following a spinal cord injury, there are changes in resting stroke volume (SV) and its response to exercise. The purpose of the following study was to characterize resting left ventricular structure, function, and mechanics in Paralympic athletes with tetraplegia (TETRA) and paraplegia (PARA) in an attempt to understand whether the alterations in SV are attributable to inherent dysfunction in the left ventricle. This retrospective study compared Paralympic athletes with a traumatic, chronic (>1 year post-injury), motor-complete spinal cord injury (American Spinal Injury Association Impairment Scale A-B).
View Article and Find Full Text PDFArch Phys Med Rehabil
July 2016
Graduate Program in Rehabilitation Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada; GF Strong Rehabilitation Centre, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada; Department of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
Objective: To estimate the effect of balance confidence measured at 1 month poststroke rehabilitation on perceived physical function, mobility, and stroke recovery 12 months later.
Design: Longitudinal study (secondary analysis).
Setting: Multisite, community-based.
J Neurotrauma
August 2016
1 International Collaboration on Repair Discoveries, University of British Columbia, Vancouver, British Columbia, Canada .
We sought to determine the economic burden of autonomic dysreflexia (AD) from the perspective of the Canadian healthcare system in a case series of individuals with spinal cord injury (SCI) presenting to emergency care. In doing so, we sought to illustrate the potential return on investments in the translation of evidence-informed practices and developments in the prevention, diagnosis, and management of AD. Activity-based costing methodology was employed to estimate the direct healthcare or hospitalization costs of AD following presentation to the emergency department.
View Article and Find Full Text PDFInt J Behav Med
October 2016
Department of Rehabilitation, Université Laval, Quebec City, QC, G1V 0A6, Canada.
Purpose: Approximately 85 % of Canadians are not physically active enough to achieve health benefits. Peer-led self-management programs are becoming an increasingly popular strategy for modifying health behaviors, including physical activity. The purpose of this study was to systematically review and meta-analyze the effect of peer-led self-management interventions on physical activity.
View Article and Find Full Text PDFArch Phys Med Rehabil
June 2016
Department of Neurological Surgery, University of Louisville, Louisville, Kentucky. Electronic address:
Spinal Cord
June 2016
Rehabilitation Research Program, Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada.
Study Design: Cross-sectional national survey.
Objectives: To explore the association between fatigue and community participation frequency and provide an adjusted model of the relationship including important covariates.
Setting: Canada; Community.
Arch Phys Med Rehabil
March 2016
Rehabilitation Research Program, GF Strong Rehabilitation Centre, Vancouver, British Columbia, Canada.
Objectives: To identify and critically appraise potential participation measurement tools for children aged 18 months to 17 years with power mobility (PM) needs.
Data Sources: Searches in 9 electronic databases identified peer-reviewed publications in English to January 2015, along with hand-searching included bibliographies.
Study Selection: The Preferred Reporting Items for Systematic reviews and Meta-Analyses statement was followed with inclusion criteria set a priori.
Arch Phys Med Rehabil
January 2016
Graduate Program in Rehabilitation Sciences, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada; Rehabilitation Research Program, Vancouver Coastal Research Institute, GF Strong Rehabilitation Centre, Vancouver, British Columbia, Canada; Department of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Objectives: To evaluate the effect of a peer-led wheelchair training program on self-efficacy of manual wheelchair (MWC) use and to explore influences of the intervention on MWC skills, life-space mobility, and satisfaction with participation.
Design: Pilot randomized controlled trial.
Setting: Rehabilitation center and community.
Am J Phys Med Rehabil
November 2015
From the International Collaboration on Repair Discoveries (CRW, KDC, CG, AVK, JB), School of Kinesiology (CRW), Department of Medicine, Division of Physical Medicine and Rehabilitation (AVK), University of British Columbia, Vancouver, British Columbia, Canada; GF Strong Rehabilitation Centre, Vancouver Health Authority, Vancouver, British Columbia, Canada (AVK); and British Columbia Institute of Technology, Burnaby, British Columbia, Canada (JB).
In a 43-yr-old male subject with a chronic T3 AIS A spinal cord injury, the acute cardiorespiratory responses to active upper-extremity exercise alone and combined active-arm passive-leg exercise (AAPLE) were investigated, along with the cardiorespiratory, cardiac, vascular, and body composition responses to a 6-wk AAPLE interval training intervention. AAPLE elicited superior acute maximal cardiorespiratory responses compared with upper-extremity exercise alone. In response to a 6-wk interval training regimen, AAPLE caused a 25% increase in peak oxygen uptake, a 10% increase in resting stroke volume, and a 4-fold increase in brachial artery blood flow.
View Article and Find Full Text PDFPhys Ther
March 2016
J.J. Eng, PT, PhD, Department of Physical Therapy, University of British Columbia, 212-2177 Wesbrook Mall, Vancouver, British Columbia, Canada V6T 1Z3.
Background: As physical activity in people poststroke is low, devices that monitor and provide feedback of walking activity provide motivation to engage in exercise and may assist rehabilitation professionals in auditing walking activity. However, most feedback devices are not accurate at slow walking speeds.
Objective: This study assessed the accuracy of one accelerometer to measure walking steps of community-dwelling individuals poststroke.
Clin Rehabil
June 2016
Department of Medicine, University of British Columbia, Vancouver, BC, Canada GF Strong Rehabilitation Centre, Vancouver, BC, Canada.
Objective: To determine the quality of evidence from randomized controlled trials on the efficacy of adjunct therapies following botulinum toxin injections for limb spasticity.
Data Sources: MEDLINE, EMBASE, CINAHL, and Cochrane Central Register of Controlled Trials electronic databases were searched for English language human studies from 1980 to 21 May 2015.
Study Selection: Randomized controlled trials assessing adjunct therapies postbotulinum toxin injection for treatment of spasticity were included.
Neurorehabil Neural Repair
May 2016
University of British Columbia, Vancouver, British Columbia, Canada GF Strong Rehabilitation Centre, Vancouver Health Authority, British Columbia, Canada
Background: Spinal cord injury (SCI) induces alterations in cardio-autonomic control of which autonomic dysreflexia (AD), a condition characterized by life-threatening hypertension, is arguably the most insidious. Passive hind-limb cycling represents a low-cost therapeutic intervention with demonstrable cardiovascular, sensory, and motor benefits.
Objective: To investigate the effect of passive hind-limb cycling on AD in rodents with T3 SCI.
J Neurotrauma
February 2016
3 International Collaboration on Repair Discoveries, University of British Columbia, Vancouver, British Columbia, Canada .
Autonomic dysreflexia (AD) is a life-threatening episode of transient hypertension affecting up to 90% of those with high-level spinal cord injury (SCI), and can lead to cerebral hemorrhage. Due to the nature of this medical emergency, cerebral blood flow (CBF) has not been recorded during AD. Beat-by-beat blood pressure (BP) and CBF velocity of the middle cerebral artery were measured during spontaneous AD episodes in four motor complete cervical SCI patients.
View Article and Find Full Text PDFSpinal Cord
November 2015
Department of Spinal Cord Injuries, Rigshopitalet, Copenhagen, Denmark.
Phys Ther
October 2015
C.L. Backman, PhD, FCAOT, Graduate Program in Rehabilitation Sciences and Department of Occupational Science and Occupational Therapy, University of British Columbia.
Background: There are no predictive models of wheelchair-use confidence. Therefore, clinicians and researchers are limited in their ability to screen for and identify wheelchair users who may be more prone to low wheelchair-use confidence and may benefit from clinical intervention.
Objective: The purpose of this study was to identify health-related, personal, and environmental factors that predict perceived wheelchair-use confidence in community-dwelling adults who use manual wheelchairs.
Dev Neurorehabil
December 2016
c Sunny Hill Health Centre for Children, Therapy , Vancouver , British Columbia , Canada.
Objectives: To identify suitable tools for measuring important elements of participation for children, aged 18 months to 12 years, who need or use power mobility, and to indicate which tools should be considered for inclusion in a measurement toolkit.
Methods: Parents, therapists and researchers with expertise in paediatric power mobility and participation (n = 70) completed an online modified Delphi survey, with consensus set a priori >80% agreement. Existing tools were matched against participation elements ranked most important for those in early childhood (18 months-5 years) and of school-age (6-12 years) by the panel.
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